genome
The curious genome of the tuatara, an ancient reptile in peril
A global team of researchers including the Flicek Team at EMBL-EBI has partnered up with the Māori tribe Ngātiwai to sequence the genome of the tuatara, a rare reptile endemic to New Zealand.
Bagpipe and Pokemon, or how not to name a human gene
The human genome harbours about 19 000 protein-coding genes, many of which still have no known function. As scientists unveil the secrets of our DNA, they come across novel genes that they need to refer to using a unique name. The Human Genome Organisation’s Gene Nomenclature Committee (HGNC) at…
EMBL boosts national and international sharing of genomic data
A national consortium including EMBL and the DKFZ is set to launch the German Human Genome–Phenome Archive, creating an invaluable bridge between fundamental biomedical research and applied healthcare.
The Pan-Cancer project
EMBL co-leads most comprehensive study of genetic causes of cancer
Protecting data in the cloud
Cloud computing offers unprecedented opportunities for global-scale research collaborations. It also presents a unique set of challenges in terms of data protection and the ethics of data sharing.
Characterising RNA alterations in cancer
The largest and most comprehensive catalogue of cancer-specific RNA alterations reveals new insights into the cancer genome.
Cancer mutations occur decades before diagnosis
Researchers at EMBL’s European Bioinformatics Institute (EMBL-EBI) and the Francis Crick Institute have analysed the whole genomes of over 2600 tumours from 38 different cancer types to determine the chronology of genomic changes during cancer development.
Studying DNA rearrangement to understand cancer
Using the dataset from the Pan-Cancer project, scientists has developed methods to group, classify, and describe large rearrangements of the genome that are a key driver of cancer.
Scientists identify new genetic drivers of cancer
Analysis of whole cancer genomes gives key insights into the role of the non-coding genome in cancer
Chromothripsis in human cancer
Researchers at Harvard Medical School and EMBL-EBI have carried out the largest analysis across cancer types of the newly discovered mutational phenomenon chromothripsis.
