Tag:

chromosome structure

Year

22 March 2023 Artistic representation that features a long, winding helix joining together a doughnut-figure to a small shaggy ball to indicate the connections long-read sequencing can make about DNA mutations.

Artistic representation that features a long, winding helix joining together a doughnut-figure to a small shaggy ball to indicate the connections long-read sequencing can make about DNA mutations.

The ‘long read’ for cancer

Science Using Oxford Nanopore long-read sequencing, EMBL scientists sequenced a primary childhood brain tumour known as a medulloblastoma, uncovering a novel complex mutation pattern.

2023

science

3 June 2022 he internal structure of a mitotic chromosome is shown with colourful threads representing DNA, one of which is shown being packaged into loops by the condensin protein complex. The background shows mitotic chromosomes in the cellular space

he internal structure of a mitotic chromosome is shown with colourful threads representing DNA, one of which is shown being packaged into loops by the condensin protein complex. The background shows mitotic chromosomes in the cellular space

Shaping up the genome for cell division

Science Researchers have discovered the mechanism by which a family of DNA motor proteins packages loosely arranged strands of DNA into compact individual chromosomes during cell division.

2022

science

9 April 2020 3D reconstruction of parental chromosomes in the mouse embryo

How chromosome structure influences development

Science EMBL researchers in the Heard group at EMBL Heidelberg explore the interaction between DNA organisation and gene expression in the early embryo

2020

science

20 June 2019 Structural biology image of the condensin complex.

Intact chromosomes during cell division

Science The mystery of how condensin maintains the integrity of the genome during cell division.

2019

science

23 May 2018 As a cell prepares to divide, the chromosomes (shown here in pink) condense, becoming more tightly coiled and easier to observe under the microscope. The faint structure in the centre is a cell nucleus in which the chromosomes are in their usual decondensed state.

As a cell prepares to divide, the chromosomes (shown here in pink) condense, becoming more tightly coiled and easier to observe under the microscope. The faint structure in the centre is a cell nucleus in which the chromosomes are in their usual decondensed state.

Exploring genetic variation

Science EMBL group leader Jan Korbel reflects on his scientific origins and current research

2018

science

22 February 2018 A condensin protein complex creates a loop in DNA. IMAGE: Cees Dekker Lab TU Delft/Scixel

Loops, loops and loops: how DNA gets organised

Science Researchers from Delft University and EMBL crack the mystery of condensin’s neat DNA loop extrusion

2018

science

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Tag:

chromosome structure

The ‘long read’ for cancer

Shaping up the genome for cell division

How chromosome structure influences development

Intact chromosomes during cell division

Exploring genetic variation

Loops, loops and loops: how DNA gets organised

EMBLetc.

Read the latest Issues of our magazine - EMBLetc.

Issue 100, Summer 2023

Issue 99, Winter 2022

Tag:

chromosome structure

EMBLetc.

Read the latest Issues of our magazine - EMBLetc.

Issue 100, Summer 2023

Issue 99, Winter 2022

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