Systems microbiology
Chemical genetic data of E. coli K12 (Keio deletion library & a transposon library) from different studies (Nichols et al. Cell 2011; Shiver et al. Plos Genetics 2016; Price et al. Nature 2018), and unpublished data from the Typas lab.
Fitness data in > 200 conditions, genomic sequence info and variant calling from a collection of ~ 700 E. coli strain natural isolates from Galardini et al. eLife 2017
Protein abundance and thermal stability data for ~ 1,800 proteins in 121 E. coli mutants – from Mateus et al. Nature 2020.
Drug combination data in thee Gram-positive species – from Cacace et al. Nature Microbiology 2023.
Drug cross-resistance and collateral sensitivity data in E. coli – from Sakenova et al. Nature Microbiol 2025.