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EMBL Imaging Centre

Open access to cutting-edge electron and light microscopy

We provide researchers from Europe and beyond with a synergistic portfolio of imaging services including cryo-EM, super-resolution and intravital microscopy to enable new ground-breaking research that crosses the scales of biology.

CLEM Sample Preparation

Vitrobot Mark IV

The Vitrobot Mark IV System from Thermo Fisher Scientific is an automated plunge freezer able to vitrify thin samples applied to an electron microscopy grid after removing excess fluid by blotting.

Features

  • Automated vitrification of aqueous suspensions and cells deposited on EM grids
  • Temperature and humidity-controlled environmental chamber

Specifications

  • Working temperature adjustable between +4°C and +60°C
  • Relative humidity adjustable to 100%

Credit: Stuart Ingham/EMBL.
Thermo Fisher Scientific Vitrobot Mark IV. Credit: Stuart Ingham/EMBL.

EM GP2

The EM GP2 from Leica Microsystems is an automated plunge freezer able to vitrify thin samples applied to an electron microscopy grid after removing excess fluid by blotting.

Features

  • Automated vitrification of aqueous suspensions and cells deposited on EM grids
  • Temperature and humidity-controlled environmental chamber
  • Sensor-driven blotting

Specifications

  • Working temperature adjustable between +4°C and +60°C
  • Relative humidity adjustable to 99%

Credit: Stuart Ingham/EMBL.
Leica EM GP2. Credit: Stuart Ingham/EMBL.

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