Extracellular matrix chemistry tunes bacterial biofilm metabolism and optimizes fitness.

Li J, Squyres GR, Duong K, Reichhardt C, Parsek MR, Newman DK.

Proceedings of the National Academy of Sciences of the United States of America, 2026

doi:10.1073/pnas.2528666123.

Starvation enhances bacterial survival through drying and rewetting at the single cell level

Kwiecinski JV, Squyres GR, Or D, Newman DK.

2026

doi:10.64898/2026.01.12.697931.

Single-cell lysis patterns morphogenesis of eDNA in the matrix of <i>Pseudomonas aeruginosa</i> biofilms.

Squyres GR, Newman DK.

Proceedings of the National Academy of Sciences of the United States of America, 2025

doi:10.1073/pnas.2514210122.

Biofilms as more than the sum of their parts: lessons from developmental biology.

Squyres GR, Newman DK.

Current opinion in microbiology, 2024

doi:10.1016/j.mib.2024.102537.

Cell constriction requires processive septal peptidoglycan synthase movement independent of FtsZ treadmilling in Staphylococcus aureus.

Schäper S, Brito AD, Saraiva BM, Squyres GR, Holmes MJ, Garner EC, Hensel Z, Henriques R, Pinho MG.

Nature microbiology, 2024

doi:10.1038/s41564-024-01629-6.

Mycobacterial nucleoid-associated protein Lsr2 is required for productive mycobacteriophage infection.

Dulberger CL, Guerrero-Bustamante CA, Owen SV, Wilson S, Wuo MG, Garlena RA, Serpa LA, Russell DA, Zhu J, Braunecker BJ, Squyres GR, Baym M, Kiessling LL, Garner EC, Rubin EJ, Hatfull GF.

Nature microbiology, 2023

doi:10.1038/s41564-023-01333-x.

Designing efficient genetic code expansion in Bacillus subtilis to gain biological insights.

Stork DA, Squyres GR, Kuru E, Gromek KA, Rittichier J, Jog A, Burton BM, Church GM, Garner EC, Kunjapur AM.

Nature communications, 2021

doi:10.1038/s41467-021-25691-4.

Single-molecule imaging reveals that Z-ring condensation is essential for cell division in Bacillus subtilis.

Squyres GR, Holmes MJ, Barger SR, Pennycook BR, Ryan J, Yan VT, Garner EC.

Nature microbiology, 2021

doi:10.1038/s41564-021-00878-z.

Treadmilling FtsZ polymers drive the directional movement of sPG-synthesis enzymes via a Brownian ratchet mechanism.

McCausland JW, Yang X, Squyres GR, Lyu Z, Bruce KE, Lamanna MM, Söderström B, Garner EC, Winkler ME, Xiao J, Liu J.

Nature communications, 2021

doi:10.1038/s41467-020-20873-y.

A central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery.

Rohs PDA, Buss J, Sim SI, Squyres GR, Srisuknimit V, Smith M, Cho H, Sjodt M, Kruse AC, Garner EC, Walker S, Kahne DE, Bernhardt TG.

PLoS genetics, 2018

doi:10.1371/journal.pgen.1007726.

Treadmilling by FtsZ filaments drives peptidoglycan synthesis and bacterial cell division.

Bisson-Filho AW, Hsu YP, Squyres GR, Kuru E, Wu F, Jukes C, Sun Y, Dekker C, Holden S, VanNieuwenhze MS, Brun YV, Garner EC.

Science (New York, N.Y.), 2017

doi:10.1126/science.aak9973.

Facultative control of matrix production optimizes competitive fitness in Pseudomonas aeruginosa PA14 biofilm models.

Madsen JS, Lin YC, Squyres GR, Price-Whelan A, de Santiago Torio A, Song A, Cornell WC, Sørensen SJ, Xavier JB, Dietrich LE.

Applied and environmental microbiology, 2015

doi:10.1128/aem.02628-15.