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Genome biology

Genome assemblies

Piecing together the best reference genome

Researchers reveal the best technology for assembling reference…

By Vicky Hatch

Science
Woman with long brown hair stands in front of snow scene with arms crossed in front of her.

Welcome: Sinem Saka

As one of EMBL’s newest group leaders, Sinem Saka will combine multiple technologies, such as microscopy and single-cell omics, to solve biological…

By Ivy Kupec

Lab Matters
Microscopy images of coronavirus-infected cells in blue and red, arranged on a clockface. Illustrations of virus particles.

Finding coronavirus’s helper proteins

A team of EMBL scientists and colleagues have analysed how the novel coronavirus affects proteins in human cells. They identified several human…

By Marius Bruer

Science
Illustration of a rod-shaped bacterial cell, superimposed on a red and blue background.

Heating proteins to understand how genes work

A new paper from EMBL’s Savitski team and Typas group describes their work on E. coli and how it brings a greater understanding of the way genes…

By Edward Prior

Science
An embryo of the fruit fly Drosophila.

Predicting how gene expression varies

Discoveries at EMBL will help researchers to interpret one of the most common types of experiments in genomics and medical…

By Fabian Oswald

Science
An illustration of single-cell RNA sequencing (scRNA-seq)

Enabling functional genomics studies in individual cells

Scientists at EMBL Heidelberg have developed a new method, called Targeted Perturb-seq (TAP-seq), which increases the scale and precision of…

By Marius Bruer

Science
Key visual for the EMBO | EMBL symposium ‘The Four-Dimensional Genome’

EMBL hosts its first virtual conference

The virtual EMBO | EMBL symposium ‘The Four-Dimensional Genome’ brought together 470 participants. Here, Jürgen Deka, Head of External…

By Marius Bruer

Events

New insights into gene regulation

EMBL researchers investigate the role of a histone protein in regulating gene…

By Chloe Cross

Science
A visualisation of a membraneless organelle in the green-yellow style of the data presented in the Nature Communications paper

ATP affects proteome-wide solubility

Scientists develop technology to measure how ATP concentration affects protein solubility in…

By Josh Tapley

Science
As a cell prepares to divide, the chromosomes (shown here in pink) condense, becoming more tightly coiled and easier to observe under the microscope. The faint structure in the centre is a cell nucleus in which the chromosomes are in their usual decondensed state.

Exploring genetic variation

EMBL group leader Jan Korbel reflects on his scientific origins and current…

By Edward Dadswell

Science
How drugs affect the life and death of proteins. IMAGE: Cell

How drugs affect the life and death of proteins

Scientists at EMBL and Cellzome develop technology to monitor the effects of drug treatments on protein degradation and…

By Iris Kruijen

Science
Architecture dependent turnover of the nuclear pore subunits. Top row shows the nuclear pore subunits seen from top, bottom row shows subunits of the nuclear pore cut in half.

Life and death of proteins

EMBL scientists create a turnover catalogue of almost 10.000 proteins from primary…

By Berta Carreño

Science

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