Critical points and transitions in embryo development
Our new paper is out in Nature Physics! This work focuses on how different control parameters regulate different types of tissue phase transitions, which in turn affect tissue organisation. By uncoupling transitions that are cell density- and cell-cell-adhesion-dependent, this work demonstrates that the adhesion serves as a main parameter that drives the tissue solidification and, when uncoupled from the cell density, leads to lumen formation. You can also read more from the research briefing here.
Additionally, the image illustrating the work (mosaic degradation of cell-cell adhesion leading to the solid-like state in one part of the embryo and fluid-like in another) was selected as the cover of Nature Physics’ new issue!