Edit

Tag:

typas

Showing results out of

Year

29 May 2026 side-by-side head shots of three female scientists

side-by-side head shots of three female scientists

Fellowships expand research horizons

EMBL-UNESCO fellows reflect on experiences at EMBL that broadened their own research capacity while providing new perspectives to collaborators.

PEOPLE & PERSPECTIVES

2026

people-perspectives

24 September 2024 Illustration showing several drugs being broken down when reaching a community of gut bacteria. This community has different types of bacteria.

Illustration showing several drugs being broken down when reaching a community of gut bacteria. This community has different types of bacteria.

Better together: gut microbiome communities’ resilience to drugs

EMBL Heidelberg researchers compared the effect of drugs on isolated bacteria versus those growing in communities. This is the first study showing that bacteria are more resilient when in community due to cross-protection strategies. This could help researchers design more efficient therapies.

SCIENCE & TECHNOLOGY

2024

science-technology

11 September 2024 Photographs of two scientists against a green-blue background.

Photographs of two scientists against a green-blue background.

New directions for molecular systems biology at EMBL

Julia Mahamid and Nassos Typas reflect on the direction of the Molecular Systems Biology Unit they now lead at EMBL Heidelberg.

PEOPLE & PERSPECTIVES

2024

people-perspectives

17 October 2023 Pill icons representing different antibiotic classes are seen exerting their effects on a bacterium, whose cell wall, membrane, and protein synthesis machinery (two different classes) can be seen as potential targets. Curved lines connect the pills to each other, representing synergies in drug interactions. More bacteria can be seen in the background.

Pill icons representing different antibiotic classes are seen exerting their effects on a bacterium, whose cell wall, membrane, and protein synthesis machinery (two different classes) can be seen as potential targets. Curved lines connect the pills to each other, representing synergies in drug interactions. More bacteria can be seen in the background.

Fighting antimicrobial resistance with new drug combinations

In an extensive investigation, EMBL researchers have tested over 10,000 drug combinations against some of the leading pathogenic bacteria carrying antimicrobial resistance and causing mortality.

SCIENCE & TECHNOLOGY

2023

sciencescience-technology

21 December 2022 Test tubes with different colours; the deeper the red colour of the growth medium, the stronger is the disruptive effect of the drug on the bacterial envelope

Test tubes with different colours; the deeper the red colour of the growth medium, the stronger is the disruptive effect of the drug on the bacterial envelope

Spotlight: Establishing a colour palette for antibiotic resistance

To identify which drugs disrupt bacterial envelope integrity, the Typas group uses a molecule called chlorophenyl red-β-D-galactopyranoside.

LAB MATTERS SCIENCE & TECHNOLOGY

2022

lab-matterspicture-of-the-weekscience-technology

18 July 2022 Large, elongated purple molecule has an on/off switch on it pointed to on.

Large, elongated purple molecule has an on/off switch on it pointed to on.

The retron switch

EMBL researchers now understand the function of an elusive small DNA in bacteria and have developed a tool that can be used to better understand what might ‘switch on’ bacterial immune defences.

SCIENCE & TECHNOLOGY

2022

sciencescience-technology

6 July 2022 Potrait image of the three elected members with a blue wavy background

Potrait image of the three elected members with a blue wavy background

Three EMBL scientists elected as EMBO Members

Cornelius Gross, Miki Ebisuya and Nassos Typas join EMBO, the prestigious organisation for the life sciences.

EMBL ANNOUNCEMENTS LAB MATTERS

2022

embl-announcementslab-matters

13 October 2021 Illustration of a community of bacteria. Pills represent an antibiotic that can be used to treat an infection, and a second drug that could protect many gut bacteria from antibiotics.

Illustration of a community of bacteria. Pills represent an antibiotic that can be used to treat an infection, and a second drug that could protect many gut bacteria from antibiotics.

Tackling the collateral damage from antibiotics

Researchers from EMBL’s Typas group and collaborators have analysed the effects of 144 antibiotics on the wellbeing of gut microbes. The study improves our understanding of antibiotics’ side effects and suggests a new approach to mitigating the adverse effects of antibiotics therapy on gut…

SCIENCE & TECHNOLOGY

2021

sciencescience-technology

8 September 2021 Illustration of two halves of a pill, which releases chemical molecules that are taken up by gut bacteria in the vicinity.

Illustration of two halves of a pill, which releases chemical molecules that are taken up by gut bacteria in the vicinity.

Common medications accumulate in gut bacteria

A new collaborative study led by EMBL group leaders Kiran Patil, Nassos Typas, and Peer Bork has found that common medications accumulate in human gut bacteria. This process reduces drug effectiveness and affects the metabolism of common gut microbes, thereby altering the gut microbiome.

SCIENCE & TECHNOLOGY

2021

sciencescience-technology

7 July 2021 Fluorescence microscopy image of a cell and symbolic representation of a protein network.

Fluorescence microscopy image of a cell and symbolic representation of a protein network.

New insights into Salmonella’s survival strategies

Research in the Typas group uncovers new details of the strategies Salmonella uses to survive in infected cells.

SCIENCE & TECHNOLOGY

2021

sciencescience-technology

15 March 2021

VAAM Research Award for Nassos Typas

Nassos Typas has received the German VAAM Research Award.

EMBL ANNOUNCEMENTS LAB MATTERS

2021

embl-announcementslab-matters

16 February 2021 Microscopy images of coronavirus-infected cells in blue and red, arranged on a clockface. Illustrations of virus particles.

Microscopy images of coronavirus-infected cells in blue and red, arranged on a clockface. Illustrations of virus particles.

Finding coronavirus’s helper proteins

A team of EMBL scientists and colleagues have analysed how the novel coronavirus affects proteins in human cells. They identified several human proteins as potential drug targets to prevent viral replication.

SCIENCE & TECHNOLOGY

2021

sciencescience-technology

9 December 2020 Illustration of a rod-shaped bacterial cell, superimposed on a red and blue background.

Illustration of a rod-shaped bacterial cell, superimposed on a red and blue background.

Heating proteins to understand how genes work

A new paper from EMBL’s Savitski team and Typas group describes their work on E. coli and how it brings a greater understanding of the way genes function and interact.

SCIENCE & TECHNOLOGY

2020

sciencescience-technology

16 July 2020 A collage of portrait photos of Jessica Vamathevan, Jan Korbel, and Nassos Typas.

A collage of portrait photos of Jessica Vamathevan, Jan Korbel, and Nassos Typas.

Changes in senior roles at EMBL

Three changes in senior staff positions have been confirmed at EMBL today. Jessica Vamathevan becomes Head of Strategy, Jan Korbel becomes Head of Data Science for EMBL Heidelberg, and Nassos Typas becomes Senior Scientist.

EMBL ANNOUNCEMENTS LAB MATTERS

2020

embl-announcementslab-matters

8 June 2020 Microscopic image showing a macrophage that has been infected with Salmonella (green), causing cellular cathepsins (red) to locate to the nucels (blue).

Microscopic image showing a macrophage that has been infected with Salmonella (green), causing cellular cathepsins (red) to locate to the nucels (blue).

Re-trafficking proteins to fight Salmonella infections

Scientists including members of EMBL’s Typas group have investigated how immune cells called macrophages respond to infection by the intracellular pathogen Salmonella enterica. They discovered that Salmonella causes newly produced cathepsins to accumulate in the nuclei of infected cells to…

SCIENCE & TECHNOLOGY

2020

sciencescience-technology

16 April 2020 Micropipette tips in a liquid-handling robot

Micropipette tips in a liquid-handling robot

Helping to scale up coronavirus testing

Scientists at EMBL Heidelberg are contributing their expertise in a community effort to develop large-scale testing methods for coronavirus. Their goal is to increase the capacity and speed of testing, which is crucial for containing the pandemic.

SCIENCE & TECHNOLOGY

2020

sciencescience-technology

15 April 2020

Identifying how potential COVID-19 drugs work

EMBL researchers are studying how drugs that have shown good results against COVID-19 work in living cells

SCIENCE & TECHNOLOGY

2020

sciencescience-technology

2 April 2020 Map showing institutes involved with EMBL in Twinning projects

Map showing institutes involved with EMBL in Twinning projects

EMBL shares expertise with four European institutes

Three international teams involving EMBL Heidelberg have been granted funding from the European Commission for three Twinning projects with institutes in Portugal and the Czech Republic.

CONNECTIONS LAB MATTERS

2020

connectionslab-matters

22 November 2018 Portrait of Nina Kathe

Portrait of Nina Kathe

Ambition and talent

Nina Kathe, Winner of the EU Contest for Young Scientists visits EMBL

LAB MATTERS

2018

eventslab-matters

6 July 2018 E. coli bacteria colored in heat gradient. IMAGE: Aleksandra Krolik / EMBL

E. coli bacteria colored in heat gradient. IMAGE: Aleksandra Krolik / EMBL

Melting bacteria to decipher antibiotic resistance

EMBL scientists investigate how bacteria melt to study their reaction to drugs

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

4 July 2018

Combining antibiotics changes their effectiveness. IMAGE: Aleksandra Krolik / EMBL

Combining antibiotics changes their effectiveness

Combining antibiotics with each other, non-antibiotic drugs or food additives can alter their effectiveness

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

19 March 2018

Commonly used drugs affect our gut bacteria.

Commonly used drugs affect our gut bacteria

One in four drugs with human targets inhibit the growth of bacteria in the human gut, and may promote antibiotic resistance, EMBL researchers report in Nature

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

19 March 2018

Molecular cuisine for gut bacteria. IMAGE: Aleksandra Krolik / EMBL

Molecular cuisine for gut bacteria

EMBL scientists show how to grow a wide range of gut bacteria in the lab

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

18 December 2014

Bacteria’s barrel-building challenge

How do E.coli and similar bacteria grow safely? By using barrel-plugs as sensors.

SCIENCE & TECHNOLOGY

2014

sciencescience-technology

No results found

Edit