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21 August 2024 Three images of the cell at different stages of mitosis. In the left: round navy shape and irregular thick magenta line within it. In the middle: the same round shape with two irregular magenta shapes. On the right: Two round navy shapes connected with each other. Each of them holds shiny magenta-yellow clusters.

The forces behind chromosome repulsion and attraction during cell division

Science & Technology EMBL Heidelberg researchers discovered how a protein switches between repelling and gluing chromosomes during cell division. This helps the mother cell to divide the genome equally into two daughter cells and cluster chromosomes inside the daughter nuclei, ensuring a successful cell division.

2024

science-technology

21 January 2022 The cross-section of a cell expressing a green fluorescently tagged protein and illuminated by a blue laser is visible in the foreground, surrounded by a vortex of cells

Cell sorting enters a new dimension

Science & Technology EMBL researchers, in collaboration with BD Biosciences, have demonstrated a new technology that allows rapid image-based sorting of cells. The new technology represents a major upgrade to flow cytometry and has applications in diverse life science fields.

2022

sciencescience-technology

17 June 2011 Condensin loops around several strands of DNA, keeping it coiled up and easier to transport. (Artistic impression) Image credits: EMBL/ P. Riedinger

Keeping it together

As any rock-climber knows, trailing a long length of rope behind you is not easy. A dangling length of rope is unwieldy and hard to manoeuvre, and can get tangled up or stuck on an outcropping. Cells face the same problem when dragging chromosomes apart during cell division. The chromosomes are…

2011

science

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