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The Influenza virus

Understanding the influenza virus

The infectious disease commonly known as flu is caused by the influenza virus. It spreads around the world in seasonal outbreaks, causing millions of infections and hundreds of thousands of deaths each year. Stephen Cusack, Head of EMBL Grenoble, has been studying different aspects of the influenza virus for 30 years. Here, he describes how the influenza virus functions, the technologies that are helping researchers to understand it, and why it’s necessary to constantly develop new drugs.

By Fabian Oswald

Science

Influenza polymerase (light cyan) in the process of synthesising messenger RNA (slate blue).

Paving the way for new flu drugs

Snapshots of the flu virus replication machine in action

By Mathias Jäger

Science

Mutations at the amino acid shown in orange (isoleucine 38) lead to reduced susceptibility to the drug. IMAGE - Stephen Cusack, EMBL

Flu’s response to new drug explored

EMBL scientists investigate how influenza virus responds to new drug treatment

By Iris Kruijen

Science

Bigger, better, faster

The molecular machine that makes essential components of ribosomes – the cell’s protein factories – is like a Swiss-army knife, researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and the Centro de Investigaciones Biológicas in Madrid, Spain, have found. By determining the 3-dimensional structure of this machine, called RNA polymerase I, for […]

By Guest author(s)

Science

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