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18 September 2024 An open book with its pages showing the image of overlapping strands of DNA with nucleosomes. There are small sticky notes on the pages indicating annotations.

An open book with its pages showing the image of overlapping strands of DNA with nucleosomes. There are small sticky notes on the pages indicating annotations.

Silencing in action: how cells ‘repress’ genomic remnants of ancient viruses

Science & Technology Researchers have identified key cellular control sites that regulate gene expression and prevent the activation of ancient viral sequences in the genome.

2024

science-technology

30 September 2009

In the centre, a structural model determined by X-ray crystallography shows how the two tags (attached to a short section of the histone protein – all in cyan) fit neatly into the Brdt pocket (purple). In the background image, hypercompaction by Brdt causes relatively diffuse chromatin (stained blue inside the nuclei of two cells on the top left) to compact and clump together (two on the bottom right).

Putting the squeeze on sperm DNA

Science & Technology In the quest for speed, olympic swimmers shave themselves or squeeze into high-tech super-suits. In the body, sperm are the only cells that swim and, as speed is crucial to fertility, have developed their own ways to become exceptionally streamlined. Scientists at the European Molecular Biology…

2009

sciencescience-technology

19 June 2005

A link between our body’s energy levels and a protein that wraps our DNA?

Science & Technology Living organisms need to sense the amount of energy that is available to them and regulate the activity of their genes accordingly. Scientists have made the unexpected finding that a histone protein, which wraps DNA into tight bundles and regulates gene activity, can bind a small molecule produced…

2005

sciencescience-technology

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