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Electron Microscopy Core Facility

The facility provides advanced expertise in electron microscopy, from sample preparation to image analysis, for a wide variety of biological samples.

Publications

A high throughput SEC23 functional interaction screen reveals a role for focal adhesion and extracellular matrix signalling in the regulation of COPII subunit SEC23A

Jung J, Khan MM, Landry J, Halavatyi A, Machado P, Reiss M, Pepperkok R

2021

doi:10.1101/2021.03.16.435679.

Fluorescence-based 3D targeting of FIB-SEM acquisition of small volumes in large samples.

Ronchi P, Machado P, D’Imprima E, Mizzon G, Best BT, Cassella L, Schnorrenberg S, Montero MG, Jechlinger M, Ephrussi A, Leptin M, Mahamid J, Schwab Y

2021

doi:10.1101/2021.01.18.427072.

Integrative imaging reveals SARS-CoV-2-induced reshaping of subcellular morphologies.

Cortese M, Lee JY, Cerikan B, Neufeldt CJ, Oorschot VMJ, Köhrer S, Hennies J, Schieber NL, Ronchi P, Mizzon G, Romero-Brey I, Santarella-Mellwig R, Schorb M, Boermel M, Mocaer K, Beckwith MS, Templin RM, Gross V, Pape C, Tischer C, Frankish J, Horvat NK, Laketa V, Stanifer M, Boulant S, Ruggieri A, Chatel-Chaix L, Schwab Y, Bartenschlager R

Cell host & microbe 2020

33245857. doi:10.1016/j.chom.2020.11.003.

Single cell polarity in liquid phase facilitates tumour metastasis.

Lorentzen A, Becker PF, Kosla J, Saini M, Weidele K, Ronchi P, Klein C, Wolf MJ, Geist F, Seubert B, Ringelhan M, Mihic-Probst D, Esser K, Roblek M, Kuehne F, Bianco G, O'Connor T, Müller Q, Schuck K, Lange S, Hartmann D, Spaich S, Groß O, Utikal J, Haferkamp S, Sprick MR, Damle-Vartak A, Hapfelmeier A, Hüser N, Protzer U, Trumpp A, Saur D, Vartak N, Klein CA, Polzer B, Borsig L, Heikenwalder M

Nature communications 2018

29491397. doi:10.1038/s41467-018-03139-6.


A high throughput SEC23 functional interaction screen reveals a role for focal adhesion and extracellular matrix signalling in the regulation of COPII subunit SEC23A

Jung J, Khan MM, Landry J, Halavatyi A, Machado P, Reiss M, Pepperkok R

2021

doi:10.1101/2021.03.16.435679.

Fluorescence-based 3D targeting of FIB-SEM acquisition of small volumes in large samples.

Ronchi P, Machado P, D’Imprima E, Mizzon G, Best BT, Cassella L, Schnorrenberg S, Montero MG, Jechlinger M, Ephrussi A, Leptin M, Mahamid J, Schwab Y

2021

doi:10.1101/2021.01.18.427072.

Integrative imaging reveals SARS-CoV-2-induced reshaping of subcellular morphologies.

Cortese M, Lee JY, Cerikan B, Neufeldt CJ, Oorschot VMJ, Köhrer S, Hennies J, Schieber NL, Ronchi P, Mizzon G, Romero-Brey I, Santarella-Mellwig R, Schorb M, Boermel M, Mocaer K, Beckwith MS, Templin RM, Gross V, Pape C, Tischer C, Frankish J, Horvat NK, Laketa V, Stanifer M, Boulant S, Ruggieri A, Chatel-Chaix L, Schwab Y, Bartenschlager R

Cell host & microbe 2020

33245857. doi:10.1016/j.chom.2020.11.003.

Single cell polarity in liquid phase facilitates tumour metastasis.

Lorentzen A, Becker PF, Kosla J, Saini M, Weidele K, Ronchi P, Klein C, Wolf MJ, Geist F, Seubert B, Ringelhan M, Mihic-Probst D, Esser K, Roblek M, Kuehne F, Bianco G, O'Connor T, Müller Q, Schuck K, Lange S, Hartmann D, Spaich S, Groß O, Utikal J, Haferkamp S, Sprick MR, Damle-Vartak A, Hapfelmeier A, Hüser N, Protzer U, Trumpp A, Saur D, Vartak N, Klein CA, Polzer B, Borsig L, Heikenwalder M

Nature communications 2018

29491397. doi:10.1038/s41467-018-03139-6.

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