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Brain (epi)genome – Course and Conference Office

EMBO Workshop

Brain (epi)genome

Overview

This conference will take place at EMBL Heidelberg, with the option to attend virtually.

Conference overview

The brain’s remarkable cellular diversity — encompassing hundreds of distinct neuronal and glial cell types — emerges from a single genome through sophisticated regulatory mechanisms. This EMBO Workshop brings together leaders in genomics, neuroscience, and epigenetics to advance our understanding of how the (epi)genome achieves this diversity, shaping brain function and behaviour.

Recent technological breakthroughs in single-cell, spatial, and 3D genomics and epigenomics are revealing unprecedented insights into the molecular logic behind neural diversity as well as neuronal connectivity and function. But there is much we do not understand, especially when trying to link these molecular and cellular processes to higher brain functions such as memory and behavior, or to disrupted brain states in aging and disease. Progress in these directions will require studies in human cells with traditional and emerging model organisms, all of which will be featured in this workshop.

Key questions at the cutting edge of the field will be explored, such as: how does three-dimensional chromatin architecture orchestrate cell-type-specific gene expression? What (epi)genomic processes govern the establishment and maintenance of neuronal identity and connectivity? How do activity-dependent changes in transcription and chromatin contribute to synaptic plasticity and memory? How might the dysregulation of these processes underlie neurodevelopmental and neurological disorders?

By bridging genomics, neuroscience, and epigenetics, this conference aims to stimulate new ideas on how the (epi)genome orchestrates brain function and to solidify the growing scientific community that sees the intersection of these three disciplines as fundamental to our understanding of the brain.

Session topics

  • Epigenetic basis of neural diversity
  • Chromatin and neurodevelopment
  • Gene regulation in stress and memory
  • (Epi)genomics of brain plasticity and behaviour
  • Ageing and neurological disorders
  • Single-cell, spatial, and 3D genomics in the brain

Speakers

Mareike Albert

TU Dresden

Germany

Andrea Brand

Gurdon Institute, University of Cambridge

UK

Anne Brunet

Stanford University

USA

Daniele Canzio

University of California San Francisco, San Francisco

USA

Gonçalo Castelo-Branco

Karolinska Institute

Sweden

Zoe Donaldson

University of Colorado Boulder

USA

Joseph Ecker

Salk Institute

USA

Maria Cristina Gambetta

University of Lausanne

Switzerland

Jarrett Grayson Camp

University of Basel

Switzerland

Oliver Hobert

Columbia University

USA

Tae-Kyung Kim

Pohang University of Science and Technology

South Korea

Erica Korb

University of Pennsylvania

USA

Jelena Radulovic

Aarhus University

Denmark

Filippo M. Rijli

Friedrich Miescher Institute for Biomedical Research

Switzerland

Anne Schäfer

Max Planck Institute for Biology of Ageing

Germany

Tomohisa Toda

FAU Erlangen & Max-Planck-Zentrum für Physik und Medizin

Germany

Yang Shi

University of Oxford

UK

Scientific organisers

Mathieu Boulard

EMBL Rome

Italy

Roberto Bonasio

University of Pennsylvania

USA

Kyung Min Noh

Aarhus University

Denmark

Anne Schäfer

Max Planck Institute for Biology of Ageing

Germany

Preliminary programme

Are you on social media? Post using #EMBOBrainEpi and don’t forget to tag @EMBLEvents.

  • Please note that the programme is subject to change. Some speakers may need to join virtually to give their talk
  • For registered participants, recorded talks will be accessible on demand for 4 weeks after the end of the event, unless indicated otherwise
Day 1: Tuesday, 21 April 2026
Time (Europe / Berlin)Session
13:00 – 14:30Registration
14:30 – 14:45Opening remarks
15:00 – 17:45Session 1: Epigenetic basis of neural diversity
15:00 – 15:25Single cell 3D multi-omics in the brain
Joe Ecker – Salk Institute, USA
15:25 – 15:40Selected short talk #1
15:40 – 16:05Role of cell surface diversity in neural
circuit assembly

Daniele Canzio – University of California, San Francisco, USA
16:05 – 16:20Selected short talk #2
16:20 – 16:50Coffee Break and Meet the Speakers of the session
16:50 – 17:15The operational principles of neuron-microglia circuits
Anne Schaefer – Max Planck Institute for Biology of Ageing, Germany
17:15 – 17:30Selected short talk #3
17:30 – 17:45Selected short talk #4
17:45 – 18:45Poster sneak peek
18:45 – 20:15Dinner in Canteen
20:15 – 21:45After dinner drinks
Day 2: Wednesday, 22 April 2026
Time (Europe / Berlin)Session
09:00 – 11:45Session 2: Chromatin and neurodevelopment
09:00 – 09:25Epigenetic mechanisms governing neural stem cell reactivation and differentiation
Andrea Brand – Gurdon Institute, University of Cambridge, UK
09:25 – 09:40Selected short talk #5
09:40 – 09:55Selected short talk #6
09:55 – 10:25Coffee Break and Meet the Speakers of the session
10:25 – 10:50Epigenetic regulation of neurodevelopment
Filippo M.Rijli – Friedrich Miescher Institute for Biomedical Research, Switzerland
10:50 – 11:05Selected short talk #7
11:05 – 11:30Transcription factors in neurodevelopment
Oliver Hobert – Columbia University, USA
11:30 – 11:45Selected short talk #8
11:45 – 13:15Vegetarian Lunch and Meet the Editors
13:15 – 16:05Session 3: Gene regulation in stress and memory
13:15 – 13:40Enhancer RNAs in brain function
Tae-Kyung Kim – Pohang University of Science and Technology, South Korea
13:40 – 13:55Selected short talk #9
13:55 – 14:10Selected short talk #10
14:10 – 14:40Coffee Break and Meet the Speakers of the session
14:40 – 15:05Maintenance of memory representations
through neuron-specific immune pathways

Jelena Radulovic – Aarhus University, Denmark
15:05 – 15:20Selected short talk #11
15:20 – 15:35Selected short talk #12
15:35 – 16:05Flash talk session 1
16:05 – 17:35Poster Session 1 (odd number)
17:35Free evening
Day 3: Thursday, 23 April 2026
Time (Europe / Berlin)Session
09:00-11:50Session 4: (Epi)genomics of brain plasticity and behavior
09:00 – 09:25Histone marks and variants in neuronal
function

Erica Korb – University of Pennsylvania, USA
09:25 – 09:40Selected short talk #13
09:40 – 09:55Selected short talk #14
09:55 – 10:25Coffee Break and Meet the Speakers of the session
10:25 – 10:50Neurobiological and genetic mechanisms of social bonding
Zoe Donaldson – University of Colorado Boulder, USA
10:50 – 11:05Selected short talk #15
11:05 – 11:30Evolutionary expansion of the neocortex
Mareike Albert – TU Dresden, Germany
11:30 – 11:45Selected short talk #16
11:45 – 13:15Lunch
13:15 – 16:00Session 5: Ageing and neurological disorders
13:15 – 13:40Chromatin and RNA modifi cations in brain
disease

Yang Shi – University of Oxford, UK
13:40 – 13:55Selected short talk #17
13:55 – 14:10Selected short talk #18
14:10 – 14:40Coffee Break and Meet the Speakers of the session
14:40 – 15:05Ageing consequence on maintenance of
neural identity

Tomohisa Toda – DZNE Dresden, Germany
15:05 – 15:20Selected short talk #19
15:20 – 15:45Epigenomics of brain ageing
Anne Brunet – Stanford University, USA
15:45 – 16:00Selected short talk #20
16:00 – 16:30Flash Talks Session 2
16:30 – 18:00Poster Session 2 (even numbers)
18:00 – 19:30Dinner
19:30 – 23:00Conference party
Day 4: Friday, 24 April 2026
Time (Europe / Berlin)Session
09:00 – 12:00Session 6: Single-cell, spatial, and 3D genomics in the brain
09:00 – 09:25Long-range gene regulation in neurons
Maria Cristina Gambetta – University of Lausanne, Switzerland
09:25 – 09:40Selected short talk #21
09:40 – 10:05Exploring neural organoid phenotypic spaces
Jarrett Grayson Camp – University of Basel
10:05 – 10:35Coffee Break and Meet the speakers
10:35 – 10:50Selected short talk #22
10:50 – 11:05Selected short talk #23
11:05 – 11:20Selected short talk #24
11:20 – 11:45Single-cell and spatial epigenomics of oligodendrocyte lineage cells in multiple sclerosis
Gonçalo Castelo-Branco – Karolinska Institute, Sweden
11:45 – 12:00Closing remarks and poster prize announcements
12:00Packed lunch and departure

Practical information

Registration fees

On-site registration fees

Your registration for the on-site event includes:

  • Admission to the event
  • Possibility to submit an abstract
  • Meals and coffee breaks
  • Conference materials
  • Access to the online event platform
  • Access to all livestreamed talks
  • Video library of the recorded talks during the event and for four weeks afterwards. Please note: at the request of individual speakers, some talks are not recorded.
  • A letter to support your visa application (for more information, check the ‘Travel and accommodation’ tab)

Accommodation and travel are not included in the fees. Participants are expected to book and pay their own expenses.

On-site Academia€500
On-site PhD Student€385
On-site Industry€770
On-site Journal Editors*€300

* Editors from scientific journals are allowed to attend at a reduced rate, but asked to contribute to the conference in return by taking part in ‘meet the editors’ sessions or other planned activities within the programme.

Virtual registration fees

Your virtual registration for the event includes:

  • Access to the online event platform
  • Access to all the livestreamed talks
  • Opportunity to submit questions
  • Video library of the recorded talks during the event and for four weeks afterwards.
    Please note: at the request of individual speakers, some talks are not recorded.

Virtual Academia€200
Virtual PhD Student€150
Virtual Industry€275

Note: accredited journalists may be eligible to register for complimentary on-site or virtual press registration. Registrants may be required to provide accreditation or equivalent proof of press membership after registration. Please contact Adéla Graf for more information.

Confirmation and payment

Registration will be on a first come, first served basis. Your place can only be confirmed after payment of the registration fee. If you are added to our waiting list, please consider taking advantage of our offerings to participate virtually.

On-site participants: types of payments accepted are international bank transfers and credit card payments. 

Virtual participants: we are only able to accept card payments. In exceptional cases we can accept bank transfers. Please contact events@embl.de for details.

Cancellation policy

If you are no longer able to take part in the conference, please inform your conference contact responsible for this event. Your registration and the submitted abstract will be deleted.

Please also check our Terms and Conditions for the cancellation policy.

Abstract submission

Abstract submission

Only participants registering to attend the on-site event are eligible to submit an abstract. Unfortunately, abstracts will not be accepted from virtual participants.

After registration you can submit your abstract via a separate link that will be provided in the email confirmation. Alternatively, you can access the link on the confirmation page directly after registering. The same login credentials are used for both processes.

Things to keep in mind when preparing the abstract:

Abstract body: The limit of 2,000 characters refers to manually typed text and excludes spaces. If an error occurs try using a different web browser (preferably Google Chrome or Mozilla Firefox).

If you copy-paste the text into the form, hidden formatting might still be included which may cause the text to exceed the 2,000 character limit resulting in an error message. We recommend you clear all formatting before pasting in the text.

If you have special symbols in your text, make sure you are using Unicode characters, otherwise these will not be recognised.

Title: The title should not exceed 20 words. Only the first word of the title should start with a capital letter and the rest should be lowercase.

Authors and affiliations: Please fill in the author’s details as requested in the online form. The compulsory fields are: First Name, Last Name, Organisation Name (Affiliation or Company), Country and Email.

Kindly mark only one author in the role of First Author and please don’t forget to indicate who will be the Presenter.

Please enter your co-authors correctly via the system by adding accounts together with their organisation/institute. Do not copy-paste them into the body of the abstract text, as they will not be indexed in the abstract book.

Presentation types: When submitting your abstract, you can apply for an oral or poster presentation. A selection process will take place with the results announced 2-3 weeks after the abstract submission deadline.

For detailed instructions on how to submit a conference abstract, follow the instructions provided in this video.

Please check our FAQs pages for further information on how to submit an abstract.

Financial assistance

Financial assistance

Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of travel grants and childcare grants.

Your place in the meeting is only confirmed by paying the registration fee, which is mandatory even when receiving a travel grant / fee waiver.

Travel grant

The travel grant will cover the cost of travel to an on-site event (airfare, train, bus, taxi, accommodation, visa) and/or registration fees and is provided up to specified caps which are normally as follows:

– up to €500 for any participant travelling to an EMBO Workshop.

– up to €1000 for any participant working in Chile, India, Singapore or Taiwan travelling to an EMBO Workshop.

The organisers may reduce the grant cap to accommodate more participants. Recipients will be notified of their travel cap amount when they are informed of the outcome of their application. Original receipts must be provided with your signature for all costs incurred within two months of completion of travel. Scanned copies cannot be accepted.

Childcare grant

There is the possibility to apply for a childcare grant to offset child care costs incurred by participants, speakers, and organisers when attending a conference.

Eligible costs include (but are not limited to) fees for a baby-sitter or child-care facility, and travel costs for a caregiver. Please note that priority will be given to early stage researchers. In order to apply for this grant, you must be registered by the abstract submission deadline. There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants.

Application

On-site participants

You may apply for financial assistance when submitting your abstract. In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career. Application for financial support will not affect the outcome of your registration application.

Virtual participants

If you are attending virtually, you can apply for financial assistance in the submission portal by the abstract deadline. Read the instructions on how to apply for financial assistance. Only submissions for financial assistance will be accepted. Presentation abstracts cannot be submitted here and will be declined. 

In your application you will be asked to summarise your current work,  answer questions regarding why your lab cannot fund your attendance, and how your attendance will make a difference to your career. Application for financial support will not affect the outcome of your registration application.

Selection

The scientific organisers will select the recipients of registration fee waivers and travel grants during the motivation letter or abstract selection process. Results will be announced approximately 6 – 8 weeks before the event start date, however for some events this may be delayed. Selection results do not impact your admission to the meeting. Selection for registration fee waivers and travel grants is based on scientific merit, your current work or study location, the reasons for needing financial support, and the impact this event will have on your career.

Childcare grants will be allocated in the same timeframe (6-8 weeks before the event start date). Please note that priority will be given to early-stage researchers.

Reimbursement

Costs will be reimbursed after the meeting only once a reimbursement form and original receipts (from travel costs) have been received.

Further details

View our list of external funding opportunities or refer to the FAQ page.

Become an event reporter

At our conferences we also offer the option to become an event reporter. By attending the meeting, sharing your insights on social media, and writing a detailed report, you can offset the conference fees. Please read the instructions on how to apply.

Travel and accommodation

Visa

We can send you a registration confirmation to support your visa procedure (not an official invitation letter). Please contact the conference officer responsible for your event. For more information, please see here.

Travel

If you are travelling to Heidelberg via airplane, train, car or long-distance bus, you can find useful information here.

Accommodation

Accommodation is not included in the conference registration fee.

Invited speakers please be wary of fraudulent ‘hotel services’ contacting you to ask for payments, see our Accommodation Scam Alert for more information.

A list of hotels with rooms on hold will be announced here closer to the time. Please email the hotel directly, quoting the booking code BRG26-01 to confirm the exact price of the room.

Please note that as of 1 October 2025, Heidelberg City Council is introducing an overnight stay tax for tourists visiting Heidelberg (including work related trips). The cost will be 3.50 EUR per night for the first five nights of a consecutive stay and will be added to the hotel’s nightly rate. Please contact the individual hotel directly if you have any questions.

Local transportation

Conference shuttle buses

Conference shuttle buses are free of charge for participants, and depart from designated bus stops near the hotels to EMBL and back, mornings and evenings.

The bus stops for this conference are:

  • Staycity Aparthotel (Speyerer Str. 7)
  • Kurfürsten-Anlage (Opposite Main Train Station)
  • Premier Inn City Zentrum (Kurfürsten-Anlage 23)
  • Leonardo Hotel Heidelberg City Center (Bergheimer Str. 63)
  • Neckarmünzplatz (Heidelberg Tourist Information)
  • Peterskirche (Bus stop)
  • Hilton Hotel (Kurfürsten-Anlage 1)
  • ISG Hotel (Im Eichwald 19)

View Conference shuttle bus stops and hotels in a larger map. Please note that not every bus stop will be used for every event.

Other local transportation

In addition to the shuttle busses, there is also the public bus 28 that serves the EMBL campus and taxis can be easily booked at any time. For more information, see here.

Further details

Address: EMBL, Meyerhofstraße 1, 69117 Heidelberg, Germany.

For more information about accommodation and travel, please refer to the FAQ page.

On-site information

Here you will find useful information for when you are onsite at the event.

Catering

All meals and coffee breaks are included in the registration fee. Our catering staff will prepare a variety of vegetarian meals, meat and fish dishes, soups, pasta, fresh fruit and vegetables, as well as a variety of desserts.

Please wear your badge at all times when serving yourself.

No food or drinks are allowed in the auditorium.

Internet

Wi-Fi is available on campus using the EMBL-Events network and the event specific password, which will be provided on site. The eduroam network (secure, worldwide roaming access service developed for the international research and education community) is also available.

Photography

During the conference, an EMBL Photographer may be taking photos. If you would not like to appear in these, please inform the photographer or a member of the Course and Conference Office.

Charging stations

There are lockers available next to the stairs leading down into the Auditorium. You will find some of those equipped with sockets to charge your smartphone/tablet etc.

In most places the electricity is 220 volts AC (50 cycles). An adaptor and a plug that fits the German socket may be needed for your appliances/laptop (i.e. American, Japanese, etc.). A USB charging station for electronic devices is available at the registration desk.

Printing

We can help to print your boarding pass/train ticket. Please send it to events@embl.de and collect your print-outs at the registration desk.

Luggage

There are lockers available on-site to store your luggage, which require a 2 EURO coin to operate. There is another luggage room on level E0, which is free to use but remains unlocked during the conference.

Lost and found

‘’Lost and Found’’ items are kept at the registration desk until the end of the conference.

EMBL merchandise

If you are interested in purchasing EMBL merchandise (products presented in the glass display in the registration area), please email the EMBL shop to place an order.

Kindly note the EMBL shop is only open upon request and all purchases must be made in cash (Euros only).

Nursing room

There is a nursing room available in the ATC Rooftop Lounge on level A29.

Room for prayers, meditation, and yoga

There is a room for prayer, yoga, and meditation, located on level E0 behind the Auditorium. Please be respectful of others using the room.

EMBL campus map

Health and safety notes

Please take a moment to read our health and safety policy.

  • Do not smoke in any EMBL building.
  • Eating and drinking is prohibited in the Auditorium and all laboratories.
  • Do not enter any restricted areas or the laboratories unless instructed to do so.

If first aid is required

  • The first aid room is located next to the ATC Registration Desk (room 10- 205).
  • Dial the Emergency number 222 from any EMBL internal phone only.
  • Be prepared to answer the following questions: Where is the accident? What happened? How many injured?
  • Emergency number 06221-387 7821 from mobile phones.
  • Please report all accidents to the conference officer at the registration desk.

In case of fire

  • Press the nearest fire alarm button or the Emergency number 222 from any internal phone.
  • A loud fire alarm will go off if an evacuation is required. On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points
  • Do not use the lifts.

Beyond first aid

The Heidelberg University Hospital or ‘Universitätsklinikum‘ has a 24 hour accident and emergency facility and is at ‘Im Neuenheimer Feld 672’. It is a 8km or a 20 minute taxi ride away from EMBL. In a medical emergency, the ambulance service generally transports patients to this hospital.

Please remember to bring your own medication, if needed, to the conference. Note that the next pharmacy is a 4-minute drive from the EMBL, but for many medications you will be required to see a doctor to get a prescription.

Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg.

The EMBL course and conference office team are able to advise you on where to turn for emergency or non-emergency medical treatment in Heidelberg and can assist you in making appointments and / or arranging transport to get to the pharmacy or a doctor of your choice if necessary. Please note, we are not however permitted to personally accompany you off-campus.

Sightseeing

A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing.

Event platform

Access

Access to the event platform is given to all on-site and virtual participants.

You can use the event platform to:

  • Access to all the livestreamed talks
  • Opportunity to submit questions (for virtual participants)
  • Video library of the recorded talks during the event and for four weeks afterwards. Please note: at the request of individual speakers, some talks are not recorded
  • Access to the abstract book
  • Opportunity to engage with speakers and other participants via the discussion area and chat functionality
  • Other useful information (How to give a good scientific talk, or to make a good scientific poster, and more)

More information about the platform will be shared ahead of the conference.

Guidelines

  • Please do not share the link to the course or conference platform with anyone else
  • Do not broadcast the conference to unregistered participants.
  • You are encouraged to post about the event. Post unless the speaker specifically says otherwise, but be mindful of unpublished data. 
  • Please do not capture, transmit or redistribute data presented at the meeting.

Additional information can be found in our Code of Conduct.

Time zone

The programme is planned based on the Europe/Berlin time zone, unless otherwise stated. Please take your time zone into consideration when planning your attendance.

Additional information

Please find additional information including FAQs, terms and conditions, and travelling to EMBL on our Information for participants page.

Sponsors

Sponsorship opportunities

We offer a variety of event sponsoring possibilities, with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget. Discounts are available for companies sponsoring multiple events at EMBL Heidelberg. View other conferences, or contact sponsorship@embl.org for further information on sponsoring possibilities.

If you are interested in becoming a media partner of this event, please visit our media partnerships webpage.

Warning

EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials. One current scam campaign of which we are aware is conducted using the name ‘Judy Eastman’ (judy@gopcontact.a2hosted.com) and entails approaches to sponsors offering sponsorship opportunities on EMBL’s behalf. Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences, symposia and courses is handled by EMBL directly and is sent from an official EMBL account. EMBL does not work with any external providers on sponsorship acquisition.

Please also note that:

  • EMBL never provides attendee lists for purchase. Any offers of such are fraudulent.
  • EMBL will never call or email you to ask for your credit card details or to request a payment.
  • All payments are on invoice.

Suspicious communications purportedly from, for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship@embl.de.

Date: 21 - 24 Apr 2026

Location: EMBL Heidelberg and Virtual

Venue: EMBL Advanced Training Centre


Deadline(s):

Registration (On-site): 10 Mar 2026

Registration (Virtual): 14 Apr 2026


Organisers:

  • Roberto Bonasio
    University of Pennsylvania, USA

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