New EU-funded Project: Fragment-Screen
Lab Matters EMBL is one of the partners of this project that aims to accelerate drug discovery and development, bringing in expertise from EMBL Grenoble and EMBL-EBI.
2023
lab-matters
Getting closer to stopping toxoplasmosis infection
Science Recent studies supported by EMBL Grenoble’s expertise in structural biology research and scientific services have identified Altiratinib as a potential drug to stop toxoplasmosis infection and opened up treatment options against malaria.
2022
science
Molecular solar panels can help scientists control brain cells
EMBLetc Kirill Kovalev, an EMBL Hamburg researcher, is studying the structure of an ancient bacterial molecule to help scientists control brain cell activity
2022
Two in one: combining MASSIF-1 and CrystalDirect
Lab Matters Researchers and engineers have integrated a CrystalDirect harvester into the fully automated beamline MASSIF-1, a unique combination of structural biology technologies that is now open to external academic users.
2022
lab-matters
MASSIF-1 beamline in Grenoble supports COVID-19 drug discovery
Lab Matters MASSIF-1, run jointly by EMBL Grenoble and the ESRF, is a beamline for macromolecular crystallography. It is used by the research community to study the 3D structure of proteins, which is important for drug development.
2021
lab-matters
Shaping the future of structural biology and X-ray imaging at EMBL Hamburg
Events A workshop run by EMBL Hamburg explored opportunities for structural biology at the future, upgraded PETRA IV synchrotron.
2021
events
Structural biology at EMBL: driving technology development
Lab Matters Florent Cipriani, who recently retired as Head of the Instrumentation Team after a long career at EMBL Grenoble, is one of the pioneers of instrumentation development in this field.
2021
lab-matters
New perspectives for treating psychiatric disorders
Science Scientists have determined the structure of Glycine Transporter 1. The finding could open new avenues for developing therapeutics for psychiatric disorders
2021
science
Droplet beauty
Picture of the week Scientists at EMBL Hamburg use droplets of protein solution to grow protein crystals. By exposing the crystals to X-rays, they are able to determine the protein’s molecular structure.
2021
picture-of-the-week
Upgraded beamlines at EMBL Grenoble unveiled
Science The beamlines run jointly by EMBL Grenoble and the ESRF reopen today, unveiling significant upgrades that exploit the brand new fourth generation ESRF synchrotron source.
2020
science
Investigating the structure and mechanisms of coronavirus biomolecules
Science While global research on coronaviruses has shed light on the function of many SARS-CoV-2 proteins, the role of some crucial components remains unknown. Researchers at EMBL Grenoble will use a range of structural biology methods to try to solve some of the puzzles of the molecular mechanics of…
2020
science
Facilitating COVID-19 structural biology research
Science EMBL and the European Synchrotron Radiation Facility (ESRF) restart the activities of the Joint Structural Biology Group in Grenoble to support coronavirus-related projects. A new initiative will allow users to be granted access to the High-Throughput Crystallisation (HTX) lab at EMBL and to a…
2020
science
Responding to health threats posed by coronaviruses
Science By re-opening the High-Throughput Crystallisation (HTX) lab at EMBL Grenoble, EMBL is supporting structural biology projects to respond to the health threats posed by coronaviruses.
2020
science
Exploring synthetic antibodies to stop coronavirus
Science Scientists at EMBL Hamburg and Karolinska Institutet Stockholm aim to find synthetic antibodies – known as nanobodies – that bind a surface protein of the novel SARS-CoV-2 coronavirus. Nanobodies could prevent the virus from entering human cells and causing COVID-19.
2020
science
How to shoot the messenger
Science Cells rely on a range of signalling systems to communicate with each other and to control their own internal workings. Scientists from the European Molecular Biology Laboratory (EMBL) in Hamburg, Germany, have now found a way to hack into a vital communications system, raising the possibility of…
2010
science
Drought resistance explained
Science Much as adrenaline coursing through our veins drives our body’s reactions to stress, the plant hormone abscisic acid (ABA) is behind plants’ responses to stressful situations such as drought, but how it does so has been a mystery for years. Scientists at the European Molecular Biology…
2009
science
Raising the alarm when DNA goes bad
Science Our genome is constantly under attack from things like UV light and toxins, which can damage or even break DNA strands and ultimately lead to cancer and other diseases. Scientists have known for a long time that when DNA is damaged, a key enzyme sets off a cellular ‘alarm bell’ to alert the…
2009
science
The giant protein titin helps build muscles
Science Imagine grabbing two snakes by the tail so that they can’t wriggle off in opposite directions. Scientists at the Hamburg Outstation of the European Molecular Biology Laboratory (EMBL) and collaborators from King’s College in London have now discovered that something similar happens to a…
2006
science
A key that opens cells to the deadly malaria parasite
Science Researchers at the International Centre for Genetic Engineering and Biotechnology (ICGEB) in India and a unit of the European Molecular Biology Laboratory (EMBL) in France have made a key discovery about a molecule that helps the malaria parasite infect human cells. India is one of the countries…
2005
science
New high-throughput crystallization facility at EMBL Hamburg to give boost to structural biology community
Lab Matters Today the European Molecular Biology Laboratory (EMBL) opens a new highthroughput crystallization facility at its Outstation located on the campus of the German Synchrotron Radiation Facility (DESY) in Hamburg, Germany. The facility, made possible by major funds from the German Ministry for Science…
2005
lab-matters
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