Combi-seq: a leap forward for personalised cancer therapy
Science Researchers have come up with a way to test the efficacy of hundreds of anticancer drug combinations – simultaneously, rapidly, and accurately.
2022
science
The impact of drugs on gut microbes is greater than we thought
Science Researchers studying a massive cohort of European patients have found that commonly prescribed drugs for cardiometabolic disorders can have long-term effects on the gut microbiome. Such effects can complicate the understanding of how disease affects the microbiome and must be taken into…
2021
science
Structure of a promiscuous protein will help scientists design better drugs
Science Scientists at EMBL Hamburg determined the molecular structure of Peptide Transporters 1 and 2. The findings will enable developing drugs that more efficiently pass from the gut to target tissues.
2021
science
Common medications accumulate in gut bacteria
Science A new collaborative study led by EMBL group leaders Kiran Patil, Nassos Typas, and Peer Bork has found that common medications accumulate in human gut bacteria. This process reduces drug effectiveness and affects the metabolism of common gut microbes, thereby altering the gut microbiome.
2021
science
Protein sequences provide clues to how SARS-CoV-2 infects cells
Science Researchers at EMBL Heidelberg have identified sequences in human proteins that might be used by SARS-CoV-2 to infect cells. They have discovered that the virus might hijack certain cellular processes, and they discuss potentially relevant drugs for treating COVID-19.
2021
science
Colourful test tubes
Picture of the week To study the effect of commonly used drugs on bacterial envelopes, EMBL scientists applied a biochemical assay using a colour reaction. The deeper the red, the stronger the disruptive effect of the drug.
2020
picture-of-the-week
Fighting cardiovascular disease with acne drug
Science Researchers have found the cause of dilated cardiomyopathy – a leading cause of heart failure – and identified a potential treatment for it: a drug already used to treat acne.
2020
science
Welcome: Ellie McDonagh
Lab Matters Open Targets welcomes new Informatics Science Director
2020
lab-matters
Identifying how potential COVID-19 drugs work
Science EMBL researchers are studying how drugs that have shown good results against COVID-19 work in living cells
2020
science
Melting reveals drug targets in a living organism
Science EMBL scientists identify drug targets in blood and organs
2020
science
Paving the way for new flu drugs
Science Snapshots of the flu virus replication machine in action
2019
science
ATP affects proteome-wide solubility
Science Scientists develop technology to measure how ATP concentration affects protein solubility in cells
2019
science
New Open Targets Director appointed
Lab Matters New director drives drug discovery partnership forward
2019
lab-matters
Melting bacteria to decipher antibiotic resistance
Science EMBL scientists investigate how bacteria melt to study their reaction to drugs
2018
science
Combining antibiotics changes their effectiveness
Science Combining antibiotics with each other, non-antibiotic drugs or food additives can alter their effectiveness
2018
science
Miniature testing of drug pairs on tumour biopsies
Science Combinations of cancer drugs can be quickly and cheaply tested using a novel microfluidic device
2018
science
Commonly used drugs affect our gut bacteria
Science One in four drugs with human targets inhibit the growth of bacteria in the human gut, and may promote antibiotic resistance, EMBL researchers report in Nature
2018
science
From fireman to arsonist
Science Like a fireman who becomes an arsonist, a protein that prevents cells becoming cancerous can also cause tumours, scientists at the European Molecular Biology Laboratory (EMBL) in Grenoble, France, have discovered. The finding, published today in Nature Structural and Molecular Biology, stems…
2013
science
Flu fighters
Science Savira pharmaceuticals GmbH, a spin-off of the European Molecular Biology Laboratory (EMBL) based in Vienna, Austria, has signed a collaboration and license agreement with Roche, thus further strengthening the links between fundamental research and major pharmaceutical development companies. This…
2012
science
Teaching old drugs new tricks
Science Researchers from the European Molecular Biology Laboratory (EMBL) discovered a new way to make use of drugs’ unwanted side effects. They developed a computational method that compares how similar the side effects of different drugs are and predicts how likely the drugs act on the same target…
2008
science
Putting an old drug to a new use
Science We all know that iron deficiencies are dangerous, but also too much iron is bad for our health. Our body stores excess iron in various tissues, where it can lead to organ failure and even death if not treated before irreversible damage has occurred. Researchers from the Innsbruck Medical…
2007
science
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