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Brain genome: regulation, evolution, and function – Course and Conference Office

EMBO | EMBL Symposium

Brain genome: regulation, evolution, and function

Overview

This conference will take place at EMBL Heidelberg, with the option to attend virtually. Please see EMBL’s COVID-19 safety recommendations if attending the on-site event.

Symposium overview

This symposium explores the many ways by which the genome is regulated in the brain in order to support neural function and plasticity. The extraordinary complexity of the brain places unique demands on the genome: How are several hundreds of different neural types specified by the same genetic instructions? Does the genome provide information that guides their connectivity? How is neural activity regulated by and how does it affect genome output? We will explore these fundamental questions from the standpoint of transcriptional regulation and chromatin-based processes, including but not limited to histone marks and variants, chromatin topology and folding, coding and noncoding RNAs, transposable elements, and DNA modifications.

The conference aims to bring together neuroscientists and experts in genome regulation. It will cover a broad range of experimental approaches and model systems, from biochemistry to single-cell genomics, from worms to human organoids. Overall, the conference will address the impact of genome regulation on unique features of the brain — its excitable nature, exquisite response to the environment and parallel processing capacity — with the longer-term vision of understanding how defective genome regulation can give rise to brain disease.

Session topics

  • Interplay between gene regulation and neuronal activity
  • Genomic regulation of brain plasticity and behaviour
  • Chromatin variations in the brain
  • From one genome to many neurons: neurodevelopment and neural diversity

Date: 25 - 28 Apr 2023

Location: EMBL Heidelberg and Virtual

Venue: EMBL Advanced Training Centre


Deadline(s):

Abstract submission: Closed

Registration (On-site): Closed

Registration (Virtual): Closed


Organisers:

  • Roberto Bonasio
    University of Pennsylvania, USA
    • Matthieu Boulard
      EMBL Rome, Italy

EMBL Courses and Conferences are kindly supported by our Corporate Partnership Programme

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