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embryo Archives | EMBL

Cell division

Tracing the origins of cells

Researchers from the Sharpe group at EMBL Barcelona have published a method to track the developmental history of a cell using the gene editing tool CRISPR–Cas9, but without the need to create transgenic organisms.

By Fabian Oswald

Science

A 4D visualisation of single-cell expression patterns. Credit: Hanna Sladitschek/EMBL

Unprecedented single-cell studies in virtual embryo

Researchers from EMBL Heidelberg have created a complete description of early embryo development, accounting for every single cell in the embryo.

By Mathias Jäger

Science

The zebrafish earned its stripes

Despite missing the characteristic stripes one would expect from a zebra – or a zebrafish – the fractals in this Picture of the Week show a zebrafish; or at least some cells in a zebrafish embryo, a few hours after fertilisation. Zebrafish are not only popular aquarium fish, they are also an important and widely […]

By Mathias Jäger

Picture of the week

An in silico hope for biology: machine learning

How EMBL scientists are using machine learning to advance biology

By Berta Carreño

Lab Matters

Top view picture of modified and natural invagination in a tissue

Controlling organ growth with light

The De Renzis group investigated invagination, the first step of organ development in embryos.

By Patrick Mueller

Science

Optical section of a ‘gastruloid’ – an embryonic organoid made from mouse embryonic stem cells and stained for E-Cadherin (red), marking cell outlines and nuclei (blue). IMAGE: Vikas Trivedi/EMBL

Welcome: Vikas Trivedi

An engineer’s approach to understanding morphogenesis

By Berta Carreño

Science

Artistic 3D rendering of the dual spindle in the mammalian zygote. IMAGE: Cartasiova, Hossain, Reichmann, Ellenberg/EMBL

Parental chromosomes kept apart during first division

Mammalian life begins differently than we thought

By Iris Kruijen

Science

Without a trace

Migrating cells, it seems, cover their tracks not for fear of being followed, but to keep moving forward. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have now shown that cells in a zebrafish embryo determine which direction they move in by effectively erasing the path behind them. The findings, published online […]

By Guest author(s)

Science

Cells eat themselves into shape

The process cells use to ‘swallow’ up nutrients, hormones and other signals from their environment – called endocytosis – can play a crucial role in shaping the cells themselves, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found. The study, published today in Nature Communications, could help explain how the cells on […]

By Guest author(s)

Science

Sync to grow

In a nutshell: The size of pre-vertebrae in a mammalian embryo is controlled by a wave-like gene expression pattern along its back The size of each pre-vertebra is proportional to the speed of the wave: the faster the wave, the bigger the vertebra Embryonic cells coordinate gene activities with each other to adapt the size […]

By Guest author(s)

Science

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