The following equipment and microscope systems are available at the facility:
- Stereomicroscope Leica MZ12
- Motorised fluorescence stereomicroscope Nikon SMZ25
- Widefield Leica Thunder
- Laser scanning confocal microscope system Nikon AX/AR
- XLight V3 Crest Optics Spinning Disk Confocal
- Structure illumination module Crest Optics DeepSIM
- Automated slide scanner Olympus VS200
- Hybrid Open-top Light sheet system Alpenglow
- Robotic pippetting system Opentrons OT2
- Automated slide processing system BioGenex NanoVIP
- GPU-powered Workstation with AIVIA and Imaris for image analysis
- Cryostat Leica CM3050S
- Cryostat Thermo Scientific NX70
- Microtome Leica RM2135 (1 manual and 1 semi-automated)
- Vibratome Leica VT1000S (2 units)
The following services are available at the facility:
- Paraffin embedding and serial/step sectioning of tissue or whole embryo samples.
- Whole-mount in situ hybridisation/immunohistochemistry of early to mid-gestation mouse embryos.
- Section in situ hybridisation (mRNA, microRNA), immunohistochemistry, and immunofluorescence.
- Assisting and providing advice to users in the proper extraction of samples for histological analysis.
- Assisting in characterisation of Cre-lines.
- In situ sequencing for spatial transcriptomics
- Expansion microscopy