Boulard Group

Epigenetic gene silencing in mammals


Methylation-directed glycosylation of chromatin factors represses retrotransposon promoters.

Boulard M, Rucli S, Edwards JR, Bestor TH

Proceedings of the National Academy of Sciences of the United States of America 2020


BAH domains and a histone-like motif in DNA methyltransferase 1 (DNMT1) regulate de novo and maintenance methylation in vivo.

Yarychkivska O, Shahabuddin Z, Comfort N, Boulard M, Bestor TH

The Journal of biological chemistry 2018


DNA methylation and DNA methyltransferases.

Edwards JR, Yarychkivska O, Boulard M, Bestor TH

Epigenetics & chromatin 2017


Abnormal X chromosome inactivation and sex-specific gene dysregulation after ablation of FBXL10

Boulard M, Edwards JR, Bestor TH

Epigenetics & chromatin 2016


Notes on the role of dynamic DNA methylation in mammalian development

Bestor TH, Edwards JR, Boulard M

Proceedings of the National Academy of Sciences of the United States of America 2015


FBXL10 protects Polycomb-bound genes from hypermethylation

Boulard M, Edwards JR, Bestor TH

Nature genetics 2015


Histone variant macroH2A1 deletion in mice causes female-specific steatosis

Boulard M, Storck S, Cong R, Pinto R, Delage H, Bouvet P

Epigenetics & chromatin 2010


The incorporation of the novel histone variant H2AL2 confers unusual structural and functional properties of the nucleosome

Syed SH, Boulard M, Shukla MS, Gautier T, Travers A, Bednar J, Faivre-Moskalenko C, Dimitrov S, Angelov D

Nucleic acids research 2009


Germline mutation in RNASEL predicts increased risk of head and neck, uterine cervix and breast cancer

Madsen BE, Ramos EM, Boulard M, Duda K, Overgaard J, Nordsmark M, Wiuf C, Hansen LL

PloS one 2008


Histone variant nucleosomes: structure, function and implication in disease

Boulard M, Bouvet P, Kundu TK, Dimitrov S

Sub-cellular biochemistry 2007


The NH2 tail of the novel histone variant H2BFWT exhibits properties distinct from conventional H2B with respect to the assembly of mitotic chromosomes

Boulard M, Gautier T, Mbele GO, Gerson W, Hamiche A, Angelov D, Bouvet P, Dimitrov S

Molecular and cellular biology 2006


Control of the vascular endothelial growth factor internal ribosome entry site (IRES) activity and translation initiation by alternatively spliced coding sequences

Bornes S, Boulard M, Hieblot C, Zanibellato C, Iacovoni JS, Prats H, Touriol C

The Journal of biological chemistry 2004