Structure and function of RNA-protein complexes
Our newest paper describing the structure of the catalytic core of the Integrator complex is online now in Molecular Cell. Integrator complex was discovered more than 15 years ago as a specialised endonuclease responsible for the 3’-end processing of spliceosomal snRNAs. More recent studies…
A warmly welcome to our 2 newest lab members, Angelique and Sunny! Angelique joined as a research technician, after spending 5 years in Irina Gutsche’s group at IBS in Grenoble. Sunny joined as a new postdoc in November, after completing her PhD in Patrick Cramer’s group at MPI-BPC in…
Congratulations to Michal Razew, EIPOD4 postdoctoral fellow in the lab, for receiving the Prime Minister of Poland award for his PhD dissertation at the International Institute of Molecular and Cell Biology in Warsaw.
Check out our latest pre-print from the Nagai group identifying a new spliceosome assembly intermediate. The most complete and accurate depiction of the catalytic spliceosome to date; 9 datasets, 12 focused maps, 4 years in making. Fantastic effort by Max Wilkinson and Sebastian Fica.…