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Hackett

epigenetic reprogramming, epigenetic memory, Hackett group

Unravelling epigenetic reprogramming

A study conducted by the Hackett group at EMBL Rome has identified key factors controlling the complex system of gene regulation during early embryo development, shedding new light on the mechanisms behind these events and on their evolutionary implications. Their findings are published in Nature…

By Rossana De Lorenzi

Science

Scientists in the Hackett group at EMBL Rome doing lab work

Silencing the SARS-CoV-2 receptor with epigenetic modifications

EMBL scientists develop a new molecular tool to prevent SARS-CoV-2 infection in mice. This tool is able to cause targeted epigenetic modifications of specific genes in specific cell populations. They will use it in mice to target airway cells that express the ACE2 protein – the receptor that…

By Rossana De Lorenzi

Science

Artist's representation of double helix next to black mouse.

Deleting genes to study how germ cells are born

How embryonic stem cells develop into the germ line

By Patrick Mueller

Science

Welcome: Jamie Hackett

Meet Monterotondo’s new group leader for epigenetic reprogramming and inheritance, Jamie Hackett

By Annika Duda

Science

Embryos use ancient viral DNA

EMBL scientists detect important function of genetic sequence our ancestors assimilated from a virus

By Annika Duda

Science

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