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bhogaraju

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6 March 2024 The background shows a render of a suspension of tumour cells, while an inset shows the structures of two proteins – MAGEA4 and RAD18 – marked in green and blue respectively

Studying the relationship between cancer-promoting proteins

Science & Technology A new study from the Bhogaraju Group at EMBL Grenoble reveals how the cancer-promoting MAGE family of proteins bind to their targets, aiding the development of anti-cancer drugs that target these proteins.

2024

sciencescience-technology

20 December 2021 A detailed structure map shows two proteins interacting in the foreground, each shown in a different colour. The background shows small green dots marking bacteria

Solving molecular puzzles to find the perfect fit

Science & Technology Using cryo-EM and structural biology techniques, EMBL researchers have shown how two proteins of Legionella pneumophila interact. This finding sheds light on a mechanism critical to the infection process and could lead to the development of new drugs to treat pneumonia.

2021

sciencescience-technology

17 June 2020 Crystal selection for X-ray diffraction experiments.

Investigating the structure and mechanisms of coronavirus biomolecules

Science & Technology While global research on coronaviruses has shed light on the function of many SARS-CoV-2 proteins, the role of some crucial components remains unknown. Researchers at EMBL Grenoble will use a range of structural biology methods to try to solve some of the puzzles of the molecular mechanics of…

2020

sciencescience-technology

8 March 2019 Sagar Bhogaraju portrait photo

Welcome: Sagar Bhogaraju

Science & Technology New group leader at EMBL Grenoble is investigating the cellular role of melanoma antigens

2019

sciencescience-technology

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