Structural biology of macromolecular protein-RNA complexes
ADAT2/3 structure bound to tRNA out in Nature Commincations. Structural basis for sequence-independent substrate selection by eukaryotic wobble base tRNA deaminase ADAT2/3. Dolce LG, Zimmer AA, Tengo L, Weis F, Rubio MAT, Alfonzo JD, Kowalinski E Nature communications, 2022…
Sequence-independent substrate selection by the eukaryotic wobble base deaminase ADAT2/3 involves multiple protein domains and distortion of the tRNA anticodon loop The essential deamination of adenosine A34 to inosine at the wobble base is the individual tRNA modification with the greatest effects…
Our group’s work on neglected tropical diseases has been highlighted in the new issue of the GIANT REVIEV, which is the magazine of Grenoble’s technology campus. Read on page 12 if you are interested!