Prevedel Group Archives

20 February 2025

Pushing the limits of ‘custom-made’ microscopy

Another EMBL-engineered advance to Brillouin microscopy has significantly widened the aperture to provide quick 3D imaging in real time of light-sensitive samples.

SCIENCE & TECHNOLOGY

2025

science-technology

17 December 2024 The image has a big circle with a microscopy image of an organism inside. Then, at the right, another circle (smaller) with a scientist looking into a screen. In the backgroup there is a truck.

The image has a big circle with a microscopy image of an organism inside. Then, at the right, another circle (smaller) with a scientist looking into a screen. In the backgroup there is a truck.

A new EMBL microscope hits the road

The Prevedel group at EMBL Heidelberg developed a mobile microscope: miniature in scale, fast in sample imaging, and giant in resolution.

SCIENCE & TECHNOLOGY

2024

science-technology

10 September 2024 A brain section is seen in the background, from which a 'highway'emerges, with lit up neurons spaced like cars on the highway.

Follow the cellular road

An AI-enhanced advanced microscopy approach offers promise in better understanding glioblastomas, one of the deadliest brain cancers.

SCIENCE & TECHNOLOGY

2024

science-technology

27 August 2024 In the foreground is a photoacoustic dye from the red end of the visible spectrum that is ‘turned on’. It produces an ultrasound emission that can be detected and measured. A dye that is ‘turned off’ is shown in the left background.

In the foreground is a photoacoustic dye from the red end of the visible spectrum that is ‘turned on’. It produces an ultrasound emission that can be detected and measured. A dye that is ‘turned off’ is shown in the left background.

Seeing into the depths

EMBL scientists applied molecular engineering to build photoacoustic probes to label and visualise neurons deep within brain tissue.

SCIENCE & TECHNOLOGY

2024

science-technology

25 January 2024 An oval light blue shape. In the central part, there is a smaller a red object, from which stem many highly branched smaller canals that cover a significant part of the blue surface. The whole sponge image is in placed in a circle. The background around the circle is blue-green.

An oval light blue shape. In the central part, there is a smaller a red object, from which stem many highly branched smaller canals that cover a significant part of the blue surface. The whole sponge image is in placed in a circle. The background around the circle is blue-green.

Ancient ‘relaxant-inflammatory’ response gets sponges moving

Sponges lack muscles and neurons. Yet, they make coordinated movements. Scientists at EMBL Heidelberg have discovered that sponge movement is controlled by an ancient ‘relaxant-inflammatory’ response that is also present in vertebrate blood vessels. The findings shed light on sponge physiology…

SCIENCE & TECHNOLOGY

2024

sciencescience-technology

30 March 2023 Science illustration representing two embryos imaged using the Brillouin microscopy technique. The embryo in the front is a mouse embryo at 20h and the one in the back a Phallusia mammillata embryo. A laser beam crosses the samples to analyse tissue stiffness (here represented by acoustic waves).

Science illustration representing two embryos imaged using the Brillouin microscopy technique. The embryo in the front is a mouse embryo at 20h and the one in the back a Phallusia mammillata embryo. A laser beam crosses the samples to analyse tissue stiffness (here represented by acoustic waves).

Shining light on the mechanics of embryo development

A new microscope built by EMBL researchers, based on Brillouin scattering principles, allows scientists to observe the dynamics of mechanical properties inside developing embryos in real time.

LAB MATTERS SCIENCE & TECHNOLOGY

2023

lab-matterssciencescience-technology

23 February 2023 Image showing the pulsed green laser exciting the photoacoustic signal of the sample in the cuvette.

Spotlight: Using light and sound to see into the brain

Researchers in the Prevedel Group use photoacoustic spectroscopy setup to test and optimise probes before their usage in mouse neuroscience.

LAB MATTERS SCIENCE & TECHNOLOGY

2023

lab-matterspicture-of-the-weekscience-technology

16 September 2022 Four blue forms against a black background that transition from small circle to oval to tubular shapes.

Does exercise drive development? In the sea anemone, the way you move matters.

The latest research from EMBL’s Ikmi group employs interdisciplinary approaches to show how sea anemone ‘exercise’ changes their developing size and shape, uncovering an intimate relationship between behaviour and body development

SCIENCE & TECHNOLOGY

2022

sciencescience-technology

30 September 2021

New microscopy technique makes deep in vivo brain imaging possible

Scientists in EMBL’s Prevedel Group have developed a pioneering microscopy technique that allows researchers to observe cells hidden within opaque tissues, such as live neurons embedded deep in the brain.

SCIENCE & TECHNOLOGY

2021

sciencescience-technology

7 May 2021 Green streaks shoot off of a blue, purple and pink bulbous shape against a dark background of circles and curvy lines.