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beamline

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19 December 2023 Cartoon showing nanoparticles on a conveyer belt passing through a machine. They are ordered by size and the smallest one pass through the machine before the bigger ones. A ray of light enters the machine, where a nanoparticle is being scanned, and leaves it on the other side. A monitor on top of the scanning machine shows an X-ray of a nanoparticle.

‘X-ray vision’ for investigation of mRNA nanomedicines

Science EMBL Hamburg, Johannes Gutenberg University Mainz, Postnova Analytics GmbH, and BioNTech SE have developed a new method to quantitatively investigate sizes of nanoparticles containing mRNA. It may become an important part of regular characterisation of mRNA nanomedicines in the future.

2023

science

2 October 2023 Outline of a human, purple against red background. Red RNA strand in the background, electrocardiogram across the image. On the right, outline of a Nobel prize medal.

mRNA nanomedicines scoop Nobel Prize in Physiology or Medicine

Science Pioneers of the mRNA nanomedicines technology receive 2023 Nobel Prize in Physiology or medicine. EMBL is pleased to have supported the development of the application of the mRNA nanomedicine technology through our long-standing collaboration with BioNTech, Johannes Gutenberg University Mainz and…

2023

science

6 September 2023 A drawing of swordfish and a bubble containing a drawing of a molecular model. Both on blue background representing water.

Swordfish sword under X-rays: SAXS explained

Science Learn how scientists use bio-SAXS, an experimental X-ray technique, to study the shape and dynamics of proteins and other biomolecules. SAXS can be even used to analyse the structure of mineral particles in the swordfish sword bone, which can help scientists better understand bone ageing.

2023

science

8 August 2023 Clément Blanchet at the EMBL Hamburg’s P12 beamline’s experimental hutch.

Welcome: Clément Blanchet

Lab Matters Clément Blanchet has been appointed to lead the team working on small-angle X-ray scattering (SAXS) at EMBL Hamburg. In this interview, he talks his ambitions for the future work of the SAXS Team, his passion for science, and a memorable ‘aha’ moment he had in his early career.

2023

lab-matters

15 May 2023 Two scientists in a laboratory

Behind the scenes of innovation

EMBLetc EMBL Grenoble technology teams provide a sneak peek into their latest collaborative project in structural biology services: the complete automation of an integral step in X-ray crystallography.

2023

17 March 2023 Liz Duke standing on the left side of the photo, with EMBL Hamburg's P14 beamline and a big screen on the right.

Molecules to Ecosystems: Liz Duke on X-ray imaging

Lab Matters Biological X-ray imaging is an emerging technology that uses X-rays to image tissues or even entire organisms. It will play an important role in EMBL Hamburg’s future service portfolio, and will allow studying life on multiple scales. Team Leader Liz Duke discusses her plans to establish X-ray…

2023

lab-matters

1 March 2023 Moisés Bueno is standing next to the transfer robot. The robot has a form of a yellow robotic arm on a stand. Behind is the CrystalDirect™ Harvester, which is a white cuboid with two transparent dimmed windows for laser protection.

Biology meets engineering

Lab Matters Physicists, engineers and robotics experts work together in EMBL Hamburg’s Instrumentation Team to design instruments that support structural biology research. The team has finished a transfer robot that facilitates automated handling of protein crystals with care and precision. This will help…

2023

lab-matters

1 December 2022

Getting closer to stopping toxoplasmosis infection

Science Recent studies supported by EMBL Grenoble’s expertise in structural biology research and scientific services have identified Altiratinib as a potential drug to stop toxoplasmosis infection and opened up treatment options against malaria.

2022

science

3 November 2022 View from above of a small room with several tools, cables and pieces of technology. A rectangular box, a robotic arm and a device are highlighted in green.

Two in one: combining MASSIF-1 and CrystalDirect

Lab Matters Researchers and engineers have integrated a CrystalDirect harvester into the fully automated beamline MASSIF-1, a unique combination of structural biology technologies that is now open to external academic users.

2022

lab-matters

7 December 2021 A cartoon image showing a person's arm and a needle with a vaccine being injected into it. The text on the left reads: "EMBL research: How structural biologists at EMBL Hamburg help to develop and improve RNA vaccines"

How structural biology helps to make RNA vaccines

Science RNA vaccines, such as the ones for COVID-19, represent a new approach in vaccine technology. Cy Jeffries, faculty staff scientist at EMBL Hamburg, explains the clever technology behind RNA vaccines, and how structural biology contributes to its development. EMBL Hamburg collaborated on several…

2021

science

5 November 2021 A headshot photo of Ken Holmes from July 2021

Ken Holmes

Alumni Ken Holmes, outstanding pioneer of structural biology and founder of EMBL´s Hamburg site, died on 2 November 2021 at the age of 87.

2021

alumni

15 October 2021 In the middle, there are two molecules of pUL21. One is blurred, to represent the molecule’s flexibility. In the background are two neuronal scenes. The one on the left is healthy and has a smooth surface. The one on the right is infected, which is represented by several green viral particles.

How herpes seizes proteins’ means of production

Science The Graham and Crump groups at the University of Cambridge and the Svergun Group at EMBL Hamburg have discovered a mechanism by which the herpes simplex virus takes control of the molecular machinery of human cells. Their work reveals how a dedicated viral protein hijacks key host proteins, forcing…

2021

science

13 July 2021 From right to left, Ilaria Piazza and Ken Holmes’ portraits are side by side in circles on a greenish background

EMBL Alumni Awards 2021

Alumni EMBL alumni Ilaria Piazza and Ken Holmes have been recognised for their outstanding contributions, and will receive their awards as part of the celebrations for EMBL World Alumni Day.

2021

alumni

26 January 2021 Two X-ray mirrors installed in the macromolecular crystallography beamline P14 at EMBL Hamburg. The mirrors are visible in the photo as dark rectangular crystal blocks, with two metal holders supporting the crystals in a stress-free position. The mirrors are inserted into a vacuum-compatible stainless steel vessel.

Mirror, mirror

Picture of the week Scientists at EMBL Hamburg use specially designed mirrors to reflect and focus X-ray beams onto tiny crystals made of proteins or other biological molecules.

2021

picture-of-the-week

9 June 2020 Beamline Hamburg

Shining high-brilliance beams on coronavirus structure

Science EMBL researchers are studying COVID-19-related molecules by exposing them to high-brilliance X-ray beams. The Svergun group at EMBL Hamburg is using biological small-angle X-ray scattering (SAXS) as part of a global effort by scientists to elucidate the structural organisation of SARS-CoV-2…

2020

science

8 November 2009

Drought resistance explained

Science Much as adrenaline coursing through our veins drives our body’s reactions to stress, the plant hormone abscisic acid (ABA) is behind plants’ responses to stressful situations such as drought, but how it does so has been a mystery for years. Scientists at the European Molecular Biology…

2009

science

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