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Recent Advances in Structural Biology of Membrane Proteins – Course and Conference Office

EMBO Workshop

Recent Advances in Structural Biology of Membrane Proteins

Overview

EMBL is committed to sharing research advances and sustaining scientific interaction throughout the coronavirus pandemic. We are delighted to announce that the conference is going virtual and invite you to join us online. The virtual conference includes live talks from invited speakers, short talk presenters, digital poster sessions and networking opportunities.

Conference Overview

Integral membrane proteins (IMPs) are encoded by 20-30 % of genes in a genome and provide key functions in the cell. Due to their hydrophobic nature, they are structurally and biochemically difficult to study. Traditionally, IMPs have been extracted using detergents which are a poor mimic of the lipid membrane and have been shown to denature membrane proteins. However, newly developed lipid-nanodisc approaches enable structural and functional studies of IMPs in a detergent-free, near-native membrane environment. Therefore, a central theme of this workshop is highlighting the importance of lipids in MP research and how they can be preserved.

Various experimental and computational tools, including novel expression and stabilisation strategies, have been developed to overcome the challenges posed by a variety of MPs. These technologies have delivered spectacular insights into membrane-protein structure, dynamics and function within the last few years. This conference will bring together researchers developing and applying these new methodologies. In addition to providing a forum to exchange the latest developments in the field, the conference provides excellent opportunities for early-career scientist in the field to learn all aspects of a variety of tools to study the structure and function of membrane proteins.

Session Topics

  • New mimetics for MP research
  • Expression and purification of MPs
  • Biophysics of lipid bilayers
  • X-ray methods for structural research of MPs
  • Binding proteins for structural and functional MP research
  • Advances in cryo-EM for small MPs
  • Cryo-EM and cryo-tomography on large MP complexes
  • Mass spectrometry and single-molecule FRET on MPs
  • Computational methods to probe structure and dynamics of MPs

Speakers

Keynote Speakers

Speakers

Tamir Gonen

Tamir Gonen

University of California, Los Angeles

USA

Scientific Organisers

Conference Officers

Maria Mercedes Bacadare Goitia

EMBL Heidelberg

Germany

Nathalie Sneider

EMBL Heidelberg

Germany

Programme

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  • The virtual conference includes live-streamed invited speakers and short talk presenters with Q&A sessions after each talk, as well as meet the speaker sessions. 
  • All digital poster presenters are encouraged to upload a recorded flash talk or narration with their digital poster and to schedule video calls during poster session times.
  • Information on the live stream and access to the discussion platform and digital posters will be provided shortly before the start of the event.
  • Access to the recorded talks will be available for 2 weeks after the start of the event.

All times in the programme below are shown as the time in Europe/Berlin.

To find out the equivalent time zone in your location, enter Berlin, the programme time and date along with your city into the Time Zone Converter.

Day 1 – Monday 29 November 2021
TimeSpeaker
Virtual Session 1:
New mimetics for MP research
11:15 – 11:45Talk title to be announced
Pil Seok Chae – Hanyang University, South Korea 
11:45 – 12:00Talk selected from abstracts
12:00 – 12:30Talk title to be announced
Manuela Zoonens – French National Centre
for Scientific Research, France
12:30 – 12:35Transition over to Meet the speakers from Virtual Session 1
12:35 – 12:55Meet the speakers in zoom rooms
12:55 – 13:35Lunch Break
13:35 – 14:45Virtual Poster Session 1
14:45 – 14:50Break
 Virtual Session 2:
Expression and purification of MPs
14:50 – 15:20Advanced methods for high-level (membrane)
protein production in mammalian cells
Jonathan Elegheert – French National Centre
for Scientific Research, France
15:20 – 15:35Talk selected from abstracts
15:35 – 16:05Talk title to be announced
Frank Bernhard – University of Frankfurt, Germany
16:05 – 16:50Keynote Speaker: Talk title to be announced
Stephen Sligar – University of Illinois at
Urbana-Champaign, USA
16:50 – 17:05Break
  Virtual Session 3:
Biophysics of lipid bilayers
17:05 – 17:35Talk title to be announced
Karen Edler – University of Bath, United Kingdom
17:35 – 17:50Talk selected from abstracts
17:50 – 18:20Membrane asymmetry: Why membrane proteins
might bother
Georg Pabst – University of Graz, Austria
18:20 – 18:25Transition over to Meet the speakers
from Virtual Session 2 and 3 
18:25 – 18:45Meet the speakers in zoom rooms
18:45 – 19:15Virtual Speed Networking
19:15 End Day 1 

Digital posters and pre-recorded talks as well as discussion channels will be available for registered participants throughout the whole virtual meeting.

Day 2 – Tuesday 30 November 2021
Time Speaker
 Virtual Session 4:
X-ray methods for structural research of MPs
14:00 – 14:30Talk title to be announced
Joerg Standfuss – Paul Scherrer Institute, Switzerland
14:30 – 14:45Talk selected from abstracts
14:45 – 15:00Talk selected from abstracts
15:00 – 15:15Break
 Virtual Session 5:
Binding proteins for structural and functional MP research
15:15 – 15:45Conformational trapping of membrane protein with sybodies
Markus Seeger – University of Zurich, Switzerland
15:45 – 16:00Talk selected from abstracts
16:00 – 16:30A helical epitope tag for structural analysis
of small membrane proteins
Randy Stockbridge – University of Michigan, USA
16:30 – 16:35Transition over to Meet the speakers from
Virtual Session 4 and 5 
16:35 – 16:55Meet the speakers in zoom rooms
16:55 – 18:05Virtual Poster Session 2
18:05 – 18:10Break
18:10 – 18:55Keynote Speaker: Talk title to be announced
Brian Kobilka – Stanford University, USA
 Virtual Session 6:
Advances in cryo-EM for small MPs I
18:55 – 19:25MicroED: conception, practice and future opportunities
Tamir Gonen –  UCLA, US
19:25 – 19:40Talk selected from abstracts
19:40 – 19:55Talk selected from abstracts
19:55 – 20:25Monitoring lipids in Cryo-EM structures
of membrane transporter and channels
Christine Ziegler – University of Regensburg, Germany 
20:25 – 20:35Break
 Virtual Session 7:
Advances in cryo-EM for small MPs II
20:35 – 21:05Talk title to be announced
Jiansen Jiang – National Heart Lung and Blood Institute, USA
21:05 – 21:20 Talk selected from abstracts
21:20 – 21:25Transition over to Meet the speakers from
Virtual Session 6 and 7 
21:25 – 21:45Meet the speakers in zoom rooms
21:45 – 22:15Virtual Bar Mixer
22:15End Day 2

Digital posters and pre-recorded talks as well as discussion channels will be available for registered participants throughout the whole virtual meeting.

Day 3 – Wednesday 1 December 2021
TimeSpeaker
 Virtual Session 8:
Cryo-EM and cryo-tomography on large MP complexes
14:00 – 14:30 cryo-CLEM of clathrin coated pits in intact cells
Ori Avinoam – Weizmann Institute of Science, Israel 
14:30 – 14:45Talk selected from abstracts
14:45 – 15:00Talk selected from abstracts
15:00 – 15:15Break
 Virtual Session 9:
Mass spectrometry and single-molecule FRET on MPs
15:15 – 15:45Talk title to be announced
Georg Krainer – University of Cambridge, UK
15:45 – 16:00Talk selected from abstracts
16:00 – 16:15Talk selected from abstracts
16:15 – 16:45Lipid metabolism: connecting the dots
Anne-Claude Gavin –  University of Geneva, Switzerland
16:45 – 16:50Transition over to Meet the speakers from
Virtual Session 8 and 9 
16:50 – 17:10Meet the speakers in zoom rooms
17:10 – 17:40Break
 Virtual Session 10:
Computational methods to probe structure and dynamics of MPs
17:40 – 18:10Multiscaling molecular dynamics simulation
of complex biomembranes
Kristyna Pluhackova – University of Stuttgart,  Germany 
18:10 – 18:25Talk selected from abstracts
18:25 – 18:55Atomistic structures and ensembles of MPs
in detergent micelles from SAXS-guided molecular dynamics simulations
Jochen Hub – Saarland University, Germany
18:55 – 19:00Transition over to Meet the speakers from Virtual Session 10
19:00 – 19:20Meet the speakers in zoom rooms
19:20 – 20:05Panel discussion
Chair: Sandro Keller – University of Graz, Austria
20:05 – 20:15 Closing remarks
20:15End Day 3

Digital posters and pre-recorded talks as well as discussion channels will be available for registered participants throughout the whole virtual meeting.

Practical information

Registration Fees and Abstract Submission

Registration Fees (include access to all of the talks, digital poster sessions and online group discussions, and help us cover our costs to run the event. For further information please refer to the FAQ page):

Academia190 Euro
PhD Student140 Euro
Industry240 Euro
EMBL StaffIntranet access

Accredited journalists may be eligible to register for a complimentary registration. Registrants may be required to provide accreditation or equivalent proof of press membership after registration. Please contact Nathalie Sneider for more information.

Confirmation and Payment

Registration will be on a first-come first-served basis. Your place can only be confirmed after payment of the registration fee.
Types of payments accepted are international bank transfers and credit card payments.

Abstract submission

Only registered participants are eligible to submit an abstract. We only accept online abstract submissions.

After you have logged in and successfully registered, you will receive an email asking you to submit your abstract.  Click on the link provided and enter your abstract in the text box provided. Alternatively you can submit your abstract by clicking on the link on the confirmation page directly after registering.

When submitting your abstract you can also apply for an oral or poster presentation. A selection process will take place with the results announced 2-3 weeks after the abstract submission deadline.

Financial Assistance

Financial Assistance

Registration Fee Waivers

All academic and student registrants are invited to apply for a registration fee waiver, provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO. The registration fee waiver covers the registration sum that you have paid to attend the meeting. Conference participants are not required to pre-pay the registration fee to be selected for a fee waiver for a virtual meeting. If you have already paid the registration fee and are awarded a fee waiver, it will be reimbursed after the meeting. Course participants are required to pay the course fee in advance, which will then be reimbursed after the recipient has attended the course.

Childcare Grants

For participants and speakers with childcare responsibilities there is the possibility to apply for a grant, provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO, to offset childcare costs incurred when participating at a virtual event. Eligible costs include fees for a babysitter or childcare facility or travel costs for a care giver. Please note that priority will be given to early stage researchers. Costs will be reimbursed after the meeting only once a reimbursement form and original receipts have been received. In order to apply for this grant, you must be registered by the abstract submission deadline.

Boehringer Ingelheim Fonds Travel Grant

Applies to selected courses only. Availability will be indicated during the abstract or motivation letter submission process.

This grant covers costs related to your attendance to the course (registration, travel and accommodation costs). The grant is restricted to PhD students and postdocs who conduct basic biomedical research.
Whether you are eligible to apply for a travel grant, depends on when you received your university entrance qualification (e.g. Abitur, A-Levels, High School Diploma, Final State Examination):

– for PhD and MD students, as well as graduates, the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course
– for postdocs, the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course

Application

Applications for financial assistance can be submitted via the submission portal* (for the submission of abstracts for conferences or the submission of motivation letters for courses) by completing the Financial Assistance Application Section (underneath the section for entering abstract/motivation letter information). The link to the portal can be found in the registration confirmation email that you will receive after registering for the conference or course.

For conferences, if you are not submitting an abstract, you can still apply for financial assistance in the submission portal. Read the instructions on how to apply for financial assistance.

Note that priority will be given to those submitting an abstract to present at the conference. In your application you will be asked to answer questions regarding your motivation for applying, and, for registration fee waivers, the reasons why your lab cannot fund your attendance and how your attendance will make a difference to your career. Application for financial support will not affect the outcome of your registration application.

*For some events, applications for Childcare Grants will still be done by email. Information about the grant will be sent out shortly after the abstract/motivation letter deadline. Please contact the event Conference Officer if you have any questions.

Selection

The scientific organisers will select the recipients of registration fee waivers during the abstract selection process for conferences and the participant selection process for courses. Results will be announced approximately 3 – 4 weeks before the event start date. Selection results do not impact your admission to the meeting. Registration fee waiver selection is based on your current work or study location, your motivation for applying, the reasons for needing financial support and the impact this event will have on your career. Childcare grants are allocated based on career stage, with priority given to early stage researchers.

Further details

Check out this list of external funding opportunities or get more information on attending the conference as an event reporter.

For further information about financial assistance please refer to the FAQ page.

Virtual Participation Guidelines

Guidelines

Please do:

  • Use the event-specific hashtag as communicated during the event for any related tweets
  • Tweet unless the speaker specifically says otherwise
  • Be mindful of unpublished data
  • Be respectful in tone and content

Please don’t:

  • Share your login details to the virtual conference platform with others
  • Broadcast the conference to unregistered participants
  • Capture, transmit or redistribute data presented at the meeting unless presenter gives explicit consent
  • Use offensive language in your posts
  • Engage in rudeness or personal attacks

Additional information can be found in our Code of Conduct.

Health and well-being

It is important to stay healthy and move around, especially when you are attending an event virtually. We have put together a few coffee break stretches and yoga videos in the events Slack workspace for you to enjoy during the event.

How to ask questions

Questions during and after the talks can be asked in live streaming platform. The chair moderates the questions and shares them with the speaker. If time runs out or you think of a question later, you can use Slack to ask your questions in the dedicated session channels or via direct message.

Time zone

The programme is planned based on Central European Summer Time (CEST), unless otherwise stated. As many virtual participants are attending from around the world, we do our best to accomodate as many timezones as possible when creating the programme. Please take your time zone into consideration when planning your attendance.

Virtual event platforms

We are using a virtual event platform for this conference. More information about the platform will be shared ahead of the conference.

Sponsors

Media Partners

EMBO reports, an EMBO Press journal

Open Biology, a Royal Society journal

Sponsorship Opportunities

We offer a variety of event sponsoring possibilities, with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget. Discounts are available for companies sponsoring multiple events at EMBL Heidelberg. View other conferences, or contact sponsoring@embl.de for further information.

If you are interested in becoming a media partner of this event, please visit our media partnerships webpage.

Warning

EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials. One current scam campaign of which we are aware is conducted using the name ‘Judy Eastman’ (judy@gopcontact.a2hosted.com) and entails approaches to sponsors offering sponsorship opportunities on EMBL’s behalf. Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences, symposia and courses is handled by EMBL directly and is sent from an official EMBL account. EMBL does not work with any external providers on sponsorship acquisition.

Please also note that:

  • EMBL never provides attendee lists for purchase. Any offers of such are fraudulent.
  • EMBL will never call or email you to ask for your credit card details or to request a payment.
  • All payments are on invoice.

Suspicious communications purportedly from, for or on behalf of EMBL should be reported to EMBL at the following email address sponsoring@embl.de.

EMBO Workshoo logo

Date: 29 Nov - 1 Dec 2021

Location: Virtual


Deadline(s):

Abstract submission: 4 Oct 2021

Registration: 1 Nov 2021


Organisers:

  • Panagiotis Kastritis
    Martin-Luther-Universität Halle-Wittenberg , Germany
    • Sandro Keller
      University of Graz, Austria

EMBL Courses and Conferences are kindly supported by our Corporate Partnership Programme

Founder partners

Corporate partners

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