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infectious disease

Year
20 December 2022

First linked dataset on Pathogens Portal

Updates from data resources The first  cohort study linking data across categories was recently added on the Pathogens Portal Cohort Browser and is also accessible from the BioSamples browser. This pilot study comes from Erasmus MC through the ReCoDID project, one of the COVID-19 Data Platform…

2022

updates-from-data-resources

15 October 2021 In the middle, there are two molecules of pUL21. One is blurred, to represent the molecule’s flexibility. In the background are two neuronal scenes. The one on the left is healthy and has a smooth surface. The one on the right is infected, which is represented by several green viral particles.

How herpes seizes proteins’ means of production

Science The Graham and Crump groups at the University of Cambridge and the Svergun Group at EMBL Hamburg have discovered a mechanism by which the herpes simplex virus takes control of the molecular machinery of human cells. Their work reveals how a dedicated viral protein hijacks key host proteins, forcing…

2021

science

25 May 2021 Microscope image of an engineered human blood vessel, featuring individual cells outlined in pink with blue nuclei.

Barriers against malaria

Picture of the week The Bernabeu Group aims to increase our knowledge of cerebral malaria, using in vitro engineered networks of human blood vessels and brain cells.

2021

picture-of-the-week

21 May 2021 Image of a mosquito on a clear surface

EMBL scientists support malaria research

Science EMBL scientists support research on malaria by providing freely available data resources and using innovative experimental approaches. Our Course and Conference Office facilitates the exchange of knowledge in the field by hosting the annual BioMalPar conference.

2021

science

2 December 2020 Curly-shaped trypanosomes, grey with bright specks of green fluorescent protein, against a grey background.

Tackling tropical diseases

Science Members of the EMBL community are working to improve our understanding of the parasites that cause malaria and sleeping sickness

2020

science

13 October 2020 Molecular structure of essential light chain protein in Plasmodium glideosome. The atoms connected by bonds are symbolised by short connected lines. They are surrounded by electrons – the electron density is depicted as shapes resembling clouds. Water molecules are visible in several places as red spots. The data used to create this 3D model were obtained using X-ray crystallography at Petra III beamline, at EMBL Hamburg.

How deadly parasites ‘glide’ into human cells

Science A group of scientists led by EMBL Hamburg’s Christian Löw provide insights into the molecular structure of proteins involved in the gliding movements through which the parasites causing malaria and toxoplasmosis invade human cells.

2020

science

8 June 2020 Microscopic image showing a macrophage that has been infected with Salmonella (green), causing cellular cathepsins (red) to locate to the nucels (blue).

Re-trafficking proteins to fight Salmonella infections

Science Scientists including members of EMBL’s Typas group have investigated how immune cells called macrophages respond to infection by the intracellular pathogen Salmonella enterica. They discovered that Salmonella causes newly produced cathepsins to accumulate in the nuclei of infected cells to…

2020

science

24 April 2020 Collage of images representing wet and dry lab research and healthcare

Why share data during a pandemic?

Science In March 2020, planes were grounded, streets went quiet, and our lives changed forever. But while the world came to a halt, many scientists were ramping up their efforts to understand the new virus.

2020

science

26 September 2019 The Old Port of Marseille.

EMBL and Tara: Marseille

Events From 27–30 September, Tara will be docked in the port of Marseille, France’s second largest city.

2019

events

4 May 2008

Getting wise to the influenza virus’ tricks

Science Influenza is currently a grave concern for governments and health organisations around the world. Now one of the tactics used by influenza virus to take over the machinery of infected cells has been laid bare by structural biologists at the EMBL, the joint Unit of Virus Host-Cell Interaction of…

2008

science

22 June 2007

New compound effectively treats fungal infections

Science A new mechanism to attack hard-to-treat fungal infections has been revealed by scientists from the biotech company Anacor Pharmaceuticals Inc., California, and the European Molecular Biology Laboratory [EMBL] outstation in Grenoble, France. In the current issue of Science they describe…

2007

science

25 February 2007

A first glimpse of the influenza replication machine

Science In 1918, 50 million people died during a worldwide influenza pandemic caused by mutation of a bird-specific strain of the influenza virus. Recently H5N1, another highly infectious avian strain has caused outbreaks of bird flu around the world. There is great concern that this virus might also…

2007

science

12 February 2007

A signal that protects the liver from hepatitis and cancer

Science Liver cancer is one of the deadliest cancers worldwide; every year sees more than 400,000 new cases, and most of the victims die in less than one year. Despite extensive research, the underlying molecular mechanisms of the disease are poorly understood. A new study by researchers from the Mouse…

2007

science

5 April 2006

With joint forces against Malaria

Events Today the network of excellence for Biology and Pathology of the Malaria Parasite (BioMalPar), will bring together the world’s elite in the field of Malaria research at the European Molecular Biology Laboratory (EMBL) in Heidelberg. At the second annual BioMalPar conference, organised jointly…

2006

events

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