Biological oscillators: design, mechanism, function

Time	Speaker
11:15 – 13:00	Registration & light lunch
13:00 – 14:00	Pre-symposium ‘Oscillator Theory for Biologists’ Workshop (on-site participants only) Board lecture by Hanspeter Herzel – Institute for Theoretical Biology – Humboldt University Berlin, Germany
14:00 – 14:30	Break and change of groups
14:30 – 15:30	Pre-symposium ‘Oscillator Theory for Biologists’ Workshop hands-on part (on-site participants only) Bharath Ananthasubramaniam – Institute for Theoretical Biology –Humboldt University Berlin, Germany Christoph Schmal – Institute for Theoretical Biology – Humboldt University Berlin, Germany Marta Del Olmo – Institute for Theoretical Biology – Humboldt University Berlin, Germany Hanspeter Herzel – Institute for Theoretical Biology – Humboldt University Berlin, Germany
15:30 – 16:00	Coffee Break
15:15 – 16:00	Registration (participants not attending the pre-symposium workshop)
16:00 – 16:15	Opening Remarks Alexander Aulehla – EMBL Heidelberg, Germany AVAILABLE ON DEMAND AFTER LIVE STREAM
	Session 1
	Chair: Alexander Aulehla – EMBL Heidelberg, Germany
16:15- 17:00	Keynote lecture Degenerate mechanisms in oscillator dynamics Eve Marder – Brandeis University, USA (Virtual Speaker) AVAILABLE ON DEMAND AFTER LIVE STREAM
17:00 – 17:30	Rhythms in a changing world Noga Kronfeld-Schor – Tel Aviv University, Israel (Virtual Speaker) AVAILABLE ON DEMAND AFTER LIVE STREAM
17:30 – 17:45	Waves and patterns in the frog egg cytoplasm Lendert Gelens – KU Leuven, Belgium AVAILABLE ON DEMAND AFTER LIVE STREAM
17:45 – 17:50	Technical buffer
17:50 – 18:35	Coffee Break
18:35 – 18:50	But, what are the cells doing? – Image analysis pipeline to follow single cells during somitogenesis in zebrafish embryo Arianne Bercowsky Rama – Swiss Federal Institute of Technology Lausanne, Switzerland AVAILABLE ON DEMAND AFTER LIVE STREAM
18:50 – 19:20	Data modeling on periodic manifolds: applications to circadian rhythms Felix Naef – Swiss Federal Institute of Technology Lausanne, Switzerland
19:20 – 21:00	Dinner in Canteen
21:00 – 22:00	Welcome drinks

Time	Speaker
08:30 – 09:45	Registration & Coffee
	Session 2
	Chair: Ueli Schibler – University of Geneva, Switzerland
09:45 – 10:15	Molecular basis of vertebrate infradian rhythms Takashi Yoshimura – Nagoya University, Japan (Virtual Speaker) AVAILABLE ON DEMAND AFTER LIVE STREAM
10:15 – 10:45	Circadian clock organization in flies stemming from different latitudes. Are weaker clocks the better clocks? Charlotte Förster – University of Würzburg, Germany AVAILABLE ON DEMAND AFTER LIVE STREAM
10:45 – 11:00	A transcriptional oscillator to time skin regeneration Helge Grosshans – Friedrich Miescher Institute for Biomedical Research, Switzerland AVAILABLE ON DEMAND AFTER LIVE STREAM
11:00 – 11:05	Technical buffer
11:05 – 11:45	Coffee Break
11:45 – 12:15	Synchronization of the cell cycle and the circadian clock through bidirectional coupling Albert Goldbeter – Université Libre de Bruxelles, Belgium (Virtual Speaker) AVAILABLE ON DEMAND AFTER LIVE STREAM
12:15 – 12:30	Noisy circadian clocks gate cell division in Anabaena Rinat Arbel-Goren – Weizmann Institute of Science, Israel AVAILABLE ON DEMAND AFTER LIVE STREAM
12:30 – 12:45	Nanostructures instability driven by the reaction-diffusion mechanism Mikhail Kryuchkov – University of Geneva, Switzerland AVAILABLE ON DEMAND AFTER LIVE STREAM
12:45 – 14:15	Lunch break
	Session 3
	Chair: Hanspeter Herzel – Institute for Theoretical Biology – Humboldt University Berlin, Germany
14:15 – 14:45	Merging biological and mathematical network oscillation generation mechanisms Frances K. Skinner – University Health Network, Canada (Virtual Speaker) AVAILABLE ON DEMAND AFTER LIVE STREAM
14:45- 15:00	The Origin and Regulation of Segmentation Clock Oscillation Dynamics in the Mouse Embryo Tomita Takehito – EMBL Heidelberg, Germany AVAILABLE ON DEMAND AFTER LIVE STREAM
15:00 – 15:15	Multiscale, dynamic and spatially-periodic coordination of gene expression in spinal cord progenitor cells Veronica Biga – The University of Manchester, UK AVAILABLE ON DEMAND AFTER LIVE STREAM
15:15 – 15:20	Technical buffer
15:20 – 16:05	Coffee Break
16:05 – 16:35	The pacemaker of the cell cycle oscillator James E. Ferrell – Stanford University School of Medicine, USA (Virtual Speaker) AVAILABLE ON DEMAND AFTER LIVE STREAM
16:35 – 16:50	Xenopus embryo injury initiates calcium waves that travel both within and between embryos via ATP signaling Megan Sperry – Wyss Institute at Harvard University, USA (Virtual Speaker) AVAILABLE ON DEMAND AFTER LIVE STREAM
16:50 – 17:20	Circadian rhythms of gene expression in vivo and in vitro Susan S. Golden – University of California San Diego, USA AVAILABLE ON DEMAND AFTER LIVE STREAM
17:20 – 17:25	Technical buffer
17:25 – 19:25	Poster Session 1 (odd numbers) with snacks
19:25 – 21:00	Dinner in Canteen
21:00 – 22:00	Networking drinks

Time	Speaker
08:30 – 09:45	Registration & Coffee
	Session 4
	Chair: Jordi Garcia-Ojalvo Pompeu Fabra University, Spain
09:45 – 10:15	Roles of Hes1 oscillations in neural stem cells Ryoichiro Kageyama – RIKEN Center for Brain Science Japan (Virtual Speaker) AVAILABLE ON DEMAND AFTER LIVE STREAM
10:15 – 10:45	Measuring human circadian rhythms for precision chronomedicine Francis Albert Lévi – Faculty of Medicine, Paris-Saclay University, France AVAILABLE ON DEMAND AFTER LIVE STREAM
10:45 – 11:00	Cytoskeletal oscillator produces complex wave patterns on the surface of rewired frog oocytes Andrew Goryachev – The University of Edinburgh, UK AVAILABLE ON DEMAND AFTER LIVE STREAM
11:00 – 11:05	Technical buffer
11:05 – 11:45	Coffee Break
11:45 – 12:00	Emergent calcium dynamics in an astrocyte-neuronal network coupled via nitric oxide molecule Bhanu Sharma – South Campus Delhi University, India (Virtual Speaker) AVAILABLE ON DEMAND AFTER LIVE STREAM
12:00 – 12:15	A series of individual transcriptional pulses produces a periodic pattern of Atonal in the Drosophila eye Francois Schweisguth – Institut Pasteur, France AVAILABLE ON DEMAND AFTER LIVE STREAM
12:15 – 12:30	lin-4 functions as a temporal morphogen Christopher Hammell – Cold Spring Harbor Laboratory, USA AVAILABLE ON DEMAND AFTER LIVE STREAM
12:30 – 12:35	Technical buffer
12:35 – 14:00	Lunch break
	Session 5
	Chair: Ueli Schibler – University of Geneva, Switzerland
14:00 – 14:30	Deconstructing the segmentation clock in vitro Olivier Pourquié – Harvard University, USA AVAILABLE ON DEMAND AFTER LIVE STREAM
14:30 – 14:45	p53 oscillatory dynamics optimizes DNA repair efficiency by regulating foci formation Mathias Luidor Heltberg – University of Copenhagen, Denmark AVAILABLE ON DEMAND AFTER LIVE STREAM
14:45 – 15:00	Direct, real time in vivo measurement of distinct circadian clocks in Drosophila Deniz Top – Dalhousie University, Canada AVAILABLE ON DEMAND AFTER LIVE STREAM
15:00 – 15:15	Group photo
15:15 – 16:00	Coffee Break
16:00 – 16:30	Decoding Network Dynamics in Coupled Oscillators István Z. Kiss – Saint Louis University, USA (Virtual Speaker) AVAILABLE ON DEMAND AFTER LIVE STREAM
16:30 – 17:00	Oscillatory dynamics and hippocampal memory operations Laura Colgin – The University of Texas at Austin, USA (Virtual Speaker) AVAILABLE ON DEMAND AFTER LIVE STREAM
17:00 – 17:15	On the robustness of the cyanobacterial circadian clock Sophie de Buyl – Vrije Universiteit Brussel, Belgium AVAILABLE ON DEMAND AFTER LIVE STREAM
17:15 – 17:20	Technical buffer
17:20 – 19:15	Poster Session 2 (even) with snacks
19:15 – 20:45	Dinner in Canteen
20:45 – 21:45	Networking drinks

Time	Speaker
08:30 – 09:45	Registration & Coffee
	Session 6
	Chair: Hanspeter Herzel – Institute for Theoretical Biology – Humboldt University Berlin, Germany
09:45 – 10:15	Differential phase register of Hes1 oscillations with mitoses in breast cancer cells underlies their cell cycle heterogeneity Nancy Papalopolou – University of Manchester, UK AVAILABLE ON DEMAND AFTER LIVE STREAM
10:15 – 10:30	Modelling gene regulation oscillatory dynamics during the cell cycle in single cells Nacho Molina – Institute of Genetics and Molecular and Cellular Biology, France AVAILABLE ON DEMAND AFTER LIVE STREAM
10:30 – 11:00	Oscillations as organizers in bacterial populations Jordi Garcia-Ojalvo – Pompeu Fabra University, Spain AVAILABLE ON DEMAND AFTER LIVE STREAM
11:00 – 11:05	Technical buffer
11:05 – 11:45	Coffee Break
11:45 – 12:00	Functional analysis of multiscale oscillations in insect olfactory receptor neurons Monika Stengl – University of Kassel, Germany AVAILABLE ON DEMAND AFTER LIVE STREAM
12:00 – 12:15	Signalling centre vortices control periodic activation waves and coordinate Dictyostelium morphogenesis Hugh Ford – University College London, UK AVAILABLE ON DEMAND AFTER LIVE STREAM
12:15 – 12:30	Stress discrimination by body-wide, stochastic DAF-16/FoxO nuclear translocation pulses Burak Demirbas – AMOLF, The Netherlands AVAILABLE ON DEMAND AFTER LIVE STREAM
12:30 – 13:15	Keynote lecture Mechanism for the self-termination of paroxysmal rhythms Leon Glass – McGill University, Canada (Virtual Speaker) AVAILABLE ON DEMAND AFTER LIVE STREAM
13:15 – 13:30	Closing Remarks and Poster Prize
13:30 – 14:00	Packed Lunch
14:00	Departure

Accommodation is not included in the conference registration fee.

As further changes in our events are possible due to COVID-19, you should book flights, trains and hotels with flexible options and favorable cancellation conditions.

The hotels below have rooms on hold for participants until Saturday 5 February 2022, in some cases at special rates. Please quote the booking code EES22-01 and confirm the exact price of the room with the hotel directly.

Hotel Anlage	Hotel ibis Heidelberg	Premier Inn Heidelberg City
Hotel Bayrischer Hof	ISG Hotel	Staycity Aparthotel Heidelberg
B&B Hotel	Leonardo Hotel Heidelberg City Centre	Steffi’s Hostel Heidelberg
Exzellenz Hotel & Boarding House	Meininger Heidelberg	Hotel Vier Jahreszeiten Heidelberg
Hotel Monpti

Conference Shuttle Buses

Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back, mornings and evenings.

Download the bus schedule

The bus stops for this conference are:

• Kurfürsten-Anlage (Opposite Train Station)
• Hotel Premier, Kurfürsten-Anlage 23
• Leonardo Hotel (Bergheimer Str.)
• Neckarmuenzplatz
• Peterskirche
• ISG Hotel

View Conference shuttle bus stops and hotels for this conference on a larger map.

Further details

Address: EMBL, Meyerhofstraße 1, 69117 Heidelberg, Germany. For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue. For information about accommodation and local transportation please refer to the FAQ page.

Catering

All meals and coffee breaks are included in the registration fee. Our catering staff will prepare a wide variety of vegetarian meals, meat and fish dishes, soups, pasta, fresh fruit and vegetables, as well as a variety of desserts.

Please wear your badge at all times when serving yourself.

No food or drinks are allowed in the auditorium.

Charging lockers

There are lockers available next to the stairs leading down into the Auditorium. You will find some of those equipped with sockets to charge your smartphone/tablet etc.

Electricity and charging station

In most places the electricity is 220 volts AC (50 cycles). An adaptor and a plug that fits the German socket may be needed for your appliances/laptop (i.e. American, Japanese, etc.). A USB charging station for electronic devices is available at the registration desk.

EMBL merchandise

EMBL Merchandise is available on Mon – Thu (9 am – 12 pm). If you are interested in purchasing an EMBL souvenir (products presented in the glass display in the registration area), please ask at the registration desk for more information.

Health and safety notes

Please read EMBL’s COVID-19 safety policy for on-site events.
Do not smoke in any EMBL building.
Eating and drinking is prohibited in the Auditorium and all laboratories.
Do not enter any restricted areas or the laboratories unless instructed to do so.

If first aid is required …

• The first aid room is located next to the ATC Registration Desk (room 10- 205).
• Dial the Emergency number 222 from any EMBL internal phone only.
• Where is the accident? What happened? How many injured?
• Emergency number 06221-387 7821 from mobile phones.
• Please report all accidents to the conference officer at the registration desk.

In case of fire …

• Press the nearest fire alarm button or the Emergency number 222 from any internal phone.
• A loud fire alarm will go off if an evacuation is required. On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points
• Do not use the lifts.

Beyond first aid…

Please remember to bring your own medication, if needed, to the conference. Note that the next pharmacy is a 4-minute drive from the EMBL, but for many medications you will be required to see a doctor to get a prescription.

Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg. In any case, the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary.

Internet

Wi-Fi is available everywhere on the premises (no password required), just log on to ATC-Guest. The eduroam network (secure, world-wide roaming access service developed for the international research and education community) is also available.

Lost and found

‘’Lost and Found’’ are kept at the registration desk until the end of the conference.

Luggage

There are lockers available on-site to store your luggage, which require a 2 EURO coin to operate. There is another luggage room on level E0, which is free to use but remains unlocked during the conference.

Nursing room

There is a nursing room available in the ATC Rooftop Lounge on level A29.

Photography

During the conference an EMBL Photographer may be taking photographs. If you would not like to appear in these, please inform the photographer or a member of the Course and Conference Office.

Printing

We can help print your boarding passes/train tickets. Please send it to events@embl.de and collect your print-outs at the registration desk.

Room for prayer, yoga and meditation

There is a room for prayer, mediation and yoga located on level E0 behind the Auditorium. Please be respectful of other participants using the room.

Sightseeing

A variety of activities in Heidelberg can be found on this website: www.heidelberg-marketing.com

Travel to and from the venue

During the event we provide conference shuttle busses to and from EMBL. In addition, there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time. Information on the conference shuttle busses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page.

Useful German expressions

English	German
Hello	Hallo
Goodbye	Auf Wiedersehen
Good morning	Guten Morgen
Good afternoon	Guten Tag
Good evening	Guten Abend
Good night	Gute Nacht
I’m sorry	Tut mir leid
Excuse me…	Entschuldigen Sie
How are you?	Wie gehts?
I’m fine thanks. And you?	Mir geht es gut , danke, und dir/Ihnen?
What is your name	Wie heisst du? Wie heissen Sie?
My name is	Ich heisse
Do you speak English	Sprechen Sie Englisch?
I don’t understand	Ich verstehe nicht
Please speak more slowly	Können Sie bitte langsamer sprechen
Thank you	Dankeschön
Where is the toilet?	Wo ist die Toilette?
Please call me a taxi	Bitte rufen Sie mir ein Taxi
How do I get to….?	Wie komme ich zum/zur…..?
A beer/two beers please	Ein Bier/zwei Bier bitte
A glass of red/white wine please	Ein Glas Rot/Weisswein bitte
The menu, please	Die Speisekarte, bitte
Is there a local speciality?	Gibt es eine Spezialität aus dieser Gegend?
I’m Vegetarian	Ich bin Vegetarier
It was delicious	Es war hervorragend
The bill, please	Die Rechnung, bitte
I have a headache	Ich habe Kopfschmerzen
I have a sore throat	Ich habe Halsschmerzen
My stomach hurts	Ich habe Magenschmerzen
I’m allergic to	Ich bin allergisch gegen
I need a doctor who speaks English	Gibt es einen Arzt, der Englisch spricht?

What’s included?

• Access to all the livestreamed talks
• Video library of the recorded talks during and after the event
• Facility to submit questions

Please note that only on-site participants are able to submit abstracts and participate in the poster sessions.

Event platform

We are using an event platform for this conference. More information about the platform will be shared ahead of the conference.

Guidelines

• You are encouraged to tweet and post about the event.
• Tweet unless the speaker specifically says otherwise, but be mindful of unpublished data. 
• Please do not capture, transmit or redistribute data presented at the meeting.
• Do not broadcast the conference to unregistered participants.

Additional information can be found in our Code of Conduct.

Health and well-being

It is important to stay healthy and move around, especially when you are attending an event virtually. We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event.

How to ask questions

Please use the Q&A function in the event platform.

If you have any other questions, you can go to the Help Desk in the event platform. Click on ‘more’ on the top menu and click Help Desk. 

Time zone

The programme is planned based on the Europe/Berlin time zone, unless otherwise stated. Please take your time zone into consideration when planning your attendance.

COVID-19 related questions

What do I need to bring in order to access the event?

• Negative antigen / PCR COVID-19 test, not older than 24 h for antigen and 48 h for PCR tests (only on day 1)
• Valid proof of vaccination / recovery and an ID document ready when coming to the event venue. 
• FFP2 mask

Do I need to show a negative test for every day of the event?

No, you will need to have a valid negative test upon arrival on your first day of attendance only. Antigen tests are valid for 24 h and PCR tests are valid for 48 h. Please see FAQ on testing in Heidelberg for more information on finding a test centre.

What kind of masks are allowed onsite?

Only FFP2 masks are allowed for indoors use and must be worn during the whole event (except while eating or drinking during the breaks).

What counts as proof of vaccination?

1. Your proof of vaccination must show that you are fully vaccinated against SARS-CoV-2. To be considered fully vaccinated, you need to have received one or more of the vaccines specified on the website of the Paul Ehrlich Institute. Furthermore, it is necessary that

• either the vaccine/s you received were administered in the number of doses required for full protection, as specified on the website of the Paul Ehrlich Institute above, and 14 days have elapsed since the last required dose of the vaccine was administered,
• or, if you have recovered from a SARS-CoV-2 infection, you have received one dose of vaccine. In this case, in order to prove you are fully protected, you must show proof that you were infected with COVID-19 prior to being vaccinated. For this purpose, you need to show a positive result of a PCR test. 

2. Your proof of vaccination must include the following information:

• your personal details (at least your given name and family name and date of birth, and the number of the passport or other official photo-ID document to be presented at passport control) 
• the date/s of vaccination and number of vaccination doses
• the name/s of the vaccine/s
• the name of the disease against which you were vaccinated
• distinctive features which show the identity of the person or institution responsible for administering the vaccination or issuing the certificate (e.g. an official logo or name of the issuer).

3. Your proof of vaccination must be written in German, English, French, Italian or Spanish.

Proof is accepted in paper or digital form, provided it meets the criteria listed under points 1, 2 and 3. Photographs of paper documents do not count as valid digital proof for the purposes of checks by the transport company or by the police authorities conducting border controls. Digital documentation needs to have been issued electronically by the authorised issuer and transmitted electronically to the authorised holder.

Please note that these are general requirements pursuant to the Coronavirus-Einreiseverordnung. For a digital COVID certificate in line with the EU Regulation on the EU Digital COVID Certificate, additional requirements may have to be met. Further information can be found on the Coronavirus: Frequently Asked Questions website of the German Federal Ministry of the Interior and Community

Which Covid-19 vaccines are recognised in Germany?

Regardless if you are coming from an EU country, please check the Paul Ehrlich Institute website for recognised vaccines to see if your vaccination status is considered valid in Germany. You will find information such as which vaccines (and combinations) are approved, the number of doses required for a complete vaccination protection and the length of time that must pass after vaccination.

What counts as proof of recovery?

The test to prove the previous infection must have been carried out by laboratory diagnostics using nucleic acid detection (PCR, PoC-PCR or other methods of nucleic acid amplification technology). At least 28 days must have passed since getting a positive test. Information on recovery can be found (in German) on the Robert Koch Institute website.

How long is the proof of vaccination valid in Germany?

As of 1 February 2022, the validity of vaccination certificates in Germany is 270 days (roughly 9 months), if no booster vaccination has been administered after a completed basic immunisation.

How long is the proof of recovery valid in Germany?

The validity of proof of recovery in Germany is 90 days (roughly 3 months). At least 28 days must have passed since getting a positive test. 

Do I need to register and quarantine?

If you are arriving from a high-risk area, yes, you have to register at the travel portal (www.einreiseanmeldung.de) before entering the country. You must carry the confirmation with you, but you do not need to quarantine. It is important that you upload your proof of vaccination or recovery at the same time, otherwise you would need to quarantine on arrival.The list of countries marked as a high-risk area are regularly updated on the Robert Koch Institute website. You can find additional information on the obligation to register and exemptions in the FAQs on Digital Registration on Entry, the obligation to furnish proof and quarantine on entry.

I am not a EU resident, will my proof of vaccination / recovery be accepted?

Participants travelling from a non-EU country, who therefore have no access to a European Union Digital Covid Certificate (EUDCC), will be granted access upon providing the same written proof they used to enter Germany, which should be a verifiable proof of vaccination / recovery that meets the validity requirements in Germany (please see previous questions).

Please see the list of non-EU countries (and territories) that have joined the EU Digital COVID Certificate system. 

Please note that Baden-Württemberg state accepts only digitally verifiable proof for the 2G rule such as a QR code. The primary means of verifying COVID vaccination status in Germany is through the “EU Digital Covid Certificate”. This can be obtained from the local pharmacies by showing them your vaccination papers together with an ID document. The pharmacy will give you the printouts which you can then enter into a mobile application ( Corona-Warn-App).

Where can I get a COVID-19 test in Heidelberg?

It is not possible to get a COVID-19 test while on site at EMBL. Professional testing stations are readily accessible at many convenient locations throughout Heidelberg. Additionally, many testing tents are available throughout the city.  

These testing stations offer lateral flow antigen tests that are free of charge, and on a ‘walk-up’ or appointment basis for all, including visitors. Results and certificate are sent by email, within approximately 20 minutes. Please note, some testing stations offer PCR tests as well, however these require a fee and is to be paid by the participant. 

If you are staying at the ISG Hotel, the closest testing station is located on the parking lot in front of the hotel. Another one can be found at Louise-Ebert-Zentrum (just 2 minutes walk or 150m from the ISG Hotel).

What are the current local restrictions (e.g. public transport, restaurants or cafes)?

Local restrictions change depending on the current pandemic situation. Before entering a building, you should be able to see signs with admittance rules that will mention 2G or 3G.

• 2G rule means that only vaccinated or recovered people are allowed to enter

• 3G rule includes fully vaccinated, recovered or tested

A negative rapid antigen test not older than 24 h or PCR test not older than 48 h is required as a test. Please bring your CovidPass and ID wherever you go and make sure to have enough FFP2 masks. Additionally please find here the current local Public transportation requirements (in German).

Where can I find more information?

Information on the COVID measures and travel restrictions in place in European countries can be found on the following websites: https://www.auswaertiges-amt.de/en/coronavirus/2317268 and https://reopen.europa.eu/en. These websites also contain information on what personal information and documents you will need to have with you to travel.

Please find additional information including FAQs, terms and conditions, COVID-19 safety policy and travelling to EMBL on our Information for Participants page.