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Chemical Biology Core Facility

Small molecules play essential roles in many areas of basic research and are often used to address important biological questions.

Publications

Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer.

Dieter SM, Siegl C, Codó PL, Huerta M, Ostermann-Parucha AL, Schulz E, Zowada MK, Martin S, Laaber K, Nowrouzi A, Blatter M, Kreth S, Westermann F, Benner A, Uhrig U, Putzker K, Lewis J, Haegebarth A, Mumberg D, Holton SJ, Weiske J, Toepper LM, Scheib U, Siemeister G, Ball CR, Kuster B, Stoehr G, Hahne H, Johannes S, Lange M, Herbst F, Glimm H

Cell reports 2021

34289372. doi:10.1016/j.celrep.2021.109394.

Scaffold hopping computational approach for searching novel beta-Lactamase inhibitors.

Beshnova DA, Carolan C, Grigorenko VG, Rubtsova MY, Gbekor E, Lewis J, Lamzin VS, Egorov AM

BIOCHEMISTRY MOSCOW-SUPPLEMENT SERIES B-BIOMEDICAL CHEMISTRY 2020

doi:10.1134/S199075082002002X.

Two-dose recommendation for Human Papillomavirus vaccine can be extended up to 18 years - updated evidence from Indian follow up cohort study.

Basu P, Muwonge R, Bhatla N, Nene BM, Joshi S, Esmy PO, Poli URR, Joshi G, Verma Y, Zomawia E, Shastri SS, Pimple S, Anantharaman D, Prabhu PR, Hingmire S, Lucas E, Sauvaget C, Gheit T, Pawlita M, Malvi SG, Jayant K, Michel A, Siddiqi M, Sankaran S, Butt J, Varghese R, Rameshwari Ammal Kannan TP, Willhauck-Fleckenstein M, Divate U, Müller M, Waterboer T, Mishra G, Jadhav R, Sehr P, Vashist S, Thorat R, Tommasino M, Pillai MR, Sankaranarayanan R

Papillomavirus research (Amsterdam, Netherlands) 2019

30711698. doi:10.1016/j.pvr.2019.01.004.

Are two doses of human papillomavirus vaccine sufficient for girls aged 15-18 years? Results from a cohort study in India.

Bhatla N, Nene BM, Joshi S, Esmy PO, Poli URR, Joshi G, Verma Y, Zomawia E, Pimple S, Prabhu PR, Basu P, Muwonge R, Hingmire S, Sauvaget C, Lucas E, Pawlita M, Gheit T, Jayant K, Malvi SG, Siddiqi M, Michel A, Butt J, Subha Sankaran J, Kannan TPRA, Varghese R, Divate U, Willhauck-Fleckenstein M, Waterboer T, Müller M, Sehr P, Kriplani A, Mishra G, Jadhav R, Thorat R, Tommasino M, Radhakrishna Pillai M, Sankaranarayanan R

Papillomavirus research (Amsterdam, Netherlands) 2018

29578097. doi:10.1016/j.pvr.2018.03.008.

Drug-perturbation-based stratification of blood cancer.

Dietrich S, Oleś M, Lu J, Sellner L, Anders S, Velten B, Wu B, Hüllein J, da Silva Liberio M, Walther T, Wagner L, Rabe S, Ghidelli-Disse S, Bantscheff M, Oleś AK, Słabicki M, Mock A, Oakes CC, Wang S, Oppermann S, Lukas M, Kim V, Sill M, Benner A, Jauch A, Sutton LA, Young E, Rosenquist R, Liu X, Jethwa A, Lee KS, Lewis J, Putzker K, Lutz C, Rossi D, Mokhir A, Oellerich T, Zirlik K, Herling M, Nguyen-Khac F, Plass C, Andersson E, Mustjoki S, von Kalle C, Ho AD, Hensel M, Dürig J, Ringshausen I, Zapatka M, Huber W, Zenz T

The Journal of clinical investigation 2017

29227286. doi:10.1172/JCI93801.

Immunogenicity and HPV infection after one, two, and three doses of quadrivalent HPV vaccine in girls in India: a multicentre prospective cohort study

Sankaranarayanan R, Prabhu PR, Pawlita M, Gheit T, Bhatla N, Muwonge R, Nene BM, Esmy PO, Joshi S, Poli URR, Jivarajani P, Verma Y, Zomawia E, Siddiqi M, Shastri SS, Jayant K, Malvi SG, Lucas E, Michel A, Butt J, Vijayamma JMB, Sankaran S, Kannan TPRA, Varghese R, Divate U, Thomas S, Joshi G, Willhauck-Fleckenstein M, Waterboer T, Muller M, Sehr P, Hingmire S, Kriplani A, Mishra G, Pimple S, Jadhav R, Sauvaget C, Tommasino M, Pillai MR

LANCET ONCOLOGY 2016

26652797. doi:10.1016/S1470-2045(15)00414-3.


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