Titia de Lange
The Rockefeller University
USA
Overview
This conference will take place at EMBL Heidelberg, with the option to attend virtually.
Registration is not yet open for this event. If you are interested in receiving more information please register your interest.
Symposium overview
Our understanding of eukaryotic DNA replication has grown dramatically in the past few years, and many areas are poised for further breakthroughs. These include the structure and dynamics of the DNA replication machinery and how origin firing is controlled in space and time across different tissues, during aging and in disease. It is now clear that DNA replication is tightly integrated with chromatin dynamics, epigenome maintenance and chromosome organization, and as such the field is expanding its scope.
Accurate DNA replication is important for genomic stability, and several human diseases, most notably cancer, are driven by DNA replication stress. Due to the rapid advances in understanding replication fork structure and function we are now on the brink of a new understanding of replication fork stability, protection and repair. These forthcoming insights will advance our understanding of cancer etiology and lay the foundation for new therapies. By bringing together experts in the basic biology of DNA replication and genome maintenance, this EMBO | EMBL Symposium aims to fuel progress in these important fields.
Session topics
- Replisome structure and function
- Replication in time and space
- Chromatin replication and cell fate
- Replication stress and genome stability
- Replication-coupled DNA repair
- Replication in development, aging, and cancer
What past participants say about the conference
“I was impressed by the number of PIs who were present. Everyone working in our field in Europe showed up. The quality of work presented during talks and poster session was exceptional. There was plenty of time to talk to people which made for a terrific meeting.” — Agata Smogorzewska, The Rockefeller University, USA
“The conference has helped me to keep up to date with the latest development of the field and make new contacts with various researchers. These are valuable aspects for both my professional development and scientific research.” — Ronald Wong, Institute of Molecular Biology, Germany
Speakers
Keynote speakers
Thanos Halazonetis
University of Geneva
Switzerland
Speakers
Constance Alabert
University of Dundee
UK
Franziska Bleichert
Yale University
USA
Gheorghe Chistol
Stanford University
USA
David Cortez
Vanderbilt University
USA
Daniel Gerlich
Austrian Academy of Sciences
Austria
Vera Gorbunova
University of Rochester
USA
Stephan Hamperl
Helmholtz Munich
Germany
Ichiro Hiratani
RIKEN Center for Biosystems Dynamics Research
Japan
Masato Kanemaki
National Institute of Genetics
Japan
Puck Knipscheer
Hubrecht Institute
The Netherlands
Francesca Mattiroli
Hubrecht Institute
The Netherlands
Lori Passmore
MRC Laboratory of Molecular Biology
UK
Frank Uhlmann
The Francis Crick Institute
UK
Joseph Yeeles
MRC Laboratory of Molecular Biology
UK
Scientific organisers
Anja Groth
University of Copenhagen
Denmark
Helle Ulrich
Institute of Molecular Biology (IMB)
Germany
Johannes Walter
Harvard Medical School
USA
Conference organiser
Luana Ribeiro
EMBL Heidelberg
Germany
Sponsors
Media partners
Advanced Biology, a Wiley journal
Cancer Drug Resistance, an OAE Publishing Inc. journal
Genes and Development, a Cold Spring Harbor Journal
Genome Research, a Cold Spring Harbor Journal
Geromedicine, a Science Exploration Press journal
International Union of Biochemistry and Molecular Biology
Journal of Personalized Medicine, a MDPI journal
Medinformatics, a Bon View Publishing journal
Methods and Protocols, a MDPI journal
Open Biology, a Royal Society journal
Synthetic Biology and Engineering, a Sciepublish journal
The EMBO Journal, an EMBO Press journal
Sponsorship opportunities
We offer a variety of event sponsoring possibilities, with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget. Discounts are available for companies sponsoring multiple events at EMBL Heidelberg. View other conferences, or contact sponsorship@embl.de for further information.
If you are interested in becoming a media partner of this event, please visit our media partnerships webpage.
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About
EMBO | EMBL Symposia promote scientific communication and collaboration in the European research area. They provide scientists with a platform to discuss and exchange ideas on forward-looking topics and new developments in the life sciences.
Topics emphasise upcoming developments and the interdisciplinary nature of related fields. Jointly funded and organised by EMBO and EMBL – and complementary to their respective courses, workshops, and conference programmes – the symposia promote scientific communication and collaboration.
All symposia are held in the EMBL Advanced Training Centre (ATC) in Heidelberg, Germany, or virtually.
Date: 20 - 23 Oct 2026
Location: EMBL Heidelberg and Virtual
Venue: EMBL Advanced Training Centre
Organisers:
-
Anja Groth
University of Copenhagen, Denmark -
Helle Ulrich
Institute of Molecular Biology (IMB), Germany -
Johannes Walter
Harvard Medical School, USA
Contact: Luana Ribeiro