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Biochemistry

Artistic representation of the structure of the three proteins forming Integrator’s catalytic core.

At the core of the Integrator complex

A new paper from the Galej group at EMBL Grenoble describes the structure of key parts of the Integrator complex, involved in gene…

By Mylène André

Science
Portrait photo of EMBL group leader Miki Ebisuya against a green background.

EMBL group leader Miki Ebisuya receives ERC Consolidator Grant

Funding by the European Research Council (ERC) will support research on the timing of developmental processes in…

By Marius Bruer

Lab Matters
Graphical representation of genome editing tool CRISPR in green and pink. Nobel prize medal on the right.

Powerful genome editing tool recognised by Nobel Prize in Chemistry

The genome editing tool CRISPR–Cas9 – which plays a critical role in EMBL’s research – was recognised by the Nobel Prize in…

By Ivy Kupec

Science
A metal rack holding glass test tubes with yellow and red solutions in them.

Colourful test tubes

To study the effect of commonly used drugs on bacterial envelopes, EMBL scientists applied a biochemical assay using a colour reaction. The deeper…

By Marius Bruer

Picture of the week
Composite image of mouse cells and human cells showing different levels of luminescence, indicated as different colours.

Human and mouse cells run at different speeds

The internal clock that governs the development of embryos ticks slower for humans than for mice. Differences in the speed of biochemical reactions…

By Luca Tancredi Barone

Science
Super-resolution image of the basal surface of a cellularising Drosophila embryo.

Actin crosslinking plays key role in tissue morphogenesis

New insights into mechanisms behind embryonic…

By Cella Carr

Science
HiGlass (http://higlass.io) is an exploratory visualization tool for genomic data developed by Nils Gehlenborg and his team that provides analysts with a flexible interface to explore genomic and epigenomic data, including genome wide interactions, across multiple scales. IMAGE: Nils Gehlenborg

Kendrew and Philipson Awards Winners 2018

EMBL recognises the outstanding work of alumni with the John Kendrew and Lennart Philipson…

By Berta Carreño

Alumni
Alasdair McDowall (left), an EMBL research technician 1978-1987, and Jacques Dubochet (right), EMBL group leader 1978-1987, together in Heidelberg

Alasdair McDowall’s slow road to flash freezing

How a research technician with a master’s degree contributed to Nobel Prize-winning…

By Sarah B. Puschmann

Alumni
Jacques Dubochet visiting EMBL in 2015 to receive the inaugural Lennart Philipson Award

Jacques Dubochet awarded Nobel Prize for chemistry

EMBL alumnus recognised for cryo-electron microscopy…

By Adam Gristwood

Science
Paris at night. IMAGE: NASA (M. Justin Wilkinson, Texas State University, Jacobs Contract at NASA-JSC)

Life in the periphery

Storage of pre-made nuclear pores allows for rapid cell division in fruit fly…

By Margaux Phares

Science
Landline vs. smartphone: the RNA-binding domain lets proteins do more than just talk to other proteins

Discovering protein smartphones

New technique reveals uncharted docking sites in RNA-binding…

By Margaux Phares

Science
The ultrafast and yet selective binding allows the receptor (gold) to rapidly travel through the pore filled with disordered proteins (blue) into the nucleus, while any unwanted molecules are kept outside. IMAGE: Mercadante /HITS

Floppy but fast

Spaghetti-like proteins are surprisingly effective…

By Guest author(s)

Science

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