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cryo-ET

Female scientist stands in front of electron microscope that is taller than she is

Seeing deeper inside cells

While cryo-electron tomography (cryo-ET) was first envisioned in 1968, the advances the Mahamid group are bringing to this 3D method for studying…

By Ivy Kupec

Science

This visual representation shows the newly identified architecture (left) of the coupled molecular machines responsible for transcription (green; DNA in magenta) and translation (blue and yellow), accompanied by the protein interaction network from mass spectrometry (centre) and the cryo-electron tomography data (right) from Mycoplasma pneumoniae that was used to model the structure. Credit: Liang Xue and Julia Mahamid/EMBL

Visualising the cell’s molecular machinery in action

A new approach that allows researchers to see molecular machinery at work inside cells has offered a deeper understanding of how bacteria produce…

By Ivy Kupec

Science

The retromer complex

Solving the structure of retromer

Retromer’s 3D structure improves understanding of cellular sorting and…

By Guest author(s)

Science

The closest look ever at native human tissue

Seeing proteins in their natural environment and interactions inside cells has been a longstanding goal. Using an advanced microscopy technique…

By Guest author(s)

Science

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