15 November 2023
Promiscuity is critical for nourishment. How? This question lies at the focus of research by the Löw Group at EMBL Hamburg. Using structural biology methods, they explore how specialised molecules located in the cell membrane allow cells absorb nutrients from their environment.
17 October 2023
In an extensive investigation, EMBL researchers have tested over 10,000 drug combinations against some of the leading pathogenic bacteria carrying antimicrobial resistance and causing mortality.
26 September 2022
Researchers have come up with a way to test the efficacy of hundreds of anticancer drug combinations – simultaneously, rapidly, and accurately.
8 December 2021
Researchers studying a massive cohort of European patients have found that commonly prescribed drugs for cardiometabolic disorders can have long-term effects on the gut microbiome. Such effects can complicate the understanding of how disease affects the microbiome and must be taken into…
3 November 2021
Scientists at EMBL Hamburg determined the molecular structure of Peptide Transporters 1 and 2. The findings will enable developing drugs that more efficiently pass from the gut to target tissues.
8 September 2021
A new collaborative study led by EMBL group leaders Kiran Patil, Nassos Typas, and Peer Bork has found that common medications accumulate in human gut bacteria. This process reduces drug effectiveness and affects the metabolism of common gut microbes, thereby altering the gut microbiome.
9 February 2021
Researchers at EMBL Heidelberg have identified sequences in human proteins that might be used by SARS-CoV-2 to infect cells. They have discovered that the virus might hijack certain cellular processes, and they discuss potentially relevant drugs for treating COVID-19.
29 September 2020
Picture of the week
To study the effect of commonly used drugs on bacterial envelopes, EMBL scientists applied a biochemical assay using a colour reaction. The deeper the red, the stronger the disruptive effect of the drug.
8 September 2020
Researchers have found the cause of dilated cardiomyopathy – a leading cause of heart failure – and identified a potential treatment for it: a drug already used to treat acne.
1 July 2020
Open Targets welcomes new Informatics Science Director
15 April 2020
EMBL researchers are studying how drugs that have shown good results against COVID-19 work in living cells
20 January 2020
EMBL scientists identify drug targets in blood and organs
3 June 2019
Snapshots of the flu virus replication machine in action
11 March 2019
Scientists develop technology to measure how ATP concentration affects protein solubility in cells
23 January 2019
New director drives drug discovery partnership forward
6 July 2018
EMBL scientists investigate how bacteria melt to study their reaction to drugs
4 July 2018
Combining antibiotics with each other, non-antibiotic drugs or food additives can alter their effectiveness
22 June 2018
Combinations of cancer drugs can be quickly and cheaply tested using a novel microfluidic device
19 March 2018
One in four drugs with human targets inhibit the growth of bacteria in the human gut, and may promote antibiotic resistance, EMBL researchers report in Nature
11 August 2013
Like a fireman who becomes an arsonist, a protein that prevents cells becoming cancerous can also cause tumours, scientists at the European Molecular Biology Laboratory (EMBL) in Grenoble, France, have discovered. The finding, published today in Nature Structural and Molecular Biology, stems…
21 June 2012
Savira pharmaceuticals GmbH, a spin-off of the European Molecular Biology Laboratory (EMBL) based in Vienna, Austria, has signed a collaboration and license agreement with Roche, thus further strengthening the links between fundamental research and major pharmaceutical development companies. This…
11 July 2008
Researchers from the European Molecular Biology Laboratory (EMBL) discovered a new way to make use of drugs’ unwanted side effects. They developed a computational method that compares how similar the side effects of different drugs are and predicts how likely the drugs act on the same target…
11 February 2007
We all know that iron deficiencies are dangerous, but also too much iron is bad for our health. Our body stores excess iron in various tissues, where it can lead to organ failure and even death if not treated before irreversible damage has occurred. Researchers from the Innsbruck Medical…
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