Limb Development and Regeneration: New Tools for a Classic Model System

Overview

The programme, poster listing and onsite handout (with logistical information) are now available for download.

Symposium Overview

Recent years have seen a technological revolution in tools for studying dynamic gene regulation in cells and tissues – from chromatin and epigenomic analysis, through single-cell transcriptomics to the latest developments in 3D/4D imaging and sophisticated new computational modelling. Due to its extensive history, the developing vertebrate limb remains one of the ideal model systems to take advantage of this technological revolution. More is understood about the development of this organ than any other vertebrate organ, and yet a true integrated understanding still eludes us.

In the face of this technical revolution, the principle goal of this meeting is to bring together scientists representing the diversity of new technological approaches being used in this field. Key technological themes will be:

• Genome and epigenome regulation in limb development, regeneration and evolution
• The cellular basis of limb development (including single-cell molecular analyses)
• 3D/4D imaging, data integration and computer modelling of limb development

Session Topics

• Gene Regulation
• Patterning
• Patterning and Regeneration
• Morphogenesis and Modelling
• Growth
• Evolution

Speakers

Speakers and Trainers

Keynote Speakers

Len Pennacchio

Joint Genome Institute

USA

Elly Tanaka

Research Institute of Molecular Pathology

Austria

Deneen M. Wellik

University of Wisconsin-Madison

USA

Speakers

Kimberly Cooper

University of California, San Diego

USA

Joshua D. Currie

University of Toronto

Canada

Megan Davey

The University of Edinburgh

United Kingdom

Denis Duboule

University of Geneva, Ecole Polytechnique Fédérale de Lausanne

Switzerland

Renata Freitas

Institute for Molecular and Cell Biology

Portugal

Jérôme Gros

Institut Pasteur

France

Sevan Hopyan

University of Toronto

Canada

Marie Kmita

McGill University

Canada

Malcolm Logan

King’s College London

United Kingdom

Susan Mackem

National Cancer Institute

USA

Yoshihiro Morishita

RIKEN Center for Biosystems Dynamics Research

Japan

Ken Muneoka

Texas A&M University

USA

Paula Murphy

Trinity College Dublin

Ireland

Niamh Nowlan

Imperial College London

United Kingdom

Marian Ros

Institute of Biomedicine and Biotechnology of Cantabria, CSIC-SODERCAN-University of Cantabria

Spain

Alberto Roselló-Díez

Monash University

Australia

Karen E. Sears

University of California, Los Angeles

USA

James Sharpe

EMBL Barcelona

Spain

Koji Tamura

Tohoku University

Japan

Neil Vargesson

University of Aberdeen

United Kingdom

Jessica Whited

Harvard University

USA

Aimée Zuniga

University of Basel

Switzerland

Scientific Organisers

Marian Ros

Institute of Biomedicine and Biotechnology of Cantabria, CSIC-SODERCAN-University of Cantabria

Spain

James Sharpe

EMBL Barcelona

Spain

Miguel Torres

Spanish National Centre for Cardiovascular Research,

Spain

Conference Organisers

Christina Dollt

EMBL Heidelberg

Germany

Programme