Publications – Hackett Group

Maffei M, Morelli C, Graham E, Patriarca S, Donzelli L, Doleschall B, de Castro Reis F, Nocchi L, Chadick CH, Reymond L, Corrêa IR, Johnsson K, Hackett JA, Heppenstall PA

Scientific reports, 2019

doi:10.1038/s41598-019-55797-1.

Publisher Correction: Tracing the transitions from pluripotency to germ cell fate with CRISPR screening.

Hackett JA, Huang Y, Günesdogan U, Gretarsson KA, Kobayashi T, Surani MA

Nature communications, 2018

doi:10.1038/s41467-018-07765-y.

Tracing the transitions from pluripotency to germ cell fate with CRISPR screening.

Hackett JA, Huang Y, Günesdogan U, Gretarsson KA, Kobayashi T, Surani MA

Nature communications, 2018

doi:10.1038/s41467-018-06230-0.

Activation of Lineage Regulators and Transposable Elements across a Pluripotent Spectrum.

Hackett JA, Kobayashi T, Dietmann S, Surani MA

Stem cell reports, 2017

doi:10.1016/j.stemcr.2017.05.014.

STELLA modulates transcriptional and endogenous retrovirus programs during maternal-to-zygotic transition.

Huang Y, Kim JK, Do DV, Lee C, Penfold CA, Zylicz JJ, Marioni JC, Hackett JA, Surani MA

eLife, 2017

doi:10.7554/elife.22345.

Stella modulates transcriptional and endogenous retrovirus programs during maternal-to-zygotic transition.

Huang Y, Kim JK, Do DV, Lee C, Penfold CA, Zylicz JJ, Marioni JC, Hackett JA, Surani MA

ELIFE, 2017

doi:10.7554/eLife.22345.

A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development.

Tang WW, Dietmann S, Irie N, Leitch HG, Floros VI, Bradshaw CR, Hackett JA, Chinnery PF, Surani MA

Cell, 2015

doi:10.1016/j.cell.2015.04.053.

Chromatin dynamics and the role of G9a in gene regulation and enhancer silencing during early mouse development.

Zylicz JJ, Dietmann S, Günesdogan U, Hackett JA, Cougot D, Lee C, Surani MA

eLife, 2015

doi:10.7554/elife.09571.

PRMT5 protects genomic integrity during global DNA demethylation in primordial germ cells and preimplantation embryos.

Kim S, Günesdogan U, Zylicz JJ, Hackett JA, Cougot D, Bao S, Lee C, Dietmann S, Allen GE, Sengupta R, Surani MA

Molecular cell, 2014

doi:10.1016/j.molcel.2014.10.003.

Regulatory principles of pluripotency: from the ground state up.

Hackett JA, Surani MA

Cell stem cell, 2014

doi:10.1016/j.stem.2014.09.015.

Dynamic heterogeneity and DNA methylation in embryonic stem cells.

Singer ZS, Yong J, Tischler J, Hackett JA, Altinok A, Surani MA, Cai L, Elowitz MB

Molecular cell, 2014

doi:10.1016/j.molcel.2014.06.029.

Synergistic mechanisms of DNA demethylation during transition to ground-state pluripotency.

Hackett JA, Dietmann S, Murakami K, Down TA, Leitch HG, Surani MA

Stem cell reports, 2013

doi:10.1016/j.stemcr.2013.11.010.

Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation.

Grabole N, Tischler J, Hackett JA, Kim S, Tang F, Leitch HG, Magnúsdóttir E, Surani MA

EMBO reports, 2013

doi:10.1038/embor.2013.67.

Beyond DNA: programming and inheritance of parental methylomes.

Hackett JA, Surani MA

Cell, 2013

doi:10.1016/j.cell.2013.04.044.

Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine.

Hackett JA, Sengupta R, Zylicz JJ, Murakami K, Lee C, Down TA, Surani MA

Science (New York, N.Y.), 2013

doi:10.1126/science.1229277.

DNA methylation dynamics during the mammalian life cycle.

Hackett JA, Surani MA

Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2013

doi:10.1098/rstb.2011.0328.

Promoter DNA methylation couples genome-defence mechanisms to epigenetic reprogramming in the mouse germline.

Hackett JA, Reddington JP, Nestor CE, Dunican DS, Branco MR, Reichmann J, Reik W, Surani MA, Adams IR, Meehan RR

Development (Cambridge, England), 2012

doi:10.1242/dev.081661.

Parallel mechanisms of epigenetic reprogramming in the germline.

Hackett JA, Zylicz JJ, Surani MA

Trends in genetics : TIG, 2012

doi:10.1016/j.tig.2012.01.005.

Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome.

Thomson JP, Lempiäinen H, Hackett JA, Nestor CE, Müller A, Bolognani F, Oakeley EJ, Schübeler D, Terranova R, Reinhardt D, Moggs JG, Meehan RR

Genome biology, 2012

doi:10.1186/gb-2012-13-10-r93.

Apoptosis and DNA methylation.

Meng HX, Hackett JA, Nestor C, Dunican DS, Madej M, Reddington JP, Pennings S, Harrison DJ, Meehan RR

Cancers, 2011

doi:10.3390/cancers3021798.

The interaction of xKaiso with xTcf3: a revised model for integration of epigenetic and Wnt signalling pathways.

Ruzov A, Hackett JA, Prokhortchouk A, Reddington JP, Madej MJ, Dunican DS, Prokhortchouk E, Pennings S, Meehan RR

Development (Cambridge, England), 2009

doi:10.1242/dev.025577.

The non-methylated DNA-binding function of Kaiso is not required in early Xenopus laevis development.

Ruzov A, Savitskaya E, Hackett JA, Reddington JP, Prokhortchouk A, Madej MJ, Chekanov N, Li M, Dunican DS, Prokhortchouk E, Pennings S, Meehan RR

Development (Cambridge, England), 2009

doi:10.1242/dev.025569.

Identification of nuclear and cytoplasmic mRNA targets for the shuttling protein SF2/ASF.

Sanford JR, Coutinho P, Hackett JA, Wang X, Ranahan W, Caceres JF

PloS one, 2008

doi:10.1371/journal.pone.0003369.

xDnmt1 regulates transcriptional silencing in pre-MBT Xenopus embryos independently of its catalytic function.

Dunican DS, Ruzov A, Hackett JA, Meehan RR

Development (Cambridge, England), 2008

doi:10.1242/dev.016402.