Publications – Electron Microscopy Core Facility

Profiling cellular diversity in sponges informs animal cell type and nervous system evolution.

Musser JM, Schippers KJ, Nickel M, Mizzon G, Kohn AB, Pape C, Ronchi P, Papadopoulos N, Tarashansky AJ, Hammel JU, Wolf F, Liang C, Hernández-Plaza A, Cantalapiedra CP, Achim K, Schieber NL, Pan L, Ruperti F, Francis WR, Vargas S, Kling S, Renkert M, Polikarpov M, Bourenkov G, Feuda R, Gaspar I, Burkhardt P, Wang B, Bork P, Beck M, Schneider TR, Kreshuk A, Wörheide G, Huerta-Cepas J, Schwab Y, Moroz LL, Arendt D

Science (New York, N.Y.), 2021

doi:10.1126/science.abj2949.

Subcellular architecture and metabolic connection in the planktonic photosymbiosis between Collodaria (radiolarians) and their microalgae.

Decelle J, Veronesi G, LeKieffre C, Gallet B, Chevalier F, Stryhanyuk H, Marro S, Ravanel S, Tucoulou R, Schieber N, Finazzi G, Schwab Y, Musat N

Environmental microbiology, 2021

doi:10.1111/1462-2920.15766.

High-precision targeting workflow for volume electron microscopy.

Ronchi P, Mizzon G, Machado P, D'Imprima E, Best BT, Cassella L, Schnorrenberg S, Montero MG, Jechlinger M, Ephrussi A, Leptin M, Mahamid J, Schwab Y

The Journal of cell biology, 2021

doi:10.1083/jcb.202104069.

Whole-body integration of gene expression and single-cell morphology.

Vergara HM, Pape C, Meechan KI, Zinchenko V, Genoud C, Wanner AA, Mutemi KN, Titze B, Templin RM, Bertucci PY, Simakov O, Dürichen W, Machado P, Savage EL, Schermelleh L, Schwab Y, Friedrich RW, Kreshuk A, Tischer C, Arendt D

Cell, 2021

doi:10.1016/j.cell.2021.07.017.

Cytoklepty in the plankton: a host strategy to optimize the bioenergetic machinery of endosymbiotic algae.

Uwizeye C, Mars Brisbin M, Gallet B, Chevalier F, LeKieffre C, Schieber NL, Falconet D, Wangpraseurt D, Schertel L, Stryhanyuk H, Musat N, Mitarai S, Schwab Y, Finazzi G, Decelle J

Proceedings of the National Academy of Sciences of the United States of America, 2021

doi:10.1073/pnas.2025252118.

Liver sinusoidal endothelial cells suppress BMP2 production in response to TGFβ pathway activation.

Colucci S, Altamura S, Marques O, Dropmann A, Horvat NK, Müdder K, Hammad S, Dooley S, Muckenthaler MU

Hepatology (Baltimore, Md.), 2021

doi:10.1002/hep.31900.

Recapitulating actin module organization in the Drosophila reveals new roles for bristle-actin-modulating proteins.

Krishnan RK, Baskar R, Anna B, Elia N, Boermel M, Bausch AR, Abdu U

International journal of molecular sciences, 2021

doi:10.3390/ijms22084006.

Morphological bases of phytoplankton energy management and physiological responses unveiled by 3D subcellular imaging.

Uwizeye C, Decelle J, Jouneau PH, Flori S, Gallet B, Keck JB, Bo DD, Moriscot C, Seydoux C, Chevalier F, Schieber NL, Templin R, Allorent G, Courtois F, Curien G, Schwab Y, Schoehn G, Zeeman SC, Falconet D, Finazzi G

Nature communications, 2021

doi:10.1038/s41467-021-21314-0.

Mesopolysaccharides: the extracellular surface layer of visceral organs.

Wagner WL, Zheng Y, Pierce A, Ackermann M, Horstmann H, Kuner T, Ronchi P, Schwab Y, Konietzke P, Wünnemann F, Wielpütz MO, Kauczor HU, Mentzer SJ

PloS one, 2020

doi:10.1371/journal.pone.0238798.

Photonic-chip assisted correlative light and electron microscopy.

Tinguely JC, Steyer AM, Øie CI, Helle ØI, Dullo FT, Olsen R, McCourt P, Schwab Y, Ahluwalia BS

Communications biology, 2020

doi:10.1038/s42003-020-01473-4.

Local blood coagulation drives cancer cell arrest and brain metastasis in a mouse model.

Feinauer MJ, Schneider SW, Berghoff AS, Robador JR, Tehranian C, Karreman MA, Venkataramani V, Solecki G, Grosch JK, Gunkel K, Kovalchuk B, Mayer FT, Fischer M, O Breckwoldt M, Brune M, Schwab Y, Wick W, Bauer AT, Winkler F

Blood, 2020

doi:10.1182/blood.2020005710.

Integrative imaging reveals SARS-CoV-2-induced reshaping of subcellular morphologies.

Cortese M, Lee JY, Cerikan B, Neufeldt CJ, Oorschot VMJ, Köhrer S, Hennies J, Schieber NL, Ronchi P, Mizzon G, Romero-Brey I, Santarella-Mellwig R, Schorb M, Boermel M, Mocaer K, Beckwith MS, Templin RM, Gross V, Pape C, Tischer C, Frankish J, Horvat NK, Laketa V, Stanifer M, Boulant S, Ruggieri A, Chatel-Chaix L, Schwab Y, Bartenschlager R

Cell host & microbe, 2020

doi:10.1016/j.chom.2020.11.003.

In-cell architecture of the nuclear pore and snapshots of its turnover.

Allegretti M, Zimmerli CE, Rantos V, Wilfling F, Ronchi P, Fung HKH, Lee CW, Hagen W, Turoňová B, Karius K, Börmel M, Zhang X, Müller CW, Schwab Y, Mahamid J, Pfander B, Kosinski J, Beck M

Nature, 2020

doi:10.1038/s41586-020-2670-5.

Spatial control of nucleoporin condensation by fragile X-related proteins.

Agote-Aran A, Schmucker S, Jerabkova K, Jmel Boyer I, Berto A, Pacini L, Ronchi P, Kleiss C, Guerard L, Schwab Y, Moine H, Mandel JL, Jacquemont S, Bagni C, Sumara I

The EMBO journal, 2020

doi:10.15252/embj.2020104467.

Molecular determinants of large cargo transport into the nucleus.

Paci G, Zheng T, Caria J, Zilman A, Lemke EA

eLife, 2020

doi:10.7554/eLife.55963.

Transcytosis via the late endocytic pathway as a cell morphogenetic mechanism.

Mathew R, Rios-Barrera LD, Machado P, Schwab Y, Leptin M

The EMBO journal, 2020

doi:10.15252/embj.2020105332.

TEM bright field imaging of thick specimens: nodes in Thon ring patterns.

Tichelaar W, Hagen WJH, Gorelik TE, Xue L, Mahamid J

Ultramicroscopy, 2020

doi:10.1016/j.ultramic.2020.113023.

Selective autophagy degrades nuclear pore complexes.

Lee CW, Wilfling F, Ronchi P, Allegretti M, Mosalaganti S, Jentsch S, Beck M, Pfander B

Nature cell biology, 2020

doi:10.1038/s41556-019-0459-2.

Dynamic buffering of extracellular chemokine by a dedicated scavenger pathway enables robust adaptation during directed tissue migration.

Wong M, Newton LR, Hartmann J, Hennrich ML, Wachsmuth M, Ronchi P, Guzmán-Herrera A, Schwab Y, Gavin AC, Gilmour D

Developmental cell, 2020

doi:10.1016/j.devcel.2020.01.013.

Cell and tissue manipulation with ultrashort infrared laser pulses in light-sheet microscopy.

de Medeiros G, Kromm D, Balazs B, Norlin N, Günther S, Izquierdo E, Ronchi P, Komoto S, Krzic U, Schwab Y, Peri F, de Renzis S, Leptin M, Rauzi M, Hufnagel L

Scientific reports, 2020

doi:10.1038/s41598-019-54349-x.

AMST: Alignment to median smoothed template for focused ion beam scanning electron microscopy image stacks.

Hennies J, Lleti JMS, Schieber NL, Templin RM, Steyer AM, Schwab Y

Scientific reports, 2020

doi:10.1038/s41598-020-58736-7.

Actin assembly ruptures the nuclear envelope by prying the lamina away from nuclear pores and nuclear membranes in starfish oocytes.

Wesolowska N, Avilov I, Machado P, Geiss C, Kondo H, Mori M, Lenart P

eLife, 2020

doi:10.7554/eLife.49774.

Drosophila Atg9 regulates the actin cytoskeleton via interactions with profilin and Ena.

Kiss V, Jipa A, Varga K, Takáts S, Maruzs T, Lőrincz P, Simon-Vecsei Z, Szikora S, Földi I, Bajusz C, Tóth D, Vilmos P, Gáspár I, Ronchi P, Mihály J, Juhász G

Cell death and differentiation, 2019

doi:10.1038/s41418-019-0452-0.

Tunneling nanotube-mediated intercellular vesicle and protein transfer in the stroma-provided imatinib resistance in chronic myeloid leukemia cells.

Kolba MD, Dudka W, Zaręba-Kozioł M, Kominek A, Ronchi P, Turos L, Chroscicki P, Wlodarczyk J, Schwab Y, Klejman A, Cysewski D, Srpan K, Davis DM, Piwocka K

Cell death & disease, 2019

doi:10.1038/s41419-019-2045-8.

Nuclear pores assemble from Nucleoporin condensates during oogenesis.

Hampoelz B, Schwarz A, Ronchi P, Bragulat-Teixidor H, Tischer C, Gaspar I, Ephrussi A, Schwab Y, Beck M

Cell, 2019

doi:10.1016/j.cell.2019.09.022.

Lysosomal degradation of newly formed insulin granules contributes to β cell failure in diabetes.

Pasquier A, Vivot K, Erbs E, Spiegelhalter C, Zhang Z, Aubert V, Liu Z, Senkara M, Maillard E, Pinget M, Kerr-Conte J, Pattou F, Marciniak G, Ganzhorn A, Ronchi P, Schwab Y, Schieber NL, Goginashvili A, Saftig P, Ricci R

Nature communications, 2019

doi:10.1038/s41467-019-11170-4.

Spatiotemporal coupling of the hepatitis C virus replication cycle by creating a lipid droplet-proximal membranous replication compartment.

Lee JY, Cortese M, Haselmann U, Tabata K, Romero-Brey I, Funaya C, Schieber NL, Qiang Y, Bartenschlager M, Kallis S, Ritter C, Rohr K, Schwab Y, Ruggieri A, Bartenschlager R

Cell reports, 2019

doi:10.1016/j.celrep.2019.05.063.

Software tools for automated transmission electron microscopy.

Schorb M, Haberbosch I, Hagen WJH, Schwab Y, Mastronarde DN

Nature methods, 2019

doi:10.1038/s41592-019-0396-9.

Algal remodeling in a ubiquitous planktonic photosymbiosis.

Decelle J, Stryhanyuk H, Gallet B, Veronesi G, Schmidt M, Balzano S, Marro S, Uwizeye C, Jouneau PH, Lupette J, Jouhet J, Maréchal E, Schwab Y, Schieber NL, Tucoulou R, Finazzi G, Richnow H, Musat N

Current biology : CB, 2019

doi:10.1016/j.cub.2019.01.073.

Clearance by microglia depends on packaging of phagosomes into a unique cellular compartment.

Villani A, Benjaminsen J, Moritz C, Henke K, Hartmann J, Norlin N, Richter K, Schieber NL, Franke T, Schwab Y, Peri F

Developmental cell, 2019

doi:10.1016/j.devcel.2019.02.014.

Studying the fate of tumor extracellular vesicles at high spatiotemporal resolution using the zebrafish embryo.

Hyenne V, Ghoroghi S, Collot M, Bons J, Follain G, Harlepp S, Mary B, Bauer J, Mercier L, Busnelli I, Lefebvre O, Fekonja N, Garcia-Leon MJ, Machado P, Delalande F, Silva SG, López AA, van Niel G, Verweij FJ, Peinado H, Djouad F, Klymchenko AS, Carapito C, Goetz JG

Developmental cell, 2019

doi:10.1016/j.devcel.2019.01.014.

GM130 and p115 play a key role in the organisation of the early secretory pathway during skeletal muscle differentiation.

Giacomello E, Ronchi P, Pepperkok R

Journal of cell science, 2019

doi:10.1242/jcs.222083.

Alpha-synuclein fibrils recruit TBK1 and OPTN to lysosomal damage sites and induce autophagy in microglial cells.

Bussi C, Peralta Ramos JM, Arroyo DS, Gallea JI, Ronchi P, Kolovou A, Wang JM, Florey O, Celej MS, Schwab Y, Ktistakis NT, Iribarren P

Journal of cell science, 2018

doi:10.1242/jcs.226241.

Altered nuclear envelope structure and proteasome function of micronuclei.

Maass KK, Rosing F, Ronchi P, Willmund KV, Devens F, Hergt M, Herrmann H, Lichter P, Ernst A

Experimental cell research, 2018

doi:10.1016/j.yexcr.2018.08.029.

Correlative light electron microscopy (CLEM) for tracking and imaging viral protein associated structures in cryo-immobilized cells.

Santarella-Mellwig R, Haselmann U, Schieber NL, Walther P, Schwab Y, Antony C, Bartenschlager R, Romero-Brey I

Journal of visualized experiments : JoVE, 2018

doi:10.3791/58154.

Correlated light and electron microscopy of cell division in large marine oocytes, eggs, and embryos.

Burdyniuk M, Wesolowska N, Fleszar M, Karreman MA, Machado P, Borrego-Pinto J, Ruthensteiner B, Schwab Y, Lénárt P

Methods in cell biology, 2018

doi:10.1016/bs.mcb.2018.03.031.

Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction.

Weinhard L, di Bartolomei G, Bolasco G, Machado P, Schieber NL, Neniskyte U, Exiga M, Vadisiute A, Raggioli A, Schertel A, Schwab Y, Gross CT

Nature communications, 2018

doi:10.1038/s41467-018-03566-5.

Single cell polarity in liquid phase facilitates tumour metastasis.

Lorentzen A, Becker PF, Kosla J, Saini M, Weidele K, Ronchi P, Klein C, Wolf MJ, Geist F, Seubert B, Ringelhan M, Mihic-Probst D, Esser K, Roblek M, Kuehne F, Bianco G, O'Connor T, Müller Q, Schuck K, Lange S, Hartmann D, Spaich S, Groß O, Utikal J, Haferkamp S, Sprick MR, Damle-Vartak A, Hapfelmeier A, Hüser N, Protzer U, Trumpp A, Saur D, Vartak N, Klein CA, Polzer B, Borsig L, Heikenwalder M

Nature communications, 2018

doi:10.1038/s41467-018-03139-6.

Postmitotic nuclear pore assembly proceeds by radial dilation of small membrane openings

Otsuka S, Steyer AM, Schorb M, Hériché JK, Hossain MJ, Sethi S, Kueblbeck M, Schwab Y, Beck M, Ellenberg J

Nature Structural and Molecular Biology, 2017

doi:10.1038/s41594-017-0001-9.

Membrane alterations induced by nonstructural proteins of human norovirus.

Doerflinger SY, Cortese M, Romero-Brey I, Menne Z, Tubiana T, Schenk C, White PA, Bartenschlager R, Bressanelli S, Hansman GS, Lohmann V

PLoS pathogens, 2017

doi:10.1371/journal.ppat.1006705.

Asymmetric Centriole Numbers at Spindle Poles Cause Chromosome Missegregation in Cancer.

Cosenza MR, Cazzola A, Rossberg A, Schieber NL, Konotop G, Bausch E, Slynko A, Holland-Letz T, Raab MS, Dubash T, Glimm H, Poppelreuther S, Herold-Mende C, Schwab Y, Krämer A

Cell reports, 2017

doi:10.1016/j.celrep.2017.08.005.

Exosomes purified from a single cell type have diverse morphology.

Zabeo D, Cvjetkovic A, Lässer C, Schorb M, Lötvall J, Höög JL

Journal of extracellular vesicles, 2017

doi:10.1080/20013078.2017.1329476.

Find your way with X-Ray: Using microCT to correlate in vivo imaging with 3D electron microscopy.

Karreman MA, Ruthensteiner B, Mercier L, Schieber NL, Solecki G, Winkler F, Goetz JG, Schwab Y

Methods in cell biology, 2017

doi:10.1016/bs.mcb.2017.03.006.

Immune protection against reinfection with nonprimate hepacivirus.

Pfaender S, Walter S, Grabski E, Todt D, Bruening J, Romero-Brey I, Gather T, Brown RJ, Hahn K, Puff C, Pfankuche VM, Hansmann F, Postel A, Becher P, Thiel V, Wagner B, Kalinke U, Baumgärtner W, Bartenschlager R, Pietschmann T, Feige K, Steinmann E, Cavalleri JM

Proceedings of the National Academy of Sciences of the United States of America, 2017

doi:10.1073/pnas.1619380114.

Matrix MAPS-an intuitive software to acquire, analyze, and annotate light microscopy data for CLEM.

Schorb M, Sieckmann F

Methods in cell biology, 2017

doi:10.1016/bs.mcb.2017.03.012.

In vivo testing of gold nanoparticles using the Caenorhabditis elegans model organism.

Gonzalez-Moragas L, Berto P, Vilches C, Quidant R, Kolovou A, Santarella-Mellwig R, Schwab Y, Stürzenbaum S, Roig A, Laromaine A

Acta biomaterialia, 2017

doi:10.1016/j.actbio.2017.01.080.

A new method for cryo-sectioning cell monolayers using a correlative workflow.

Kolovou A, Schorb M, Tarafder A, Sachse C, Schwab Y, Santarella-Mellwig R

Methods in cell biology, 2017

doi:10.1016/bs.mcb.2017.03.011.

Minimal resin embedding of multicellular specimens for targeted FIB-SEM imaging.

Schieber NL, Machado P, Markert SM, Stigloher C, Schwab Y, Steyer AM

Methods in cell biology, 2017

doi:10.1016/bs.mcb.2017.03.005.

Ultrastructural Characterization of Zika Virus Replication Factories.

Cortese M, Goellner S, Acosta EG, Neufeldt CJ, Oleksiuk O, Lampe M, Haselmann U, Funaya C, Schieber N, Ronchi P, Schorb M, Pruunsild P, Schwab Y, Chatel-Chaix L, Ruggieri A, Bartenschlager R

Cell reports, 2017

doi:10.1016/j.celrep.2017.02.014.

New hardware and workflows for semi-automated correlative cryo-fluoresence and cryo-electron microscopy/tomography.

Schorb M, Gaechter L, Avinoam O, Sieckmann F, Clarke M, Bebeacua C, Bykov YS, Sonnen AF, Lihl R, Briggs JA

Journal of structural biology, 2016

doi:10.1016/j.jsb.2016.06.020.

Analysis of cytokinesis by electron microscopy.

König J, Borrego-Pinto J, Streichert D, Munzig M, Lenart P, Müller-Reichert T

Methods in cell biology, 2016

doi:10.1016/bs.mcb.2016.03.029.

Bio-identity and fate of albumin-coated SPIONs evaluated in cells and by the C. elegans model.

Yu SM, Gonzalez-Moragas L, Milla M, Kolovou A, Mellwig-Santarella R, Schwab Y, Laromaine A, Roig A

Acta Biomaterialia, 2016

doi:10.1016/j.actbio.2016.07.024.

Nuclear pore assembly proceeds by an inside-out extrusion of the nuclear envelope

Otsuka S, Bui KH, Schorb M, Hossain MJ, Politi AZ, Koch B, Eltsov M, Beck M, Ellenberg J

eLife, 2016

doi:10.7554/eLife.19071.

Dengue virus perturbs mitochondrial morphodynamics to dampen innate immune responses.

Chatel-Chaix L, Cortese M, Romero-Brey I, Bender S, Neufeldt CJ, Fischl W, Scaturro P, Schieber N, Schwab Y, Fischer B, Ruggieri A, Bartenschlager R

Cell host & microbe, 2016

doi:10.1016/j.chom.2016.07.008.

Pre-assembled nuclear pores insert into the nuclear envelope during early development.

Hampoelz B, Mackmull MT, Machado P, Ronchi P, Bui KH, Schieber N, Santarella-Mellwig R, Necakov A, Andrés-Pons A, Philippe JM, Lecuit T, Schwab Y, Beck M

Cell, 2016

doi:10.1016/j.cell.2016.06.015.

Higher-order assemblies of oligomeric cargo receptor complexes form the membrane scaffold of the Cvt vesicle.

Bertipaglia C, Schneider S, Jakobi AJ, Tarafder AK, Bykov YS, Picco A, Kukulski W, Kosinski J, Hagen WJ, Ravichandran AC, Wilmanns M, Kaksonen M, Briggs JA, Sachse C

EMBO reports, 2016

doi:10.15252/embr.201541960.

Clathrin modulates vesicle scission, but not invagination shape, in yeast endocytosis.

Kukulski W, Picco A, Specht T, Briggs JA, Kaksonen M

eLife, 2016

doi:10.7554/elife.16036.

ESCRT-III drives the final stages of CUPS maturation for unconventional protein secretion.

Curwin AJ, Brouwers N, Adell MA, Teis D, Turacchio G, Parashuraman S, Ronchi P, Malhotra V

eLife, 2016

doi:10.7554/elife.16299.

Transmembrane protein TMEM170A is a newly discovered regulator of ER and nuclear envelope morphogenesis in human cells.

Christodoulou A, Santarella-Mellwig R, Santama N, Mattaj IW

Journal of cell science, 2016

doi:10.1242/jcs.175273.

Molecular architecture of the inner ring scaffold of the human nuclear pore complex.

Kosinski J, Mosalaganti S, von Appen A, Teimer R, DiGuilio AL, Wan W, Bui KH, Hagen WJ, Briggs JA, Glavy JS, Hurt E, Beck M

Science (New York, N.Y.), 2016

doi:10.1126/science.aaf0643.

Distinct mechanisms eliminate mother and daughter centrioles in meiosis of starfish oocytes.

Borrego-Pinto J, Somogyi K, Karreman MA, König J, Müller-Reichert T, Bettencourt-Dias M, Gönczy P, Schwab Y, Lénárt P

The Journal of cell biology, 2016

doi:10.1083/jcb.201510083.

Fast and precise targeting of single tumor cells in vivo by multimodal correlative microscopy.

Karreman MA, Mercier L, Schieber NL, Solecki G, Allio G, Winkler F, Ruthensteiner B, Goetz JG, Schwab Y

Journal of cell science, 2015

doi:10.1242/jcs.181842.

Viral infection at high magnification: 3D electron microscopy methods to analyze the architecture of infected cells.

Romero-Brey I, Bartenschlager R

Viruses, 2015

doi:10.3390/v7122940.

Endocytic membrane turnover at the leading edge is driven by a transient interaction between Cdc42 and GRAF1.

Francis MK, Holst MR, Vidal-Quadras M, Henriksson S, Santarella-Mellwig R, Sandblad L, Lundmark R

Journal of cell science, 2015

doi:10.1242/jcs.174417.

Soraphen A: A broad-spectrum antiviral natural product with potent anti-hepatitis C virus activity.

Koutsoudakis G, Romero-Brey I, Berger C, Pérez-Vilaró G, Monteiro Perin P, Vondran FW, Kalesse M, Harmrolfs K, Müller R, Martinez JP, Pietschmann T, Bartenschlager R, Brönstrup M, Meyerhans A, Díez J

Journal of hepatology, 2015

doi:10.1016/j.jhep.2015.06.002.

Interferon-inducible cholesterol-25-hydroxylase restricts hepatitis C virus replication through blockage of membranous web formation.

Anggakusuma, Romero-Brey I, Berger C, Colpitts CC, Boldanova T, Engelmann M, Todt D, Perin PM, Behrendt P, Vondran FW, Xu S, Goffinet C, Schang LM, Heim MH, Bartenschlager R, Steinmann E, Pietschmann T

Hepatology (Baltimore, Md.), 2015

doi:10.1002/hep.27913.

Inflammation-induced emergency megakaryopoiesis driven by hematopoietic stem cell-like megakaryocyte progenitors.

Haas S, Hansson J, Klimmeck D, Loeffler D, Velten L, Uckelmann H, Wurzer S, Prendergast ÁM, Schnell A, Hexel K, Santarella-Mellwig R, Blaszkiewicz S, Kuck A, Geiger H, Milsom MD, Steinmetz LM, Schroeder T, Trumpp A, Krijgsveld J, Essers MA

Cell stem cell, 2015

doi:10.1016/j.stem.2015.07.007.

In situ structural analysis of the human nuclear pore complex.

von Appen A, Kosinski J, Sparks L, Ori A, DiGuilio AL, Vollmer B, Mackmull MT, Banterle N, Parca L, Kastritis P, Buczak K, Mosalaganti S, Hagen W, Andres-Pons A, Lemke EA, Bork P, Antonin W, Glavy JS, Bui KH, Beck M

Nature, 2015

doi:10.1038/nature15381.

Distinct Trafficking of Cell Surface and Endosomal TIM-1 to the Immune Synapse.

Echbarthi M, Zonca M, Mellwig R, Schwab Y, Kaplan G, DeKruyff RH, Roda-Navarro P, Casasnovas JM

Traffic (Copenhagen, Denmark), 2015

doi:10.1111/tra.12329.

NS5A domain 1 and polyprotein cleavage kinetics are critical for induction of double-membrane vesicles associated with hepatitis C virus replication.

Romero-Brey I, Berger C, Kallis S, Kolovou A, Paul D, Lohmann V, Bartenschlager R

mBio, 2015

doi:10.1128/mBio.00759-15.

ENDOCYTOSIS. Endocytic sites mature by continuous bending and remodeling of the clathrin coat.

Avinoam O, Schorb M, Beese CJ, Briggs JA, Kaksonen M

Science (New York, N.Y.), 2015

doi:10.1126/science.aaa9555.

Structural analysis of the roles of influenza A virus membrane-associated proteins in assembly and morphology.

Chlanda P, Schraidt O, Kummer S, Riches J, Oberwinkler H, Prinz S, Kräusslich HG, Briggs JA

Journal of virology, 2015

doi:10.1128/JVI.00592-15.

Absolute Arrangement of Subunits in Cytoskeletal Septin Filaments in Cells Measured by Fluorescence Microscopy.

Kaplan C, Jing B, Winterflood CM, Bridges AA, Occhipinti P, Schmied J, Grinhagens S, Gronemeyer T, Tinnefeld P, Gladfelter AS, Ries J, Ewers H

Nano letters, 2015

doi:10.1021/acs.nanolett.5b00693.

Insulin granules. Insulin secretory granules control autophagy in pancreatic β cells.

Goginashvili A, Zhang Z, Erbs E, Spiegelhalter C, Kessler P, Mihlan M, Pasquier A, Krupina K, Schieber N, Cinque L, Morvan J, Sumara I, Schwab Y, Settembre C, Ricci R

Science (New York, N.Y.), 2015

doi:10.1126/science.aaa2628.

Visualizing the functional architecture of the endocytic machinery.

Picco A, Mund M, Ries J, Nédélec F, Kaksonen M

eLife, 2015

doi:10.7554/eLife.04535.

Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders.

Aiyar RS, Bohnert M, Duvezin-Caubet S, Voisset C, Gagneur J, Fritsch ES, Couplan E, von der Malsburg K, Funaya C, Soubigou F, Courtin F, Suresh S, Kucharczyk R, Evrard J, Antony C, St Onge RP, Blondel M, di Rago JP, van der Laan M, Steinmetz LM

Nature Communications, 2014

doi:10.1038/ncomms6585.

Correlating Intravital Multi-Photon Microscopy to 3D Electron Microscopy of Invading Tumor Cells Using Anatomical Reference Points.

Karreman MA, Mercier L, Schieber NL, Shibue T, Schwab Y, Goetz JG

PloS one, 2014

doi:10.1371/journal.pone.0114448.

Daclatasvir-like inhibitors of NS5A block early biogenesis of hepatitis C virus-induced membranous replication factories, independent of RNA replication.

Berger C, Romero-Brey I, Radujkovic D, Terreux R, Zayas M, Paul D, Harak C, Hoppe S, Gao M, Penin F, Lohmann V, Bartenschlager R

Gastroenterology, 2014

doi:10.1053/j.gastro.2014.07.019.

Automated Stitching of Microtubule Centerlines across Serial Electron Tomograms.

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