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Dayton Group

Organoid models of neuroendocrine development and cancer

At EMBL from September 2022.

Publications

Pyruvate kinase M1 suppresses development and progression of prostate adenocarcinoma.

Davidson SM, Heyman JE, O’Brien JP, Liu AC, Schmidt DR, Israelsen WJ, Dayton TL, Sehgal R, Bronson RT, Freinkman E, Mak H, Malstrom S, Bellinger G, Carracedo A, Pandolfi PP, Courtney KD, Jha A, DePinho RA, Horner JW, Thomas CJ, Cantley LC, Loda M, Heiden MV

bioRxiv 2021

doi:10.1101/2021.05.09.443334.

Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development.

Mayers JR, Wu C, Clish CB, Kraft P, Torrence ME, Fiske BP, Yuan C, Bao Y, Townsend MK, Tworoger SS, Davidson SM, Papagiannakopoulos T, Yang A, Dayton TL, Ogino S, Stampfer MJ, Giovannucci EL, Qian ZR, Rubinson DA, Ma J, Sesso HD, Gaziano JM, Cochrane BB, Liu S, Wactawski-Wende J, Manson JE, Pollak MN, Kimmelman AC, Souza A, Pierce K, Wang TJ, Gerszten RE, Fuchs CS, Vander Heiden MG, Wolpin BM

Nature medicine 2014

25261994. doi:10.1038/nm.3686.


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