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Forkhead-Ets cooperation

How transcription factors work together

EMBL researchers have developed a method to observe interactions between transcription factors…

By Fabian Oswald

Science

TF bound to DNA

A classification tool for transcription factors

The software diffTF quantifies activity of transcription factors and predicts their mode of action…

By Fabian Oswald

Science

mitf stammer

Understanding a key player in melanoma

A new paper describes a unique mechanism of partner selectivity in transcription factors.…

By Fabian Oswald

Science

Stripes of colour display gene expression patterns

Transcriptional hubs confer phenotypic robustness

Enhancers in Drosophila embryos gather together to preserve phenotypes under stressful conditions…

By Josh Tapley

Science

The pyramids represent chromatin domains in the wild-type situation. The reflection in the water below represents the rearrangements in the mutant fruit fly chromosomes. At first glance the (regulatory) landscapes look very similar, but there are lots of changes to the topology, and yet these have little impact on the nature of the landscape (gene expression). IMAGE: Beata Edyta Mierzwa in collaboration with EMBL.

Rearranging chromosomes

Does rearranging chromosomes affect their function? EMBL scientists reveal uncoupling of 3D chromatin organisation and gene expression.…

By Iris Kruijen

Science

How cellular signalling controls chromatin modification. IMAGE: Aleksandra Krolik/EMBL

Transcription factors controlled by DNA sequence

EMBL scientists gain mechanistic insights into how cellular signalling controls gene regulation…

By Patrick Mueller

Science

DNA replication stress in cancer

Thanos Halazonetis discusses the EMBO/EMBL Symposium: DNA Replication: From Basic Biology to Disease…

By Nicola Vegiopoulos

Events

Wojciech Galej, new group leader at EMBL

Welcome: Wojciech Galej

New group leader Wojciech Galej investigates RNA-protein complexes involved in gene expression…

By Margaux Phares

Science

To train T-cells to recognise our own body, cells in the thymus express different combinations of 'extra' genes. IMAGE: EMBL/P.RIEDINGER

Know your cells

How T-cells are trained on what not to kill…

By Sonia Furtado Neves

Science

Judith Zaugg. PHOTO: EMBL/M. SCHUPP

Welcome: Judith Zaugg

Whether it’s information or people, the art of connecting is key to new group leader Judith Zaugg…

By Sonia Furtado Neves

Science

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