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integrative modelling

21 December 2021 A model of the doughnut-shaped nuclear pore complex. Individual molecules are marked in various colours.

A model of the doughnut-shaped nuclear pore complex. Individual molecules are marked in various colours.

Observing the secret life of molecules inside the cell

25 June 2021 A close up into the inner membrane of a mycobacterium shows a 3D model of the molecular structure of the mycobacterial secretion system ESX-5, which is located in the inner membrane and consists of multiple proteins shown in different colours.

A close up into the inner membrane of a mycobacterium shows a 3D model of the molecular structure of the mycobacterial secretion system ESX-5, which is located in the inner membrane and consists of multiple proteins shown in different colours.

Structural biology reveals new opportunities to combat tuberculosis

3 September 2020 Left: Slice of a cell in grey. Right: Two 3D reconstructions of parts of the slice, showing the internal structure.

Left: Slice of a cell in grey. Right: Two 3D reconstructions of parts of the slice, showing the internal structure.

Nuclear pores in their natural context

11 July 2019 Structure of the Elongator complex

Structure of the Elongator complex

A tRNA modifier at work

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