The speed of life: a zoo of cells to study developmental time
Science Researchers from the Ebisuya Group at EMBL Barcelona have used an unprecedented stem cell zoo to compare six different mammalian species and their developmental time.
2023
science
Zooming in to get the full picture
Science EMBL and UW researchers plus additional collaborators have constructed a complete map of fruit fly embryonic development using machine learning. This research is foundational to better understanding overall embryo development in other species, including humans.
2022
science
Unravelling the origins of the human spine
Science Scientists at EMBL Barcelona have created for the first time a 3D in vitro model that recapitulates the periodic formation of human somites – structures that give rise to the spinal column.
2022
science
A metaphor for epigenetic inheritance
Science Recent studies from the Hackett group at EMBL Rome have revealed new insights on the mechanism regulating transmission of non-genetic information during embryonic development, and inspired a scientific illustration
2022
science
A 3D culture model to study embryo growth
Science A recent study by EMBL researchers proposes a new method to grow early embryos in the laboratory. With a 3D culture set-up, scientists can closely monitor the changes embryos undergo around the time of implantation.
2022
science
Converging lenses on embryo development
Science Researchers from the Furlong group at EMBL have come up with a way to observe the development of fruit-fly embryos simultaneously at the genetic and cellular levels, generating a high-resolution and integrated view of how different cell lineages form.
2022
science
Welcome: Michael Dorrity
Lab Matters Michael Dorrity, one of EMBL’s newest group leaders, is studying how the environment influences early life stages in zebrafish.
2022
lab-matters
The Spatial Mouse Atlas: new insights into cell fate
Science Researchers have combined spatial gene expression information with single-cell genomics data to create a high-resolution atlas of mouse organogenesis.
2021
science
Welcome: Ana Boskovic
Lab Matters The new group leader at EMBL Rome will study how embryos can inherit non-genetic information from their parents that causes stable and heritable effects
2021
lab-matters
Welcome: Nicoletta Petridou
Lab Matters New group leader Nicoletta Petridou explains her fascination with the complexity of early embryo development, and how the interdisciplinary nature of EMBL will aid her research.
2021
lab-matters
EMBL group leader Miki Ebisuya receives ERC Consolidator Grant
Lab Matters Funding by the European Research Council (ERC) will support research on the timing of developmental processes in mammals
2020
lab-matters
Human and mouse cells run at different speeds
Science The internal clock that governs the development of embryos ticks slower for humans than for mice. Differences in the speed of biochemical reactions underlie the differences between species in the tempo of development.
2020
science
Unprecedented single-cell studies in virtual embryo
Science Researchers from EMBL Heidelberg have created a complete description of early embryo development, accounting for every single cell in the embryo.
2020
science
How chromosome structure influences development
Science EMBL researchers in the Heard group at EMBL Heidelberg explore the interaction between DNA organisation and gene expression in the early embryo
2020
science
Tissue dynamics provide clues to human disease
Science EMBL scientists examine the molecular causes of a rare hereditary disease of the spine and ribs
2020
science
Accidental beauty
Picture of the week In the Trivedi Group at EMBL Barcelona, Krisztina Arató and Jia Le Lim study the early development of zebrafish embryos.
2020
picture-of-the-week
Controlling organ growth with light
Science The De Renzis group investigated invagination, the first step of organ development in embryos.
2018
science
The scientific origins of Edith Heard
Science EMBL’s next Director General reflects on the questions that drive her research
2018
science
From blood vessels to blood stem cells
Science EMBL scientists discover how blood vessel cells become blood stem cells during embryonic development
2018
science
Synchronised waves control embryonic patterning
Science EMBL scientists show that the rhythm between Wnt and Notch waves enables patterning in embryos.
2018
science
DNA’s twisted communication
Science During embryo development, genes are dynamically, and very precisely, switched on and off to confer different properties to different cells and build a well-proportioned and healthy animal. Fgf8 is one of the key genes in this process, controlling in particular the growth of the limbs and…
2013
science
Collective action
Science If you wanted to draw your family tree, you could start by searching for people who share your surname. Cells, of course, don’t have surnames, but scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found that genetic switches called enhancers, and the…
2012
science
Uncovering how cells cover gaps
Science Researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, came a step closer to understanding how cells close gaps not only during embryonic development but also during wound healing. Their study, published this week in the journal Cell, uncovers a fundamental…
2009
science
Digital zebrafish embryo provides the first complete developmental blueprint of a vertebrate
Science Researchers at the European Molecular Biology Laboratory (EMBL) have generated a digital zebrafish embryo – the first complete developmental blueprint of a vertebrate. With a newly developed microscope scientists could for the first time track all cells for the first 24 hours in the life of a…
2008
science
A molecule that protects from neuronal disorders
Science Many neuronal disorders, including epilepsy, schizophrenia and lissencephaly ─ a form of mental retardation ─ result from abnormal migration of nerve cells during the development of the brain. Researchers from the Mouse Biology Unit of the European Molecular Biology Laboratory (EMBL) in Italy,…
2007
science
A wandering eye
Science Eyes are among the earliest recognisable structures in an embryo; they start off as bulges on the sides of tube-shaped tissue that will eventually become the brain. Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg have now discovered that cells are programmed to make…
2006
science
A switch between life and death
Science Cells in an embryo divide at an amazing rate to build a whole body, but this growth needs to be controlled. Otherwise the result may be defects in embryonic development or cancer in adults. Controlling growth requires that some cells divide while others die; their fates are determined by signals…
2006
science
How do cells travel through our bodies?
Science One of the most basic yet least understood processes in our bodies is how cells crawl along tissues. This behavior is essential to the formation of an embryo and other processes, but it must be tightly controlled. A disturbance can lead to the spread of cancer cells or diseases like Spina…
2005
science
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