The ageing genome: from mechanisms to disease – Course and Conference Office

EMBO | EMBL Symposium

The ageing genome: from mechanisms to disease


Registration is not yet open for this event. If you are interested in receiving more information please register your interest.

This conference will take place at EMBL Heidelberg, with the option to attend virtually.

Symposium overview

Ageing is often considered a complex phenotype that affects multiple organs and tissues in a time-dependent manner. This may result in the aged population consuming a myriad of medications, each aimed to treat, but not cure, the affected tissue.

Recent studies have demonstrated that the “Primary Hallmarks of Ageing” are a set of five molecular mechanisms that malfunction, independent of tissue type, and drive ageing. Hence, focusing on these five hallmarks simplifies the efforts to understand ageing-associated disease.

This, the second edition of this symposium will bring together an all-new, international line-up of speakers to continue the exchange on the basic/mechanistic aspects of chromosome biology with the applied and emerging field of ageing sciences. As more and more interventions and supplements flood the market, claiming to attenuate aging processes, it is critical that we investigate genomic changes during the ageing process. To keep the symposium fresh, in 2025 there will be new emphasis on the importance of chromatin changes and telomere dysfunction, nonetheless keeping in mind how they also affect DNA damage and repair responses

This symposium will bring together many diverse fields across topics including the below, and tie them together with the field of ageing biology and its relevant models of ageing.


  • DNA replication
  • DNA repair
  • telomere biology
  • chromatin regulation
  • nuclear architecture


Keynote Speakers

Eva Hoffman

University of Copenhagen


Joachim Lingner




Simon Boulton

The Francis Crick Institute


Daphne Cabianca

Helmholtz Munich


Ross Chapman

University of Oxford


Eiji Hara

Osaka University


Andrew Jackson

The University of Edinburgh


Gaëlle Legube

Paul Sabatier University


Rong Li

National University of Singapore


Scott Lowe

Memorial Sloan Kettering Cancer Center


Thi Hoang Duong (Kelly) Nguyen

MRC Laboratory of Molecular Biology


Serena Nik-Zainal

University of Cambridge


Patricia Opresko

University of Pittsburgh


Bjoern Schwer

University of California, San Francisco


John Sedivy

Brown University


Julian Stingele

Ludwig Maximilian University of Munich


Scientific organisers

George Garinis

Institute of Molecular Biology & Biotechnology



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EMBO | EMBL Symposia promote scientific communication and collaboration in the European research area. They provide scientists with a platform to discuss and exchange ideas on forward-looking topics and new developments in the life sciences.

Topics emphasise upcoming developments and the interdisciplinary nature of related fields. Jointly funded and organised by EMBO and EMBL – and complementary to their respective courses, workshops, and conference programmes – the symposia promote scientific communication and collaboration.

All symposia are held in the EMBL Advanced Training Centre (ATC) in Heidelberg, Germany, or virtually.

Media kit

Want to let others know you’re attending this event? Take a look at our shareable media and feel free to use them in your social media channels or presentations.

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Date: 10 - 13 Jun 2025

Location: EMBL Heidelberg and Virtual

Venue: EMBL Advanced Training Centre


  • George Garinis
    Institute of Molecular Biology & Biotechnology, Greece
    • Jacqueline Jacobs
      Netherlands Cancer Institute, The Netherlands

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