CRISPR Archives | EMBL
Enabling functional genomics studies in individual cells
Scientists at EMBL Heidelberg have developed a new method, called Targeted Perturb-seq (TAP-seq), which increases the scale and precision of functional genomics CRISPR–Cas9 screens by orders of magnitude. Their method overcomes limitations in previous applications of single-cell RNA sequencing, and will enable scientists to perform functional genomics experiments on an unprecedented scale.
Tracing the origins of cells
Researchers from the Sharpe group at EMBL Barcelona have published a method to track the developmental history of a cell using the gene editing tool CRISPR–Cas9, but without the need to create transgenic organisms.
Wielding the genetic scissors
What CRISPR may bring for the future of biology, and how it is used at EMBL
Prioritising cancer drug targets using CRISPR
Large CRISPR screen prioritises hundreds of promising genes for personalised cancer treatment
DIY Biology kits: what’s really growing inside?
EMBL’s GeneCore steps up to discover the facts and settle disputes
Deleting genes to study how germ cells are born
How embryonic stem cells develop into the germ line
CRISPR: from clipping scissors to word processor
New platform transforms CRISPR gene editor into precision tool
