Studying how the environment impacts human health
Genome-wide association studies (GWAS) focusing on common single nucleotide polymorphism (SNPs) have advanced our understanding of the genetic causes of many traits and diseases. However, for some conditions, this method is reaching its limits. To better understand the genetic basis of diseases,…
EMBL researchers and collaborators have shown gut bacteria can alter how some carcinogens are metabolised and distributed elsewhere, that leads to bladder cancer. The study can help better understand how individuals' gut microbiota affects tumour growth.
This workshop aimed to identify quantitative molecular proxies of environmental exposures through bringing together experts from across epidemiology, toxicology, social science, and computational biology.
A study from the Hackett group at EMBL Rome shows that disrupting the gut microbiome of male mice increases the risk of disease in their future offspring.
This paper sets out a series of recommendations to adopt molecular biology approaches to understand the impact of environmental exposures on health.
This introductory course explored the complex interplay between genes and the environment in shaping human phenotypes.