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CRISPR Archives | EMBL

An illustration of single-cell RNA sequencing (scRNA-seq)

Enabling functional genomics studies in individual cells

Scientists at EMBL Heidelberg have developed a new method, called Targeted Perturb-seq (TAP-seq), which increases the scale and precision of functional genomics CRISPR–Cas9 screens by orders of magnitude. Their method overcomes limitations in previous applications of single-cell RNA sequencing, and will enable scientists to perform functional genomics experiments on an unprecedented scale.

By Marius Bruer

Science

Cell division

Tracing the origins of cells

Researchers from the Sharpe group at EMBL Barcelona have published a method to track the developmental history of a cell using the gene editing tool CRISPR–Cas9, but without the need to create transgenic organisms.

By Fabian Oswald

Science

A model of CRISPR/Cas9

Wielding the genetic scissors

What CRISPR may bring for the future of biology, and how it is used at EMBL

By Fabian Oswald

Science

Prioritising cancer drug targets using CRISPR

Large CRISPR screen prioritises hundreds of promising genes for personalised cancer treatment

By Oana Stroe

Science

Members of GeneCore Jonathan Landry, Vladimir Benes and Anja Telzerow.

DIY Biology kits: what’s really growing inside?

EMBL’s GeneCore steps up to discover the facts and settle disputes

By Emma Steer

Lab Matters

Artist's representation of double helix next to black mouse.

Deleting genes to study how germ cells are born

How embryonic stem cells develop into the germ line

By Patrick Mueller

Science

New Platform Transforms CRISPR Gene Editor Into Precision Tool. IMAGE: Irvine/NIST

CRISPR: from clipping scissors to word processor

New platform transforms CRISPR gene editor into precision tool

By Iris Kruijen

Science

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