mahamid Archives

16 December 2024 Photo of Veijo Salo (on the left) holding and blowing into an illustrated bubble blower representing the protein seipin, whose structure is depicted three times on the right.

Photo of Veijo Salo (on the left) holding and blowing into an illustrated bubble blower representing the protein seipin, whose structure is depicted three times on the right.

Cute molecules and the scientists who adore them: Veijo Salo

Veijo Salo, postdoc at EMBL Heidelberg, talks about seipin, the cell’s molecular ‘bubble blower’.

PEOPLE & PERSPECTIVES

2024

people-perspectives

11 September 2024 Photographs of two scientists against a green-blue background.

New directions for molecular systems biology at EMBL

Julia Mahamid and Nassos Typas reflect on the direction of the Molecular Systems Biology Unit they now lead at EMBL Heidelberg.

PEOPLE & PERSPECTIVES

2024

people-perspectives

26 October 2023 Photographs of three scientists on a decorative blue background

EMBL scientists receive prestigious ERC Synergy Grants

Jan Kosinski, Julia Mahamid, and Georg Zeller have received grants to enable ambitious projects aimed at mapping the cellular protein synthesis machinery in context and understanding complex host-microbiome interactions, respectively.

EMBL ANNOUNCEMENTS

2023

embl-announcementsscience

4 July 2023 Photos of the three scientists elected as EMBO members on green background.

EMBL scientists elected to EMBO Membership

Three EMBL group leaders and six EMBL alumni were recognised for their contributions to the life sciences.

LAB MATTERS PEOPLE & PERSPECTIVES

2023

lab-matterspeople-perspectives

2 February 2023 Science illustration showing from left to right the progression from cryo-EM software to an annotated image of sub-cellular organelles, using a deep learning software.

Science illustration showing from left to right the progression from cryo-EM software to an annotated image of sub-cellular organelles, using a deep learning software.

AI helps scientists decipher cellular structures

New artificial intelligence tool adds speed and detailed cellular information to analysis of cryo-electron tomography to aid researchers’ understanding of inner cell workings.

2023

science

28 September 2022 3D structures of ribosomes are shown floating in a cellular space. A zoomed in portion shows an antibiotic molecule nested in a binding site on a ribosome.

3D structures of ribosomes are shown floating in a cellular space. A zoomed in portion shows an antibiotic molecule nested in a binding site on a ribosome.

Seeing antibiotics in action inside a pathogenic bacterium

New research by EMBL scientists shows at atomic detail how antibiotics affect the process of protein production inside bacteria.

SCIENCE & TECHNOLOGY

2022

sciencescience-technology

23 March 2022 Two Drosophila embryos stained with fluorescent dye on a purple background that indicates either solid or liquid state

From liquid to solid to drive development

Condensates are membraneless organelles that control specific functions within a cell. Scientists at EMBL Heidelberg have shown how the physical state of condensates can influence biological function.

SCIENCE & TECHNOLOGY

2022

sciencescience-technology

21 December 2021 A model of the doughnut-shaped nuclear pore complex. Individual molecules are marked in various colours.

Observing the secret life of molecules inside the cell

EMBL Hamburg’s Kosinski Group, the Beck Laboratory at the Max Planck Institute of Biophysics, and colleagues at EMBL Heidelberg recorded the nuclear pore complex contracting in living cells. They visualised the movement with an unprecedented level of detail with help of new software called…

SCIENCE & TECHNOLOGY

2021

sciencescience-technology

22 July 2021 Protein structural biology

Great expectations – the potential impacts of AlphaFold DB

A discussion of the applications that AlphaFold DB may enable and the possible impact of the resource on science and society.

SCIENCE & TECHNOLOGY

2021

sciencescience-technology

2 February 2021 A bacterial cell with the parts needed for information flow from DNA to messenger RNA to protein highlighted in different colours.

A bacterial cell with the parts needed for information flow from DNA to messenger RNA to protein highlighted in different colours.

The central dogma of molecular biology

This colourful image shows biological information flow in action: It’s a supramolecular assembly of DNA, RNA and proteins, observed directly inside a bacterial cell while turning genetic information into protein.

SCIENCE & TECHNOLOGY

2021

picture-of-the-weekscience-technology

7 December 2020 Female scientist stands in front of electron microscope that is taller than she is

Seeing deeper inside cells

While cryo-electron tomography (cryo-ET) was first envisioned in 1968, the advances the Mahamid group are bringing to this 3D method for studying molecules directly inside cells are new, and are likely to greatly expand its use.

SCIENCE & TECHNOLOGY

2020

sciencescience-technology

31 July 2020

This visual representation shows the newly identified architecture (left) of the coupled molecular machines responsible for transcription (green; DNA in magenta) and translation (blue and yellow), accompanied by the protein interaction network from mass spectrometry (centre) and the cryo-electron tomography data (right) from Mycoplasma pneumoniae that was used to model the structure. Credit: Liang Xue and Julia Mahamid/EMBL

Visualising the cell’s molecular machinery in action

A new approach that allows researchers to see molecular machinery at work inside cells has offered a deeper understanding of how bacteria produce proteins and a unique glimpse into how they respond to antibiotics.

SCIENCE & TECHNOLOGY

2020

sciencescience-technology

18 November 2019 Cryo-ET and micropatterning