cell reprogramming

2 July 2020 epigenetic reprogramming, epigenetic memory, Hackett group

Unravelling epigenetic reprogramming

Science, Science & Technology A study conducted by the Hackett group at EMBL Rome has identified key factors controlling the complex system of gene regulation during early embryo development, shedding new light on the mechanisms behind these events and on their evolutionary implications. Their findings are published in Nature…



10 December 2009 These microscopy images show the cellular reprogramming uncovered by EMBL scientists. On the left is an ovary of a normal adult female mouse, with a close-up (top left) showing the typical female granulosa cells. When the Foxl2 gene was silenced in these cells (right, top right: close-up), they took on the characteristics of Sertoli cells, the cells normally found in testes of male mice. Image credit: Treier / EMBL

The Battle of the Sexes

Science Is it a boy or a girl? Expecting parents may be accustomed to this question, but contrary to what they may think, the answer doesn’t depend solely on their child’s sex chromosomes. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany and the Medical Research…



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