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Structural and Computational Biology

An embryo of the fruit fly Drosophila.

Predicting how gene expression varies

Discoveries at EMBL will help researchers to interpret one of the most common types of experiments in genomics and medical…

By Fabian Oswald

Science

EMBL spins the Sleeping Beauty transposase

New possibilities for gene…

By Mathias Jäger

Science
This image represents the integration of genomic, metabolic, proteomic, structural and cellular information about Mycoplasma pneumoniae in this project: one layer of an Electron Tomography scan of a bottle-shaped M. pneumoniae cell (grey) is overlaid with a schematic representation of this bacterium’s metabolism, where blue indicates interactions between proteins encoded in genes from the same functional unit. Apart from these expected interactions, the scientists found that, surprisingly, many proteins are multifunctional. For instance, there were various unexpected physical interactions (yellow lines) between proteins and the subunits that form the ribosome, which is depicted as an Electron microscopy image (yellow). Image credit: Takuji Yamada / EMBL

First-ever blueprint of a minimal cell is more complex than expected

What are the bare essentials of life, the indispensable ingredients required to produce a cell that can survive on its own? Can we describe the…

By Guest author(s)

Science

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