CLEMSite, a software for automated phenotypic screens using light microscopy and FIB-SEM.

Serra Lleti JM, Steyer AM, Schieber NL, Neumann B, Tischer C, Hilsenstein V, Holtstrom M, Unrau D, Kirmse R, Lucocq JM, Pepperkok R, Schwab Y

The Journal of cell biology, 2022

doi:10.1083/jcb.202209127.

The importance of nuclear RAGE-Mcm2 axis in diabetes or cancer-associated replication stress.

Han Z, Andrš M, Madhavan BK, Kaymak S, Sulaj A, Kender Z, Kopf S, Kihm L, Pepperkok R, Janscak P, Nawroth P, Kumar V

Nucleic acids research, 2023

doi:10.1093/nar/gkad085.

Repression of the iron exporter ferroportin may contribute to hepatocyte iron overload in individuals with type 2 diabetes.

Qiu R, Alikhanyan K, Volk N, Marques O, Mertens C, Agarvas AR, Singh S, Pepperkok R, Altamura S, Muckenthaler MU

Molecular metabolism, 2022

doi:10.1016/j.molmet.2022.101644.

Regulation of the COPII secretory machinery via focal adhesions and extracellular matrix signaling.

Jung J, Khan MM, Landry J, Halavatyi A, Machado P, Reiss M, Pepperkok R

The Journal of cell biology, 2022

doi:10.1083/jcb.202110081.

Priorities for ocean microbiome research.

Tara Ocean Foundation, Tara Oceans, European Molecular Biology Laboratory (EMBL), European Marine Biological Resource Centre - European Research Infrastructure Consortium (EMBRC-ERIC)

Nature microbiology, 2022

doi:10.1038/s41564-022-01145-5.

Functional profiling of LDLR variants: important evidence for variant classification: functional profiling of LDLR variants.

Graça R, Alves AC, Zimon M, Pepperkok R, Bourbon M

Journal of clinical lipidology, 2022

doi:10.1016/j.jacl.2022.04.005.

Systems Approaches to Unravel Molecular Function: High-content siRNA Screen Identifies TMEM16A Traffic Regulators as Potential Drug Targets for Cystic Fibrosis.

Pinto MC, Botelho HM, Silva IAL, Railean V, Neumann B, Pepperkok R, Schreiber R, Kunzelmann K, Amaral MD

Journal of molecular biology, 2022

doi:10.1016/j.jmb.2021.167436.

Pairwise effects between lipid GWAS genes modulate lipid plasma levels and cellular uptake.

Zimoń M, Huang Y, Trasta A, Halavatyi A, Liu JZ, Chen CY, Blattmann P, Klaus B, Whelan CD, Sexton D, John S, Huber W, Tsai EA, Pepperkok R, Runz H

Nature communications, 2021

doi:10.1038/s41467-021-26761-3.

A laser-mediated photo-manipulative toolbox for generation and real-time monitoring of DNA lesions.

Madhavan BK, Han Z, Sickmann A, Pepperkok R, Nawroth PP, Kumar V

STAR protocols, 2021

doi:10.1016/j.xpro.2021.100700.

Global distribution patterns of marine nitrogen-fixers by imaging and molecular methods.

Pierella Karlusich JJ, Pelletier E, Lombard F, Carsique M, Dvorak E, Colin S, Picheral M, Cornejo-Castillo FM, Acinas SG, Pepperkok R, Karsenti E, de Vargas C, Wincker P, Bowler C, Foster RA

Nature communications, 2021

doi:10.1038/s41467-021-24299-y.

Glucocorticoids exacerbate TGFß1 mediated fibrotic signalling in lung fibroblasts by inhibition of metalloproteinase expression and activity.

Khan MM, Zukowska-Kasprzyk J, Neumann B, Halavatyi A, Tischer C, Haberkant P, Stein F, Jung F, Landry J, Lewis J, Pepperkok R

ERJ open research, 2021

doi:10.1183/23120541.lsc-2021.33.

BigDataProcessor2: a free and open-source Fiji plugin for inspection and processing of TB sized image data.

Tischer C, Ravindran A, Reither S, Chiaruttini N, Pepperkok R, Norlin N

Bioinformatics (Oxford, England), 2021

doi:10.1093/bioinformatics/btab106.

A high throughput SEC23 functional interaction screen reveals a role for focal adhesion and extracellular matrix signalling in the regulation of COPII subunit SEC23A

Jung J, Khan MM, Landry J, Halavatyi A, Machado P, Reiss M, Pepperkok R

2021

doi:10.1101/2021.03.16.435679.

An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in ex vivo human precision-cut lung slices.

Khan MM, Poeckel D, Halavatyi A, Zukowska-Kasprzyk J, Stein F, Vappiani J, Sevin DC, Tischer C, Zinn N, Eley JD, Gudmann NS, Muley T, Winter H, Fisher AJ, Nanthakumar CB, Bergamini G, Pepperkok R

The European respiratory journal, 2020

doi:10.1183/13993003.00221-2020.

Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.

Matos AM, Pinto FR, Barros P, Amaral MD, Pepperkok R, Matos P

The Journal of biological chemistry, 2019

doi:10.1074/jbc.RA119.008738.

One step ahead: Innovation in core facilities.

Lippens S, D'Enfert C, Farkas L, Kehres A, Korn B, Morales M, Pepperkok R, Premvardhan L, Schlapbach R, Tiran A, Meder D, Van Minnebruggen G

EMBO reports, 2019

doi:10.15252/embr.201948017.

GM130 and p115 play a key role in the organisation of the early secretory pathway during skeletal muscle differentiation.

Giacomello E, Ronchi P, Pepperkok R

Journal of cell science, 2019

doi:10.1242/jcs.222083.

A novel microscopy-based assay identifies extended synaptotagmin-1 (ESYT1) as a positive regulator of anoctamin 1 traffic.

Lérias JR, Pinto MC, Botelho HM, Awatade NT, Quaresma MC, Silva IAL, Wanitchakool P, Schreiber R, Pepperkok R, Kunzelmann K, Amaral MD

Biochimica et biophysica acta, 2017

doi:10.1016/j.bbamcr.2017.11.009.

Quantitative 3D-imaging for cell biology and ecology of environmental microbial eukaryotes.

Colin S, Coelho LP, Sunagawa S, Bowler C, Karsenti E, Bork P, Pepperkok R, de Vargas C

eLife, 2017

doi:10.7554/eLife.26066.

Homeostatic nuclear RAGE-ATM interaction is essential for efficient DNA repair.

Kumar V, Fleming T, Terjung S, Gorzelanny C, Gebhardt C, Agrawal R, Mall MA, Ranzinger J, Zeier M, Madhusudhan T, Ranjan S, Isermann B, Liesz A, Deshpande D, Häring HU, Biswas SK, Reynolds PR, Hammes HP, Peperkok R, Angel P, Herzig S, Nawroth PP

Nucleic acids research, 2017

doi:10.1093/nar/gkx705.

Targeted Ablation Using Laser Nanosurgery.

Gayathri Vegesna NV, Ronchi P, Durdu S, Terjung S, Pepperkok R

Methods in molecular biology (Clifton, N.J.), 2017

doi:10.1007/978-1-4939-6810-7_8.

Profiling DNA damage response following mitotic perturbations.

S Pedersen R, Karemore G, Gudjonsson T, Rask MB, Neumann B, Hériché JK, Pepperkok R, Ellenberg J, Gerlich DW, Lukas J, Lukas C

Nature communications, 2016

doi:10.1038/ncomms13887.

Let there be light-at the right place.

Hufnagel L, Pepperkok R

Nature biotechnology, 2016

doi:10.1038/nbt.3738.

The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR.

Scharaw S, Iskar M, Ori A, Boncompain G, Laketa V, Poser I, Lundberg E, Perez F, Beck M, Bork P, Pepperkok R

The Journal of cell biology, 2016

doi:10.1083/jcb.201601090.

Institutional core facilities: prerequisite for breakthroughs in the life sciences: Core facilities play an increasingly important role in biomedical research by providing scientists access to sophisticated technology and expertise.

Meder D, Morales M, Pepperkok R, Schlapbach R, Tiran A, Van Minnebruggen G

EMBO reports, 2016

doi:10.15252/embr.201642857.

A microtubule-independent role of p150glued in secretory cargo concentration at endoplasmic reticulum exit sites.

Verissimo F, Halavatyi A, Pepperkok R, Weiss M

Journal of cell science, 2015

doi:10.1242/jcs.172395.

Erratum: Novel microscopy-based screening method reveals regulators of contact-dependent intercellular transfer.

Frei DM, Hodneland E, Rios-Mondragon I, Burtey A, Neumann B, Bulkescher J, Schölermann J, Pepperkok R, Gerdes HH, Kögel T

Scientific reports, 2015

doi:10.1038/srep14158.

Novel microscopy-based screening method reveals regulators of contact-dependent intercellular transfer.

Frei DM, Hodneland E, Rios-Mondragon I, Burtey A, Neumann B, Bulkescher J, Schölermann J, Pepperkok R, Gerdes HH, Kögel T

Scientific reports, 2015

doi:10.1038/srep12879.

Self-organization of core Golgi material is independent of COPII-mediated endoplasmic reticulum export

Schuberth CE, Tangemo C, Coneva C, Tischer C, Pepperkok R

JOURNAL OF CELL SCIENCE, 2015

doi:10.1242/jcs.154443.

High-throughput fluorescence correlation spectroscopy enables analysis of proteome dynamics in living cells.

Wachsmuth M, Conrad C, Bulkescher J, Koch B, Mahen R, Isokane M, Pepperkok R, Ellenberg J

Nature biotechnology, 2015

doi:10.1038/nbt.3146.

A fluorescent live imaging screening assay based on translocation criteria identifies novel cytoplasmic proteins implicated in GPCR signalling pathways.

Lecat S, Matthes HW, Pepperkok R, Simpson JC, Galzi JL

Molecular & cellular proteomics : MCP, 2015

doi:10.1074/mcp.m114.046698.

Protein traffic disorders: an effective high-throughput fluorescence microscopy pipeline for drug discovery.

Botelho HM, Uliyakina I, Awatade NT, Proença MC, Tischer C, Sirianant L, Kunzelmann K, Pepperkok R, Amaral MD

Scientific reports, 2015

doi:10.1038/srep09038.

Systematic Cell-Based Phenotyping of Missense Alleles Empowers Rare Variant Association Studies: A Case for LDLR and Myocardial Infarction.

Thormaehlen AS, Schuberth C, Won HH, Blattmann P, Joggerst-Thomalla B, Theiss S, Asselta R, Duga S, Merlini PA, Ardissino D, Lander ES, Gabriel S, Rader DJ, Peloso GM, Pepperkok R, Kathiresan S, Runz H

PLoS genetics, 2015

doi:10.1371/journal.pgen.1004855.

A direct role for ATP1A1 in unconventional secretion of fibroblast growth factor 2.

Zacherl S, La Venuta G, Müller HM, Wegehingel S, Dimou E, Sehr P, Lewis JD, Erfle H, Pepperkok R, Nickel W

The Journal of biological chemistry, 2015

doi:10.1074/jbc.m114.590067.

Positive feedback between golgi membranes, microtubules and ER-exit sites directs golgi de novo biogenesis.

Ronchi P, Tischer C, Acehan D, Pepperkok R

Journal of cell science, 2014

doi:10.1242/jcs.150474.

Adaptive fluorescence microscopy by online feedback image analysis.

Tischer C, Hilsenstein V, Hanson K, Pepperkok R

Methods in cell biology, 2014

doi:10.1016/b978-0-12-420138-5.00026-4.

An RNAi screen identifies KIF15 as a novel regulator of the endocytic trafficking of integrin.

Eskova A, Knapp B, Matelska D, Reusing S, Arjonen A, Lisauskas T, Pepperkok R, Russell R, Eils R, Ivaska J, Kaderali L, Erfle H, Starkuviene V

Journal of cell science, 2014

doi:10.1242/jcs.137281.

CNIH4 interacts with newly synthesized GPCR and controls their export from the endoplasmic reticulum.

Sauvageau E, Rochdi MD, Oueslati M, Hamdan FF, Percherancier Y, Simpson JC, Pepperkok R, Bouvier M

Traffic (Copenhagen, Denmark), 2014

doi:10.1111/tra.12148.

Plasma membrane translocation of REDD1 governed by GPCRs contributes to mTORC1 activation

Michel G, Matthes HW, Hachet-Haas M, El Baghdadi K, de Mey J, Pepperkok R, Simpson JC, Galzi JL, Lecat S

Journal of cell science, 2013

doi:10.1242/jcs.136432.

PIP₃ induces the recycling of receptor tyrosine kinases

Laketa V, Zarbakhsh S, Traynor-Kaplan A, Macnamara A, Subramanian D, Putyrski M, Mueller R, Nadler A, Mentel M, Saez-Rodriguez J, Pepperkok R, Schultz C

Science signaling, 2014

doi:10.1126/scisignal.2004532.

Imaging ER-to-Golgi transport: towards a systems view

Verissimo F, Pepperkok R

Journal of cell science, 2013

doi:10.1242/jcs.121061.

HIGH THROUGHPUT SCREEN REVEALS GENES REGULATING WT-CFTR AND RESCUING F508DEL-CFTR TRAFFIC

Botelho HM, Dahimene S, Uliyakina I, Neumann B, Tischer C, Pepperkok R, Amaral MD

PEDIATRIC PULMONOLOGY, 2013

doi:.

PtdIns(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complex

He S, Ni D, Ma B, Lee JH, Zhang T, Ghozalli I, Pirooz SD, Zhao Z, Bharatham N, Li B, Oh S, Lee WH, Takahashi Y, Wang HG, Minassian A, Feng P, Deretic V, Pepperkok R, Tagaya M, Yoon HS, Liang C

Nature cell biology, 2013

doi:10.1038/ncb2848.

High-content siRNA screen reveals global ENaC regulators and potential cystic fibrosis therapy targets

Almaça J, Faria D, Sousa M, Uliyakina I, Conrad C, Sirianant L, Clarke LA, Martins JP, Santos M, Heriché JK, Huber W, Schreiber R, Pepperkok R, Kunzelmann K, Amaral MD

Cell, 2013

doi:10.1016/j.cell.2013.08.045.

Cell-to-cell communication: current views and future perspectives

Gerdes HH, Pepperkok R

Cell and tissue research, 2013

doi:10.1007/s00441-013-1590-1.

Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells

Stadler C, Rexhepaj E, Singan VR, Murphy RF, Pepperkok R, Uhlén M, Simpson JC, Lundberg E

Nature methods, 2013

doi:10.1038/nmeth.2377.

RNAi-based functional profiling of loci from blood lipid genome-wide association studies identifies genes with cholesterol-regulatory function

Blattmann P, Schuberth C, Pepperkok R, Runz H

PLoS genetics, 2013

doi:10.1371/journal.pgen.1003338.

Characterization of drug-induced transcriptional modules: towards drug repositioning and functional understanding.

Iskar M, Zeller G, Blattmann P, Campillos M, Kuhn M, Kaminska KH, Runz H, Gavin AC, Pepperkok R, van Noort V, Bork P

Molecular systems biology, 2013

doi:10.1038/msb.2013.20.

Golgi depletion from living cells with laser nanosurgery

Ronchi P, Pepperkok R

Methods in cell biology, 2013

doi:10.1016/b978-0-12-417164-0.00019-7.

Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway

Simpson JC, Joggerst B, Laketa V, Verissimo F, Cetin C, Erfle H, Bexiga MG, Singan VR, Hériché JK, Neumann B, Mateos A, Blake J, Bechtel S, Benes V, Wiemann S, Ellenberg J, Pepperkok R

Nature cell biology, 2012

doi:10.1038/ncb2510.

Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1.

Moudry P, Lukas C, Macurek L, Neumann B, Heriche JK, Pepperkok R, Ellenberg J, Hodny Z, Lukas J, Bartek J

Cell death and differentiation, 2012

doi:10.1038/cdd.2011.150.

At the cutting edge: applications and perspectives of laser nanosurgery in cell biology

Ronchi P, Terjung S, Pepperkok R

Biological chemistry, 2012

doi:10.1515/hsz-2011-0237.

Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy

Stadler C, Hjelmare M, Neumann B, Jonasson K, Pepperkok R, Uhlén M, Lundberg E

Journal of proteomics, 2012

doi:10.1016/j.jprot.2012.01.030.

A new approach to manipulate the fate of single neural stem cells in tissue

Taverna E, Haffner C, Pepperkok R, Huttner WB

Nature neuroscience, 2012

doi:10.1038/nn.3008.

Molecular recognition of a single sphingolipid species by a protein's transmembrane domain

Contreras FX, Ernst AM, Haberkant P, Björkholm P, Lindahl E, Gönen B, Tischer C, Elofsson A, von Heijne G, Thiele C, Pepperkok R, Wieland F, Brügger B

Nature, 2012

doi:10.1038/nature10742.

Chemical chaperones improve protein secretion and rescue mutant factor VIII in mice with hemophilia A

Roth SD, Schüttrumpf J, Milanov P, Abriss D, Ungerer C, Quade-Lyssy P, Simpson JC, Pepperkok R, Seifried E, Tonn T

PloS one, 2012

doi:10.1371/journal.pone.0044505.

Quantifying the influence of yellow fluorescent protein photoconversion on acceptor photobleaching-based fluorescence resonance energy transfer measurements.

Seitz A, Terjung S, Zimmermann T, Pepperkok R

Journal of biomedical optics, 2012

doi:10.1117/1.jbo.17.1.011010.

Phenotypic profiling of the human genome reveals gene products involved in plasma membrane targeting of SRC kinases

Ritzerfeld J, Remmele S, Wang T, Temmerman K, Brügger B, Wegehingel S, Tournaviti S, Strating JR, Wieland FT, Neumann B, Ellenberg J, Lawerenz C, Hesser J, Erfle H, Pepperkok R, Nickel W

Genome research, 2011

doi:10.1101/gr.116087.110.

Quantitative proteomics and dynamic imaging of the nucleolus reveal distinct responses to UV and ionizing radiation

Moore HM, Bai B, Boisvert FM, Latonen L, Rantanen V, Simpson JC, Pepperkok R, Lamond AI, Laiho M

Molecular & cellular proteomics : MCP, 2011

doi:10.1074/mcp.m111.009241.

Micropilot: automation of fluorescence microscopy-based imaging for systems biology

Conrad C, Wünsche A, Tan TH, Bulkescher J, Sieckmann F, Verissimo F, Edelstein A, Walter T, Liebel U, Pepperkok R, Ellenberg J

Nature methods, 2011

doi:10.1038/nmeth.1558.

A novel laser nanosurgery approach supports de novo Golgi biogenesis in mammalian cells

Tängemo C, Ronchi P, Colombelli J, Haselmann U, Simpson JC, Antony C, Stelzer EH, Pepperkok R, Reynaud EG

Journal of cell science, 2011

doi:10.1242/jcs.079640.

Functional genomics assays to study CFTR traffic and ENaC function

Almaça J, Dahimène S, Appel N, Conrad C, Kunzelmann K, Pepperkok R, Amaral MD

Methods in molecular biology (Clifton, N.J.), 2011

doi:10.1007/978-1-61779-120-8_15.

Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment.

Reiss S, Rebhan I, Backes P, Romero-Brey I, Erfle H, Matula P, Kaderali L, Poenisch M, Blankenburg H, Hiet MS, Longerich T, Diehl S, Ramirez F, Balla T, Rohr K, Kaul A, Bühler S, Pepperkok R, Lengauer T, Albrecht M, Eils R, Schirmacher P, Lohmann V, Bartenschlager R

Cell host & microbe, 2011

doi:10.1016/j.chom.2010.12.002.

High-throughput microscopy using live mammalian cells.

Terjung S, Walter T, Seitz A, Neumann B, Pepperkok R, Ellenberg J

Cold Spring Harbor protocols, 2010

doi:10.1101/pdb.top84.

Tec-kinase-mediated phosphorylation of fibroblast growth factor 2 is essential for unconventional secretion

Ebert AD, Laussmann M, Wegehingel S, Kaderali L, Erfle H, Reichert J, Lechner J, Beer HD, Pepperkok R, Nickel W

Traffic (Copenhagen, Denmark), 2010

doi:10.1111/j.1600-0854.2010.01059.x.

In situ analysis of tyrosine phosphorylation networks by FLIM on cell arrays

Grecco HE, Roda-Navarro P, Girod A, Hou J, Frahm T, Truxius DC, Pepperkok R, Squire A, Bastiaens PI

Nature methods, 2010

doi:10.1038/nmeth.1458.

Activation of membrane-permeant caged PtdIns(3)P induces endosomal fusion in cells

Subramanian D, Laketa V, Müller R, Tischer C, Zarbakhsh S, Pepperkok R, Schultz C

Nature chemical biology, 2010

doi:10.1038/nchembio.348.

Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes

Neumann B, Walter T, Hériché JK, Bulkescher J, Erfle H, Conrad C, Rogers P, Poser I, Held M, Liebel U, Cetin C, Sieckmann F, Pau G, Kabbe R, Wünsche A, Satagopam V, Schmitz MH, Chapuis C, Gerlich DW, Schneider R, Eils R, Huber W, Peters JM, Hyman AA, Durbin R, Pepperkok R, Ellenberg J

Nature, 2010

doi:10.1038/nature08869.

Automatic identification and clustering of chromosome phenotypes in a genome wide RNAi screen by time-lapse imaging

Walter T, Held M, Neumann B, Hériché JK, Conrad C, Pepperkok R, Ellenberg J

Journal of structural biology, 2010

doi:10.1016/j.jsb.2009.10.004.

From experimental setup to bioinformatics: an RNAi screening platform to identify host factors involved in HIV-1 replication

Börner K, Hermle J, Sommer C, Brown NP, Knapp B, Glass B, Kunkel J, Torralba G, Reymann J, Beil N, Beneke J, Pepperkok R, Schneider R, Ludwig T, Hausmann M, Hamprecht F, Erfle H, Kaderali L, Kräusslich HG, Lehmann MJ

Biotechnology journal, 2010

doi:10.1002/biot.200900226.

Factor VIII-eGFP fusion proteins with preserved functional activity for the analysis of the early secretory pathway of factor VIII

Heinz S, Schüttrumpf J, Simpson JC, Pepperkok R, Nicolaes GA, Abriss D, Milanov P, Roth S, Seifried E, Tonn T

Thrombosis and haemostasis, 2009

doi:10.1160/th08-12-0807.

Membrane-permeant phosphoinositide derivatives as modulators of growth factor signaling and neurite outgrowth

Laketa V, Zarbakhsh S, Morbier E, Subramanian D, Dinkel C, Brumbaugh J, Zimmermann P, Pepperkok R, Schultz C

Chemistry & biology, 2009

doi:10.1016/j.chembiol.2009.10.005.

DetecTiff: a novel image analysis routine for high-content screening microscopy

Gilbert DF, Meinhof T, Pepperkok R, Runz H

Journal of biomolecular screening, 2009

doi:10.1177/1087057109339523.

Mutations affecting the secretory COPII coat component SEC23B cause congenital dyserythropoietic anemia type II

Schwarz K, Iolascon A, Verissimo F, Trede NS, Horsley W, Chen W, Paw BH, Hopfner KP, Holzmann K, Russo R, Esposito MR, Spano D, De Falco L, Heinrich K, Joggerst B, Rojewski MT, Perrotta S, Denecke J, Pannicke U, Delaunay J, Pepperkok R, Heimpel H

Nature genetics, 2009

doi:10.1038/ng.405.

Reversible phosphorylation as a molecular switch to regulate plasma membrane targeting of acylated SH4 domain proteins

Tournaviti S, Pietro ES, Terjung S, Schafmeier T, Wegehingel S, Ritzerfeld J, Schulz J, Smith DF, Pepperkok R, Nickel W

Traffic (Copenhagen, Denmark), 2009

doi:10.1111/j.1600-0854.2009.00921.x.

Identification of cholesterol-regulating genes by targeted RNAi screening

Bartz F, Kern L, Erz D, Zhu M, Gilbert D, Meinhof T, Wirkner U, Erfle H, Muckenthaler M, Pepperkok R, Runz H

Cell metabolism, 2009

doi:10.1016/j.cmet.2009.05.009.

ojoplano-mediated basal constriction is essential for optic cup morphogenesis

Martinez-Morales JR, Rembold M, Greger K, Simpson JC, Brown KE, Quiring R, Pepperkok R, Martin-Bermudo MD, Himmelbauer H, Wittbrodt J

Development (Cambridge, England), 2009

doi:10.1242/dev.033563.

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

Doil C, Mailand N, Bekker-Jensen S, Menard P, Larsen DH, Pepperkok R, Ellenberg J, Panier S, Durocher D, Bartek J, Lukas J, Lukas C

Cell, 2009

doi:10.1016/j.cell.2008.12.041.

Rab18 and Rab43 have key roles in ER-Golgi trafficking

Dejgaard SY, Murshid A, Erman A, Kizilay O, Verbich D, Lodge R, Dejgaard K, Ly-Hartig TB, Pepperkok R, Simpson JC, Presley JF

Journal of cell science, 2008

doi:10.1242/jcs.021808.

Work flow for multiplexing siRNA assays by solid-phase reverse transfection in multiwell plates

Erfle H, Neumann B, Rogers P, Bulkescher J, Ellenberg J, Pepperkok R

Journal of biomolecular screening, 2008

doi:10.1177/1087057108320133.

In migrating cells, the Golgi complex and the position of the centrosome depend on geometrical constraints of the substratum

Pouthas F, Girard P, Lecaudey V, Ly TB, Gilmour D, Boulin C, Pepperkok R, Reynaud EG

Journal of cell science, 2008

doi:10.1242/jcs.026849.

Human Proteinpedia enables sharing of human protein data

Mathivanan S, Ahmed M, Ahn NG, Alexandre H, Amanchy R, Andrews PC, Bader JS, Balgley BM, Bantscheff M, Bennett KL, Björling E, Blagoev B, Bose R, Brahmachari SK, Burlingame AS, Bustelo XR, Cagney G, Cantin GT, Cardasis HL, Celis JE, Chaerkady R, Chu F, Cole PA, Costello CE, Cotter RJ, Crockett D, DeLany JP, De Marzo AM, DeSouza LV, Deutsch EW, Dransfield E, Drewes G, Droit A, Dunn MJ, Elenitoba-Johnson K, Ewing RM, Van Eyk J, Faca V, Falkner J, Fang X, Fenselau C, Figeys D, Gagné P, Gelfi C, Gevaert K, Gimble JM, Gnad F, Goel R, Gromov P, Hanash SM, Hancock WS, Harsha HC, Hart G, Hays F, He F, Hebbar P, Helsens K, Hermeking H, Hide W, Hjernø K, Hochstrasser DF, Hofmann O, Horn DM, Hruban RH, Ibarrola N, James P, Jensen ON, Jensen PH, Jung P, Kandasamy K, Kheterpal I, Kikuno RF, Korf U, Körner R, Kuster B, Kwon MS, Lee HJ, Lee YJ, Lefevre M, Lehvaslaiho M, Lescuyer P, Levander F, Lim MS, Löbke C, Loo JA, Mann M, Martens L, Martinez-Heredia J, McComb M, McRedmond J, Mehrle A, Menon R, Miller CA, Mischak H, Mohan SS, Mohmood R, Molina H, Moran MF, Morgan JD, Moritz R, Morzel M, Muddiman DC, Nalli A, Navarro JD, Neubert TA, Ohara O, Oliva R, Omenn GS, Oyama M, Paik YK, Pennington K, Pepperkok R, Periaswamy B, Petricoin EF, Poirier GG, Prasad TS, Purvine SO, Rahiman BA, Ramachandran P, Ramachandra YL, Rice RH, Rick J, Ronnholm RH, Salonen J, Sanchez JC, Sayd T, Seshi B, Shankari K, Sheng SJ, Shetty V, Shivakumar K, Simpson RJ, Sirdeshmukh R, Siu KW, Smith JC, Smith RD, States DJ, Sugano S, Sullivan M, Superti-Furga G, Takatalo M, Thongboonkerd V, Trinidad JC, Uhlen M, Vandekerckhove J, Vasilescu J, Veenstra TD, Vidal-Taboada JM, Vihinen M, Wait R, Wang X, Wiemann S, Wu B, Xu T, Yates JR, Zhong J, Zhou M, Zhu Y, Zurbig P, Pandey A

Nature biotechnology, 2008

doi:10.1038/nbt0208-164.

ER-to-Golgi transport

Verissimo F, Pepperkok R

2008

doi:10.1007/978-3-211-76310-0_20.

A correlative light and electron microscopy method based on laser micropatterning and etching

Colombelli J, Tängemo C, Haselman U, Antony C, Stelzer EH, Pepperkok R, Reynaud EG

Methods in molecular biology (Clifton, N.J.), 2008

doi:10.1007/978-1-59745-261-8_15.

Integrating systems biology with clinical research

Pepperkok R, Wiemann S

Genome biology, 2008

doi:10.1186/gb-2008-9-7-314.

A genome wide RNAI screen by time lapse microscopy in order to identify mitotic genes - Computational aspects and challenges.

Walter T, Held M, Neumann B, Heriche JK, Conrad C, Pepperkok R, Ellenberg J

2008 IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING: FROM NANO TO MACRO, VOLS 1-4, 2008

doi:10.1109/ISBI.2008.4540999.

The potential of high-content high-throughput microscopy in drug discovery

Starkuviene V, Pepperkok R

British journal of pharmacology, 2007

doi:10.1038/sj.bjp.0707346.

Differential requirements for ts-O45-G and procollagen biosynthetic transport

Starkuviene V, Pepperkok R

Traffic (Copenhagen, Denmark), 2007

doi:10.1111/j.1600-0854.2007.00582.x.

Transfected cell microarrays: an efficient tool for high-throughput functional analysis

Starkuviene V, Pepperkok R, Erfle H

Expert review of proteomics, 2007

doi:10.1586/14789450.4.4.479.

An RNAi screening platform to identify secretion machinery in mammalian cells

Simpson JC, Cetin C, Erfle H, Joggerst B, Liebel U, Ellenberg J, Pepperkok R

Journal of biotechnology, 2007

doi:10.1016/j.jbiotec.2006.12.027.

Reverse transfection on cell arrays for high content screening microscopy.

Erfle H, Neumann B, Liebel U, Rogers P, Held M, Walter T, Ellenberg J, Pepperkok R

Nature protocols, 2007

doi:10.1038/nprot.2006.483.

Production of siRNA- and cDNA-transfected cell arrays on noncoated chambered coverglass for high-content screening microscopy in living cells

Erfle H, Pepperkok R

Methods in molecular biology (Clifton, N.J.), 2007

doi:10.1385/1-59745-165-7:155.

Birth and life of tissue macrophages and their migration in embryogenesis and inflammation in medaka

Grabher C, Cliffe A, Miura K, Hayflick J, Pepperkok R, Rørth P, Wittbrodt J

Journal of leukocyte biology, 2007

doi:10.1189/jlb.0806526.

High-content microscopy identifies new neurite outgrowth regulators

Laketa V, Simpson JC, Bechtel S, Wiemann S, Pepperkok R

Molecular biology of the cell, 2007

doi:10.1091/mbc.e06-08-0666.

Membrane dynamics in the early secretory pathway

Robinson DG, Herranz MC, Bubeck J, Pepperkok R, Ritzenthaler C

Critical reviews in plant sciences, 2007

doi:10.1080/07352680701495820.

Maturation of the mammalian secretome

Simpson JC, Mateos A, Pepperkok R

Genome biology, 2007

doi:10.1186/gb-2007-8-4-211.

Analysis of intraviral protein-protein interactions of the SARS coronavirus ORFeome

von Brunn A, Teepe C, Simpson JC, Pepperkok R, Friedel CC, Zimmer R, Roberts R, Baric R, Haas J

PloS one, 2007

doi:10.1371/journal.pone.0000459.

A role for kinesin-2 in COPI-dependent recycling between the ER and the Golgi complex

Stauber T, Simpson JC, Pepperkok R, Vernos I

Current biology : CB, 2006

doi:10.1016/j.cub.2006.09.060.

Detection and quantification of protein-microtubules interactions using green fluorescent protein photoconversion.

Brunet S, Zimmermann T, Reynaud EG, Vernos I, Karsenti E, Pepperkok R

Traffic (Copenhagen, Denmark), 2006

doi:10.1111/j.1600-0854.2006.00463.x.

High-throughput fluorescence microscopy for systems biology

Pepperkok R, Ellenberg J

Nature reviews. Molecular cell biology, 2006

doi:10.1038/nrm1979.

Sterols regulate ER-export dynamics of secretory cargo protein ts-O45-G

Runz H, Miura K, Weiss M, Pepperkok R

The EMBO journal, 2006

doi:10.1038/sj.emboj.7601205.

Protein kinase WNK3 increases cell survival in a caspase-3-dependent pathway

Veríssimo F, Silva E, Morris JD, Pepperkok R, Jordan P

Oncogene, 2006

doi:10.1038/sj.onc.1209449.

High-throughput RNAi screening by time-lapse imaging of live human cells.

Neumann B, Held M, Liebel U, Erfle H, Rogers P, Pepperkok R, Ellenberg J

Nature methods, 2006

doi:10.1038/nmeth876.

Calcium-dependent regulation of NF-(kappa)B activation in cystic fibrosis airway epithelial cells

Tabary O, Boncoeur E, de Martin R, Pepperkok R, Clément A, Schultz C, Jacquot J

Cellular signalling, 2006

doi:10.1016/j.cellsig.2005.06.004.

Biogenesis of tubular ER-to-Golgi transport intermediates

Simpson JC, Nilsson T, Pepperkok R

Molecular biology of the cell, 2006

doi:10.1091/mbc.e05-06-0580.

Systematic Subcellular Localization of Novel Proteins

Simpson JC, Pepperkok R

2006

doi:10.1016/B978-012164730-8/50140-4.

[Laser nanosurgery in cell biology]

Colombelli J, Pepperkok R, Stelzer EH, Reynaud EG

Medecine sciences : M/S, 2006

doi:10.1051/medsci/20062267651.

Secretory cargo regulates the turnover of COPII subunits at single ER exit sites.

Forster R, Weiss M, Zimmermann T, Reynaud EG, Verissimo F, Stephens DJ, Pepperkok R

Current biology : CB, 2006

doi:10.1016/j.cub.2005.11.076.

The LIFEdb database in 2006

Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S

Nucleic acids research, 2006

doi:10.1093/nar/gkj139.

Time-lapse microscopy-based genome wide RNAI screening in live human cells.

Neumann B, Held M, Liebel U, Erfle H, Rogers P, Pepperkok R, Ellenberg J

2006 3RD IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING: MACRO TO NANO, VOLS 1-3, 2006

doi:10.1109/ISBI.2006.1624898.

The subcellular localization of the mammalian proteome comes a fraction closer

Simpson JC, Pepperkok R

Genome biology, 2006

doi:10.1186/gb-2006-7-6-222.

In vivo selective cytoskeleton dynamics quantification in interphase cells induced by pulsed ultraviolet laser nanosurgery

Colombelli J, Reynaud EG, Rietdorf J, Pepperkok R, Stelzer EH

Traffic (Copenhagen, Denmark), 2005

doi:10.1111/j.1600-0854.2005.00334.x.

Functional profiling: from microarrays via cell-based assays to novel tumor relevant modulators of the cell cycle

Arlt D, Huber W, Liebel U, Schmidt C, Majety M, Sauermann M, Rosenfelder H, Bechtel S, Mehrle A, Bannasch D, Schupp I, Seiler M, Simpson JC, Hahne F, Moosmayer P, Ruschhaupt M, Guilleaume B, Wellenreuther R, Pepperkok R, Sültmann H, Poustka A, Wiemann S

Cancer research, 2005

doi:10.1158/0008-5472.CAN-05-0642.

Imaging epidermal growth factor receptor phosphorylation in human colorectal cancer cells and human tissues

Keese M, Magdeburg RJ, Herzog T, Hasenberg T, Offterdinger M, Pepperkok R, Sturm JW, Bastiaens PI

The Journal of biological chemistry, 2005

doi:10.1074/jbc.m504485200.

Translocation biosensors to study signal-specific nucleo-cytoplasmic transport, protease activity and protein-protein interactions

Knauer SK, Moodt S, Berg T, Liebel U, Pepperkok R, Stauber RH

Traffic (Copenhagen, Denmark), 2005

doi:10.1111/j.1600-0854.2005.00298.x.

Dynamics of COPII vesicles and the Golgi apparatus in cultured Nicotiana tabacum BY-2 cells provides evidence for transient association of Golgi stacks with endoplasmic reticulum exit sites

Yang YD, Elamawi R, Bubeck J, Pepperkok R, Ritzenthaler C, Robinson DG

The Plant cell, 2005

doi:10.1105/tpc.104.026757.

Gamma-BAR, a novel AP-1-interacting protein involved in post-Golgi trafficking

Neubrand VE, Will RD, Möbius W, Poustka A, Wiemann S, Schu P, Dotti CG, Pepperkok R, Simpson JC

The EMBO journal, 2005

doi:10.1038/sj.emboj.7600600.

Novel cancer relevant cell cycle modulators identified in automated cell-based assays

Arlt D, Huber W, Sauermann M, Majety M, Hahne F, Pepperkok R, Poustka A, Wiemann S

European journal of cell biology, 2005

doi:.

Live imaging of bidirectional traffic from the ERGIC

Ben-Tekaya H, Miura K, Pepperkok R, Hauri HP

Journal of cell science, 2005

doi:10.1242/jcs.01615.

Arrays of transfected mammalian cells for high content screening microscopy

Erfle H, Pepperkok R

Methods in enzymology, 2005

doi:10.1016/s0076-6879(05)04001-2.

Bioinformatic "Harvester": a search engine for genome-wide human, mouse, and rat protein resources

Liebel U, Kindler B, Pepperkok R

Methods in enzymology, 2005

doi:10.1016/s0076-6879(05)04003-6.

IR micro spectroscopy of live cells

Moss DA, Keese M, Pepperkok R

Vibrational Spectroscopy, 2005

doi:10.1016/j.vibspec.2005.04.004.

Imaging platforms for measurement of membrane trafficking.

Pepperkok R, Simpson JC, Rietdorf J, Cetin C, Liebel U, Terjung S, Zimmermann T

Methods in enzymology, 2005

doi:10.1016/s0076-6879(05)04002-4.

Human Lsg1 defines a family of essential GTPases that correlates with the evolution of compartmentalization

Reynaud EG, Andrade MA, Bonneau F, Ly TB, Knop M, Scheffzek K, Pepperkok R

BMC biology, 2005

doi:10.1186/1741-7007-3-21.

EAMNET - a resource and teaching framework for advanced light microscopy

Terjung S, Pepperkok R, Ankerhold R, Caiolfa VR, Castel S, Majer P, Geiger B, Luini A, Salamero J, Shorte S, Small JV

European journal of cell biology, 2005

doi:.

Coupling of ER exit to microtubules through direct interaction of COPII with dynactin

Watson P, Forster R, Palmer KJ, Pepperkok R, Stephens DJ

Nature cell biology, 2005

doi:10.1038/ncb1206.

Regulation of microtubule-dependent recycling at the trans-Golgi network by Rab6A and Rab6A'

Young J, Stauber T, del Nery E, Vernos I, Pepperkok R, Nilsson T

Molecular biology of the cell, 2005

doi:10.1091/mbc.e04-03-0260.

Characterization of the TPX2 domains involved in microtubule nucleation and spindle assembly in Xenopus egg extracts.

Brunet S, Sardon T, Zimmerman T, Wittmann T, Pepperkok R, Karsenti E, Vernos I

Molecular biology of the cell, 2004

doi:10.1091/mbc.e04-05-0385.

High-content screening microscopy identifies novel proteins with a putative role in secretory membrane traffic

Starkuviene V, Liebel U, Simpson JC, Erfle H, Poustka A, Wiemann S, Pepperkok R

Genome research, 2004

doi:10.1101/gr.2658304.

From ORFeome to biology: a functional genomics pipeline

Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A

Genome research, 2004

doi:10.1101/gr.2576704.

siRNA cell arrays for high-content screening microscopy

Erfle H, Simpson JC, Bastiaens PI, Pepperkok R

BioTechniques, 2004

doi:10.2144/04373RT01.

'Harvester': a fast meta search engine of human protein resources

Liebel U, Kindler B, Pepperkok R

Bioinformatics (Oxford, England), 2004

doi:10.1093/bioinformatics/bth146.

Confocal microscopy analysis of native, full length and B-domain deleted coagulation factor VIII trafficking in mammalian cells

Becker S, Simpson JC, Pepperkok R, Heinz S, Herder C, Grez M, Seifried E, Tonn T

Thrombosis and haemostasis, 2004

doi:10.1267/thro04070023.

Differential effects of a GTP-restricted mutant of Sar1p on segregation of cargo during export from the endoplasmic reticulum

Stephens DJ, Pepperkok R

Journal of cell science, 2004

doi:10.1242/jcs.01269.

Automatic identification of subcellular phenotypes on human cell arrays

Conrad C, Erfle H, Warnat P, Daigle N, Lörch T, Ellenberg J, Pepperkok R, Eils R

Genome research, 2004

doi:10.1101/gr.2383804.

LIFEdb: a database for functional genomics experiments integrating information from external sources, and serving as a sample tracking system

Bannasch D, Mehrle A, Glatting KH, Pepperkok R, Poustka A, Wiemann S

Nucleic acids research, 2004

doi:10.1093/nar/gkh022.

A microscope-based screening platform for large-scale functional protein analysis in intact cells

Liebel U, Starkuviene V, Erfle H, Simpson JC, Poustka A, Wiemann S, Pepperkok R

FEBS letters, 2003

doi:10.1016/s0014-5793(03)01197-9.

Spectral imaging and its applications in live cell microscopy.

Zimmermann T, Rietdorf J, Pepperkok R

FEBS letters, 2003

doi:10.1016/s0014-5793(03)00521-0.

Localizing the proteome

Simpson JC, Pepperkok R

Genome biology, 2003

doi:10.1186/gb-2003-4-12-240.

The German cDNA network: cDNAs, functional genomics and proteomics

Wiemann S, Bechtel S, Bannasch D, Pepperkok R, Poustka A, German cDNA Network

Journal of structural and functional genomics, 2003

doi:10.1023/a:1026148428520.

CDNAs for functional genomics and proteomics: the German Consortium

Wiemann S, Mehrle A, Bechtel S, Wellenreuther R, Pepperkok R, Poustka A, German cDNA Consortium

Comptes rendus biologies, 2003

doi:10.1016/j.crvi.2003.09.036.

Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells

Gruss OJ, Wittmann M, Yokoyama H, Pepperkok R, Kufer T, Silljé H, Karsenti E, Mattaj IW, Vernos I

Nature cell biology, 2002

doi:10.1038/ncb870.

Spectral imaging and linear un-mixing enables improved FRET efficiency with a novel GFP2-YFP FRET pair.

Zimmermann T, Rietdorf J, Girod A, Georget V, Pepperkok R

FEBS letters, 2002

doi:10.1016/s0014-5793(02)03508-1.

Inhibitors of COP-mediated transport and cholera toxin action inhibit simian virus 40 infection

Richards AA, Stang E, Pepperkok R, Parton RG

Molecular biology of the cell, 2002

doi:10.1091/mbc.01-12-0592.

Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells

Runz H, Rietdorf J, Tomic I, de Bernard M, Beyreuther K, Pepperkok R, Hartmann T

The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002

doi:10.1523/JNEUROSCI.22-05-01679.2002.

Imaging of procollagen transport reveals COPI-dependent cargo sorting during ER-to-Golgi transport in mammalian cells

Stephens DJ, Pepperkok R

Journal of cell science, 2002

doi:.

A fully automated high content screening system for cell based genome analyses

Liebel U, Pepperkok R

2002

doi:.

The Spir actin organizers are involved in vesicle transport processes

Kerkhoff E, Simpson JC, Leberfinger CB, Otto IM, Doerks T, Bork P, Rapp UR, Raabe T, Pepperkok R

Current biology : CB, 2001

doi:10.1016/s0960-9822(01)00602-9.

The many ways to cross the plasma membrane

Stephens DJ, Pepperkok R

Proceedings of the National Academy of Sciences of the United States of America, 2001

doi:10.1073/pnas.081065198.

Illuminating the secretory pathway: when do we need vesicles?

Stephens DJ, Pepperkok R

Journal of cell science, 2001

doi:.

Being in the right location at the right time

Pepperkok R, Simpson JC, Wiemann S

Genome biology, 2001

doi:10.1186/gb-2001-2-9-reviews1024.

Illuminating the human genome

Simpson JC, Neubrand VE, Wiemann S, Pepperkok R

Histochemistry and cell biology, 2001

doi:10.1007/s004180000236.

Observing proteins in their natural habitat: the living cell

Bastiaens PI, Pepperkok R

Trends in biochemical sciences, 2000

doi:10.1016/s0968-0004(00)01714-x.

Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing

Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S

EMBO reports, 2000

doi:10.1093/embo-reports/kvd058.

Breaking the COPI monopoly on Golgi recycling

Storrie B, Pepperkok R, Nilsson T

Trends in cell biology, 2000

doi:10.1016/s0962-8924(00)01818-3.

COPI-coated ER-to-Golgi transport complexes segregate from COPII in close proximity to ER exit sites

Stephens DJ, Lin-Marq N, Pagano A, Pepperkok R, Paccaud JP

Journal of cell science, 2000

doi:.

Intracellular distribution of mammalian protein kinase A catalytic subunit altered by conserved Asn2 deamidation

Pepperkok R, Hotz-Wagenblatt A, König N, Girod A, Bossemeyer D, Kinzel V

The Journal of cell biology, 2000

doi:10.1083/jcb.148.4.715.

Fluorescence microscopy of living vertebrate cells

Pepperkok R, Shima G

2000

doi:.

Immunofluorescence microscopy

Pepperkok R, Girod A, Simpson J, Rietdorf J

2000

doi:.

The p24 family member p23 is required for early embryonic development

Denzel A, Otto F, Girod A, Pepperkok R, Watson R, Rosewell I, Bergeron JJ, Solari RC, Owen MJ

Current biology : CB, 2000

doi:10.1016/s0960-9822(99)00266-3.

COPI vesicles accumulating in the presence of a GTP restricted arf1 mutant are depleted of anterograde and retrograde cargo

Pepperkok R, Whitney JA, Gomez M, Kreis TE

Journal of cell science, 2000

doi:.

Illuminating cellular structure and function in the early secretory pathway by multispectral 3D imaging in living cells

Rietdorf J, Stephens DJ, Squire A, Simpson J, Shima DT, Paccaud JP, Bastiaens PIH, Pepperkok R

OPTICAL DIAGNOSTICS OF LIVING CELLS III, 2000

doi:10.1117/12.384216.

Dyskerin localizes to the nucleolus and its mislocalization is unlikely to play a role in the pathogenesis of dyskeratosis congenita

Heiss NS, Girod A, Salowsky R, Wiemann S, Pepperkok R, Poustka A

Human molecular genetics, 1999

doi:10.1093/hmg/8.13.2515.

Evidence for a COP-I-independent transport route from the Golgi complex to the endoplasmic reticulum

Girod A, Storrie B, Simpson JC, Johannes L, Goud B, Roberts LM, Lord JM, Nilsson T, Pepperkok R

Nature cell biology, 1999

doi:10.1038/15658.

New imaging methods illuminating cellular structure and function

Pepperkok R

EUROPEAN JOURNAL OF CANCER, 1999

doi:10.1016/S0959-8049(99)80630-3.

Intracellular movement of green fluorescent protein-tagged phosphatidylinositol 3-kinase in response to growth factor receptor signaling

Gillham H, Golding MC, Pepperkok R, Gullick WJ

The Journal of cell biology, 1999

doi:10.1083/jcb.146.4.869.

Simultaneous detection of multiple green fluorescent proteins in live cells by fluorescence lifetime imaging microscopy

Pepperkok R, Squire A, Geley S, Bastiaens PI

Current biology : CB, 1999

doi:10.1016/s0960-9822(99)80117-1.

The KDEL retrieval system is exploited by Pseudomonas exotoxin A, but not by Shiga-like toxin-1, during retrograde transport from the Golgi complex to the endoplasmic reticulum

Jackson ME, Simpson JC, Girod A, Pepperkok R, Roberts LM, Lord JM

Journal of cell science, 1999

doi:.

Segregation of COPI-rich and anterograde-cargo-rich domains in endoplasmic-reticulum-to-Golgi transport complexes

Shima DT, Scales SJ, Kreis TE, Pepperkok R

Current biology : CB, 1999

doi:10.1016/s0960-9822(99)80365-0.

KDEL receptor (Erd2p)-mediated retrograde transport of the cholera toxin A subunit from the Golgi involves COPI, p23, and the COOH terminus of Erd2p

Majoul I, Sohn K, Wieland FT, Pepperkok R, Pizza M, Hillemann J, Söling HD

The Journal of cell biology, 1998

doi:10.1083/jcb.143.3.601.

Three distinct steps in transport of vesicular stomatitis virus glycoprotein from the ER to the cell surface in vivo with differential sensitivities to GTP gamma S

Pepperkok R, Lowe M, Burke B, Kreis TE

Journal of cell science, 1998

doi:.

Electroporation of cells

Herr S, Pepperkok R, Saffrich R, Wiemann S and Ansorge W

1998

doi:.

Cellular microbiochemistry

Pepperkok R, Rosorius O, Scheel J

1998

doi:10.1007/978-3-642-80343-7_8.

Computer-automated and semiautomated capillary microinjection of macromolecules into living cells

Pepperkok R, Saffrich R, Ansorge W

1998

doi:.

Visualization of ER-to-Golgi transport in living cells reveals a sequential mode of action for COPII and COPI

Scales SJ, Pepperkok R, Kreis TE

Cell, 1997

doi:10.1016/s0092-8674(00)80379-7.

Dissociation of coatomer from membranes is required for brefeldin A-induced transfer of Golgi enzymes to the endoplasmic reticulum

Scheel J, Pepperkok R, Lowe M, Griffiths G, Kreis TE

The Journal of cell biology, 1997

doi:10.1083/jcb.137.2.319.

Microinjection and electroporation of macromolecules into live cells

Pepperkok R

1996

doi:10.1007/978-3-642-57783-3_7.

Immunocytochemical localization of beta-COP to the ER-Golgi boundary and the TGN

Griffiths G, Pepperkok R, Locker JK, Kreis TE

Journal of cell science, 1995

doi:.

DIRECT VISUALIZATION OF DNA-REPLICATION SITES IN LIVING CELLS BY MICROINJECTION OF FLUORESCEIN-CONJUGATED DUTPS

PEPPERKOK R, ANSORGE W

METHODS IN MOLECULAR AND CELLULAR BIOLOGY, 1995

doi:.

REGULATION OF G(1) PROGRESSION BY E2A AND ID HELIX-LOOP-HELIX PROTEINS

PEVERALI FA, RAMQVIST T, SAFFRICH R, PEPPERKOK R, BARONE MV, PHILIPSON L

EMBO JOURNAL, 1994

doi:10.1002/j.1460-2075.1994.tb06749.x.

Regulation of G1 progression by E2A and Id helix-loop-helix proteins

Peverali FA, Ramqvist T, Saffrich R, Pepperkok R, Barone MV, Philipson L

The EMBO journal, 1994

doi:10.1002/j.1460-2075.1994.tb06749.x.

Id proteins control growth induction in mammalian cells

Barone MV, Pepperkok R, Peverali FA, Philipson L

Proceedings of the National Academy of Sciences of the United States of America, 1994

doi:10.1073/pnas.91.11.4985.

The intracellular mobility of a viral membrane glycoprotein measured by confocal microscope fluorescence recovery after photobleaching

Storrie B, Pepperkok R, Stelzer EH, Kreis TE

Journal of cell science, 1994

doi:.

CASEIN KINASE-II IS REQUIRED FOR TRANSITION OF G(0)/G(1), EARLY G(1), AND G(1)/S PHASES OF THE CELL-CYCLE

PEPPERKOK R, LORENZ P, ANSORGE W, PYERIN W

JOURNAL OF BIOLOGICAL CHEMISTRY, 1994

doi:.

The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells

Twamley-Stein GM, Pepperkok R, Ansorge W, Courtneidge SA

Proceedings of the National Academy of Sciences of the United States of America, 1993

doi:10.1073/pnas.90.16.7696.

Beta-COP is essential for biosynthetic membrane transport from the endoplasmic reticulum to the Golgi complex in vivo

Pepperkok R, Scheel J, Horstmann H, Hauri HP, Griffiths G, Kreis TE

Cell, 1993

doi:10.1016/0092-8674(93)90295-2.

Regulation of the cell cycle by the cdk2 protein kinase in cultured human fibroblasts

Pagano M, Pepperkok R, Lukas J, Baldin V, Ansorge W, Bartek J, Draetta G

The Journal of cell biology, 1993

doi:10.1083/jcb.121.1.101.

Import of firefly luciferase into mammalian peroxisomes in vivo requires nucleoside triphosphates

Soto U, Pepperkok R, Ansorge W, Just WW

Experimental cell research, 1993

doi:10.1006/excr.1993.1059.

System for quantitation of gene expression in single cells by computerized microimaging: application to c-fos expression after microinjection of anti-casein kinase II antibody

Pepperkok R, Herr S, Lorenz P, Pyerin W, Ansorge W

Experimental cell research, 1993

doi:10.1006/excr.1993.1034.

A fully automated image acquisition and analysis system for low light level fluorescence microscopy

Herr S, Bastian T, Pepperkok R, Boulin C, Ansorge W

1993

doi:.

β-COP, a Coat Protein of Nonclathrin-Coated Vesicles of the Golgi Complex, is Involved in Transport of Vesicular Stomatitis Virus Glycoprotein

Duden R, Storrie B, Pepperkok R, Scheel J, Joggerst-Thomalla B, Sawyer A, Horstmann H, Griffiths G, Kreis T

1993

doi:10.1007/978-3-662-02928-2_26.

CLIP-170, a Cytoplasmic Linker Protein Mediating Interaction of Endosomes with Microtubules

Scheel J, Rickard J, Pierre P, Hennig D, Karecla P, Pepperkok R, Joggerst-Thomalla B, Sawyer A, Parton R, Kreis T

1993

doi:10.1007/978-3-662-02928-2_29.

Early cell growth stimulation is inhibited by casein kinase II antisense oligodeoxynucleotides

Pyerin W, Pepperkok R, Ansorge W, Lorenz P

Annals of the New York Academy of Sciences, 1992

doi:10.1111/j.1749-6632.1992.tb21091.x.

Mammalian nuclei contain foci which are highly enriched in components of the pre-mRNA splicing machinery

Carmo-Fonseca M, Tollervey D, Pepperkok R, Barabino SM, Merdes A, Brunner C, Zamore PD, Green MR, Hurt E, Lamond AI

The EMBO journal, 1991

doi:10.1002/j.1460-2075.1991.tb07936.x.

Single cell assay with an automated capillary microinjection system

Pepperkok R, Schneider C, Philipson L, Ansorge W

Cytotechnology, 1991

doi:10.1007/bf00736821.

Regulation of microtubule dynamics and nucleation during polarization in MDCK II cells

Bré MH, Pepperkok R, Hill AM, Levilliers N, Ansorge W, Stelzer EH, Karsenti E

The Journal of cell biology, 1990

doi:10.1083/jcb.111.6.3013.

Cell proliferation inhibited by MyoD1 independently of myogenic differentiation

Sorrentino V, Pepperkok R, Davis RL, Ansorge W, Philipson L

Nature, 1990

doi:10.1038/345813a0.

An antibody against secretogranin I (chromogranin B) is packaged into secretory granules

Rosa P, Weiss U, Pepperkok R, Ansorge W, Niehrs C, Stelzer EH, Huttner WB

The Journal of cell biology, 1989

doi:10.1083/jcb.109.1.17.

Automated Sanger DNA sequencing with one label in less than four lanes on gel

Ansorge W, Voss H, Wirkner U, Schwager C, Stegemann J, Pepperkok R, Zimmermann J, Erfle H

Journal of biochemical and biophysical methods, 1989

doi:10.1016/0165-022x(89)90080-8.

Automatic microinjection system facilitates detection of growth inhibitory mRNA

Pepperkok R, Zanetti M, King R, Delia D, Ansorge W, Philipson L, Schneider C

Proceedings of the National Academy of Sciences of the United States of America, 1988

doi:10.1073/pnas.85.18.6748.

Performance of an automated system for capillary microinjection into living cells

Ansorge W, Pepperkok R

Journal of biochemical and biophysical methods, 1988

doi:10.1016/0165-022x(88)90062-0.