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Chromatin and Epigenetics – Course and Conference Office

EMBL Conference

Chromatin and Epigenetics

Overview

EMBL is committed to sharing research advances and sustaining scientific interaction throughout the coronavirus pandemic. We are delighted to announce that the conference is going virtual and invite you to join us online. The virtual conference includes live talks from invited speakers, short talk presenters, digital poster sessions and networking opportunities.

Conference Overview

Epigenetics refers to heritable changes in gene expression that do not involve changes to the underlying DNA sequence. At least three systems including DNA methylation, histone modifications and non-coding RNAs (ncRNA) are considered to play fundamental roles in epigenetic regulation. Research over the last two decades has uncovered the role of epigenetics in a variety of human disorders and fatal diseases. Moreover influence of age, environment, lifestyle, and disease state on epigenetic states is being increasingly appreciated and actively studied. This conference provides an international forum for cutting edge research in chromatin and epigenetics. It provides the “focal hub” for people to present their research and exchange ideas in a virtual format. Renowned speakers will cover the latest advances in the field.

Session Topics

  • Heterochromatin and HP1
  • Developmental epigenetics
  • Chromatin regulation
  • Nucleosomes structure and function
  • Transcription and chromatin defects and diseases
  • Nuclear architecture
  • Chromatin and RNA modifications

Speakers

Keynote speaker

Speakers

Asifa Akhtar

Max Planck Institute of

Immunobiology and

Epigenetics

Germany

Nicola Iovino

Max Planck Institute of

Immunobiology and

Epigenetics

Germany

Cigall Kadoch

Dana-Farber Cancer

Institute and Harvard

Medical School

USA

Scientific Organisers

Asifa Akhtar

Max Planck Institute of

Immunobiology and

Epigenetics

Germany

Nicola Iovino

Max Planck Institute of

Immunobiology and

Epigenetics

Germany

Cigall Kadoch

Dana-Farber Cancer

Institute and Harvard

Medical School

USA

Conference Organiser

Maryann Heck

EMBL Heidelberg

Germany

Tim Nürnberger

EMBL Heidelberg

Germany

Programme

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  • The virtual conference includes live-streamed invited speaker talks and live-streamed selected short talks with live Q&A sessions after each talk
    as well as meet the speaker sessions.
  • All digital poster presenters are encouraged to upload a recorded flash talk or narration with their digital poster and to schedule video calls during poster session times.
  • Information on the live stream and access to the discussion platform and digital posters will be provided 1 week before the start of the event.

The following times are used in the programme below:

  • Central European Summer Time (CEST): eg. Berlin, Amsterdam, Paris
  • Eastern Daylight Time (EDT): eg. New York, Quebec

To find out the equivalent time zone in your location, enter Berlin, the CEST programme time and your city into the Time Zone Converter.

Day 1 – Monday 17 May 2021
TimeSpeaker
14:00 – 14:10 (CEST)
08:00 – 08:10 (EDT)
Opening remarks by scientific organisers
14:10 – 16:10 
(CEST)
08:10 – 10:10 (EDT)
Virtual Session 1: Developmental epigenetics
Chairs: Asifa Akhtar and Nicola Iovino
14:10 – 14:40 (CEST)
08:10 – 08:40 (EDT)
Amanda G. Fisher – MRC London Institute of Medical Sciences, UK
14:40 – 15:10 (CEST)
08:40 – 09:10 (EDT)
Cold-induced epigenetic switching
Caroline Dean – John Innes Centre, UK
15:10 – 15:40 (CEST)
09:10 – 09:40 (EDT)
Geneviève Almouzni – Institut Curie, France
15:40 – 15:55 (CEST)
09:40 – 09:55 (EDT)
The chromatin remodeler DDM1 prevents transposon
mobility through deposition of histone variant H2A.W

Frederic Berger – GMI, Austria
15:55 – 16:10 (CEST)
09:55 – 10:10 (EDT)
Distal and proximal cis-regulatory elements sense
X-chromosomal dosage and developmental state
at the Xist locus
Edda Schulz – Max Planck Institute for Molecular Genetics, Germany
16:10 – 16:20 
(CEST)
10:10 – 10:20 (EDT)
Break
16:20 – 16:50 
(CEST)
10:20 – 10:50 (EDT)
Meet all the speakers from Session 1
in individual Zoom rooms
16:50 – 17:50 
(CEST)
10:50 – 11:50 (EDT)
Virtual Poster Session 1
(live chats and video calls with poster presenters)
17:50 – 18:00 
(CEST)
11:50 – 12:00 (EDT)
Break
18:00 – 20:30
(CEST)
12:00 – 14:30 (EDT)
Virtual Session 2: Heterochromatin and HP1
Chairs: Cigall Kadoch and Giacomo Cavalli
18:00 – 18:30 (CEST)
12:00 – 12:30 (EDT)
Danesh Moazed – Harvard Medical School, USA
18:30 – 19:00 (CEST)
12:30 – 13:00 (EDT)
Nicola Iovino – Max Planck Institute of Immunobiology and Epigenetics, Germany
19:00 – 19:30 (CEST)
13:00 – 13:30 (EDT)
Can phase-separation explain heterochromatin properties?
Geeta J. Narlikar – University of California, San Francisco, USA
19:30 – 19:40 (CEST)
13:30 – 13:40 (EDT)
Break
19:40 – 19:55 (CEST)
13:40 – 13:55 (EDT)
Heterochromatin condensate formation and function
Gary Karpen – University of California, Berkeley, USA
19:55 – 20:10 (CEST)
13:55 – 14:10 (EDT)
Heterochromatin dynamics across scales
Serena Sanulli – Stanford University, USA
20:10 – 20:25 
(CEST)
14:10 – 14:25 (EDT)
Genome organization in and around the nucleolus
Raffaella Santoro – University of Zurich, Switzerland
20:25 – 20:30 
(CEST)
14:25 – 14:30 (EDT)
Transition (switch to individual Zoom rooms)
20:30 – 21:00 
(CEST)
14:30 – 15:00 (EDT)
Meet all the speakers from Session 2
in individual Zoom rooms
21:00 – 21:30 
(CEST)
15:00 – 15:30 (EDT)
Virtual speed networking
(Rotating through 5-min meet ups in groups of 2-3 people
in a breakout room)

Digital posters, recordings and discussion channels will be available for registered participants throughout the whole virtual conference (as well as 1 week before and 2 weeks after)

Day 2 – Tuesday 18 May 2021
TimeSpeaker
13:00 – 13:45 
(CEST)
07:00 – 07:45 (EDT)
Career fireside chat:
Panelists sharing career advice 
with PhD/postdoc participants
13:45 – 14:00 
(CEST)
07:45 – 08:00 (EDT)
Break
14:00 – 16:40 
(CEST)
08:00 – 10:40 (EDT)
Virtual Session 3: 
Transcription and chromatin defects and diseases
Chairs: Asifa Akhtar and Wolf Reik
14:00 – 14:30 (CEST)
08:00 – 08:30 (EDT)
Regulation of transcription elongation in development and disease
Karen Adelman – Harvard Medical School, USA
14:30 – 15:00 (CEST)
08:30 – 09:00 (EDT)
The distinct role of Polycomb and MLL proteins
in stem cell biology and cancer
Luciano Di Croce – Centre for Genomic Regulation, Spain
15:00 – 15:30 (CEST)
09:00 – 09:30 (EDT)
Shelley L. Berger – University of Pennsylvania
15:30 – 15:40 (CEST)
09:30 – 09:40 (EDT)
Break
15:40 – 16:10 (CEST)
09:40 – 10:10 (EDT)
Principles of epigenetics and chromatin in development
and human disease
Ali Shilatifard – Northwestern University, USA
16:10- 16:25 (CEST)
10:10- 10:25 (EDT)
The impact of cancer associated CTCF mutations
on chromatin structure and gene regulation
Jane Skok – NYU School of Medicine, USA
16:25 – 16:40 (CEST)
10:25 – 10:40 (EDT)
Chromatin regulation through intrinsic disorder:
What does it take to be a boundary/insulator?
Philipp Korber – Biomedical Center, LMU Munich, Germany
16:40 – 16:50 
(CEST)
10:40 – 10:50 (EDT)
Break
16:50 – 17:20 
(CEST)
10:40 – 11:20 (EDT)
Meet all the speakers from Session 3 
in individual Zoom rooms
17:20 – 18:20 
(CEST)
11:20 – 12:20 (EDT)
Virtual Poster Session 2
(live chats and video calls with poster presenters)
18:20-18:30 
(CEST)
12:20 – 12:30 (EDT)
Break
18:30 – 21:00 
(CEST)
12:15 – 14:05 (EDT)
Virtual Session 4: Chromatin regulation
Chairs: Anja Groth and Peter Becker
18:30 – 19:00 (CEST)
12:30 – 13:00 (EDT)
Asifa Akhtar – Max Planck Institute of Immunobiology
and Epigenetics, Germany
19:00 – 19:30 (CEST)
13:00 – 13:30 (EDT)
Nucleosome compaction, phase separation,
and Polycomb-Group maintenance of repression
Robert E. Kingston – Harvard Medical School, USA
19:30 – 20:00 (CEST)
13:30 – 14:00 (EDT)
Polycomb, inheritance and disease
Danny Reinberg – New York University School of Medicine, USA
20:00 – 20:10 (CEST)
14:00 – 14:10 (EDT)
Break
20:10 – 20:25 (CEST)
14:10 – 14:25 (EDT)
Role of chromatin condensates in establishing
nuclear architecture

Alessio Zippo – University of Trento, Italy
20:25 – 20:40 (CEST)
14:25 – 14:40 (EDT)
Structural basis of cGAS inhibition by the nucleosome
Robert McGinty – University of North Carolina at Chapel Hill, USA
20:40 – 20:55 (CEST)
14:40 – 14:55 (EDT)
Distinct PRC2 subunits regulate maintenance and
establishment of Polycomb repression during differentiation

Roberto Bonasio – University of Pennsylvania, USA
20:55 – 21:00 
(CEST)
14:55 – 15:00 (EDT)
Transition (switch to individual Zoom rooms)
21:00 – 21:30 
(CEST)
15:00 – 15:30 (EDT)
Meet all the speakers from Session 4 
in individual Zoom rooms
21:30 – 22:15 
(CEST)
15:30 – 16:15 (EDT)
Live Jazz and Virtual Bar Mixer

Digital posters, recordings and discussion channels will be available for registered participants throughout the whole virtual conference (as well as 1 week before and 2 weeks after)

Day 3 – Wednesday 19 May 2021
TimeSpeaker
13:15-13:45 
(CEST)
07:15-07:45 (EDT)
Meet the editors
in individual Zoom rooms
13:45-14:00 
(CEST)
07:45- 08:00 (EDT)
Break
14:00-16:40 
(CEST)
08:00-10:40 (EDT)
Virtual Session 5: Nucleosomes structure and function
Chairs: Geneviève Almouzni and Nicola Iovino
14:00- 14:30 (CEST)
08:00- 08:30 (EDT)
Chromatin replication and epigenome maintenance
Anja Groth – University of Copenhagen, Denmark
14:30- 15:00 (CEST)
08:30- 09:00 (EDT)
Cooperation, competition and combination: Principles of targeting the X for chromosome-wide regulation
Peter Becker – Ludwig-Maximilians-Universität München, Germany
15:00- 15:30 (CEST)
09:00- 09:30 (EDT)
Cigall Kadoch – Dana-Farber Cancer Institute and Harvard Medical School, USA
15:30- 15:40 (CEST)
09:30- 09:40 (EDT)
Break
15:40- 16:10 (CEST)
09:40- 10:10 (EDT)
Some assembly required: Structure and function of chromatin assembly factors and remodelers
Karolin Luger – University of Colorado Boulder, USA
16:10- 16:25 (CEST)
10:10- 10:25 (EDT)
The non-canonical SMC protein SMCHD1 has separable roles in long range chromatin interactions
and gene silencing
Marnie Blewitt – Walter and Eliza Hall Institute of Medical Research, Australia
16:25-16:40 (CEST)
10:25- 10:40 (EDT)
Genetic and epigenetic regulation
of imprinting control regions
Tuncay Baubec – University of Zurich, Switzerland
16:40-16:50 
(CEST)
10:40- 10:50 (EDT)
Break
16:50-17:20 
(CEST)
10:40- 11:20 (EDT)
Meet all the speakers from Session 5 
in individual Zoom rooms
17:20-18:20 
(CEST)
11:20- 12:20 (EDT)
Virtual Poster Session 3
(live chats and video calls with poster presenters)
18:20-18:30 
(CEST)
12:20- 12:30 (EDT)
Break
18:30-21:00 
(CEST)
12:30- 15:00 (EDT)
Virtual Session 6: Nuclear architecture
Chairs: Karolin Luger and Luciano Di Croce
18:30- 19:00 (CEST)
12:30- 13:00 (EDT)
Enhancer promoter communication during embryonic development
Eileen Furlong – EMBL Heidelberg, Germany
19:00-19:30 (CEST)
13:00-13:30 (EDT)
Principles and functional role of 3D genome folding
Giacomo Cavalli – Institute of Human Genetics – CNRS, France
19:30-20:00 (CEST)
13:30-14:00 (EDT)
Visualizing variable chromatin structures and robust transcriptional control
Alistair Boettiger – Stanford University, USA
20:00-20:10 (CEST)
14:00-14:10 (EDT)
Break
20:10-20:25 (CEST)
14:10-14:25 (EDT)
Nonlinear control of transcription levels through
enhancer-promoter interactions

Luca Giorgetti – Friedrich Miescher Institute for Biomedical Research, Switzerland
20:25-20:40 (CEST)
14:25-14:40 (EDT)
Rapid reorganization of the 3D genome reveals principal features of chromosome architecture
Elzo de Wit – Oncode Institute & Netherlands Cancer Institute, The Netherlands
20:40- 20:55 (CEST)
14:40- 14:55 (EDT)
Chromosomal coordination and differential structure
of asynchronous replicating regions

Yehudit Bergman – The Hebrew University Medical School, Israel
20:55-21:00 
(CEST)
14:55- 15:00 (EDT)
Transition (switch to individual Zoom rooms)
21:00-21:30 (CEST)
15:00- 15:30 (EDT)
Meet all the speakers from Session 6 
in individual Zoom rooms

Digital posters, recordings and discussion channels will be available for registered participants throughout the whole virtual conference (as well as 1 week before and 2 weeks after)

Day 4 – Thursday 20 May 2021
TimeSpeaker
14:00- 15:45 
(CEST)
08:00 – 09:45 (EDT)
Virtual Session 7: Chromatin and RNA modifications
Chairs: Caroline Dean and Cigall Kadoch
14:00 – 14:30 (CEST)
08:00 – 08:30 (EDT)
Nuclear condensates in gene regulation and disease
Richard A. Young – Whitehead Institute for Biomedical Research, USA
14:30 – 15:00 (CEST)
08:30 – 09:00 (EDT)
Chemical approaches to studying chromatin
Tom Muir – Princeton University, USA
15:00 – 15:15 (CEST)
09:00 – 09:15 (EDT)
Inducible condensation of chromatin regulators drives
rapid transcriptional changes

Ritwick Sawarkar – University of Cambridge, UK
15:15 – 15:30 (CEST)
09:15 – 09:30 (EDT)
Single-molecule systems for cancer research
and diagnostics: Decoding the epigenome
of pediatric gliomas
Efrat Shema – Weizmann Institute of Science, Israel
15:30 – 15:45 (CEST)
09:30 – 09:45 (EDT)
Control of enhancer activity by DNA methylation
Arnaud Krebs – EMBL Heidelberg, Germany
15:45 – 16:00 (CEST)
09:45 – 10:00 (EDT)
Break
16:00- 16:45 
(CEST)
10:00 – 10:45 (EDT)
Keynote: Single cell multi-omics landscape of development and ageing 
Wolf Reik – Babraham Institute, UK
16:45- 16:55 
(CEST)
10:45 – 10:55 (EDT)
Poster prize talk 1
16:55- 17:05 
(CEST)
10:55 – 11:05 (EDT)
Poster prize talk 2
17:05- 17:15 
(CEST)
11:05 – 11:15 (EDT)
Poster prize talk 3
17:15- 17:25 
(CEST)
11:15 – 11:25 (EDT)
Closing remarks
17:25- 17:55 
(CEST)
11:25 – 11:55 (EDT)
Meet all the speakers from Session 7 
in individual Zoom rooms

Digital posters, recordings and discussion channels will be available for registered participants throughout the whole virtual conference (as well as 1 week before and 2 weeks after)

Practical information

Registration Fees and Abstract Submission

Registration Fees (include access to all of the talks, digital poster sessions and online group discussions, and help us cover our costs to run the event.) 
For further information please refer to the FAQ page):

Academia190 Euro
PhD Student140 Euro
Industry240 Euro
EMBL StaffIntranet access

NO visa support letters will be issued until payment of the registration fee is confirmed.

Accredited journalists may be eligible to register for a reduced press rate or in some cases for complimentary registration. Registrants may be required to provide accreditation or equivalent proof of press membership after registration. Please contact Tim Nürnberger for more information.

Confirmation and Payment

Registration will be on a first-come first-served basis. Your place can only be confirmed after payment of the registration fee.
Types of payments accepted are international bank transfers (only up to 8 weeks before event) and credit card payments.

Abstract submission

Only registered participants are eligible to submit an abstract. We only accept online abstract submissions. 

After registration you can submit your abstract via a separate link that will be provided in the email confirmation. Alternatively, you can access the link on the confirmation page directly after registering. The same login credentials are used for both processes.

Please note:

Title: The title should not exceed 20 words. Only the first word of the title should start with a capital letter and the rest of the title should be in lowercase.

Authors and Affiliations: Please fill in the author’s details as requested in the online form. The compulsory details are: First Name, Last Name, Organisation Name (Affiliation or Company), Country and Email. Mark only one author as the role of First author and please don’t forget to indicate who will be presenting. The order of the authors will be listed as follows: First Author, Co-First Author (alphabetically if multiple), co-author(s) (in the order added by the submitter).

Presentation Types: When submitting your abstract, you can apply for an oral or digital poster presentation. A selection process will take place with the results announced 2-3 weeks after the abstract submission deadline.

Please check our FAQs pages for further information on how to submit an abstract.

Financial Assistance

Financial Assistance

Registration Fee Waivers

All academic and student registrants are invited to apply for a registration fee waiver, provided by the EMBL Advanced Training Centre Corporate Partnership Programme. The registration fee waiver covers the registration sum that you have paid to attend the meeting. Conference participants are not required to pre-pay the registration fee to be selected for a fee waiver for a virtual meeting. If you have already paid the registration fee and are awarded a fee waiver, it will be reimbursed after the meeting. Course participants are required to pay the course fee in advance, which will then be reimbursed after the course to the fee waiver recipients.

Childcare Grants

For participants with children, there is the possibility to apply for a childcare grant provided by the EMBL Advanced Training Centre Corporate Partnership Programme, to offset childcare costs incurred by participants or speakers when participating at a virtual event. Eligible costs include fees for a babysitter or childcare facility or travel costs for a care giver. Please note that priority will be given to early stage researchers. A maximum amount of 500 EUR can be awarded per participant selected for the virtual childcare grant. Costs will be reimbursed after the meeting only once a reimbursement form and original receipts have been received. In order to apply for this grant, you must be registered by the abstract submission deadline.

Application

Applications for financial assistance can be submitted via the submission portal* (for the submission of abstracts for conferences or the submission of motivation letters for courses) by completing the Financial Assistance Application Section (underneath the section for entering abstract/motivation letter information). The link to the portal can be found in the registration confirmation email that you will receive after registering for the conference or course.

For conferences, if you are not submitting an abstract, you can still apply for financial assistance in the submission portal by following the instructions here. Note that priority will be given to those submitting an abstract to present at the conference. In your application you will be asked to answer questions regarding your motivation for applying, and, for registration fee waivers, the reasons why your lab cannot fund your attendance and how your attendance will make a difference to your career. Application for financial support will not affect the outcome of your registration application.

*For some events, applications for Childcare Grants will still be done by email. Information about the grant will be sent out shortly after the abstract/motivation letter deadline. Please contact the event Conference Officer if you have any questions.

Selection

The scientific organisers will select the recipients of registration fee waivers during the abstract selection process for conferences and the participant selection process for courses. Results will be announced approximately 3 – 4 weeks before the event start date. Selection results do not impact your admission to the meeting. Registration fee waiver selection is based on your current work or study location, your motivation for applying, the reasons for needing financial support and the impact this event will have on your career. Childcare grants are allocated based on career stage, with priority given to early stage researchers.

Further details

A list of external funding opportunities can be found here, and information on attending a conference as an event reporter here.

For further information about financial assistance please refer to the FAQ page.

Virtual Participation Guidelines

Guidelines

Please do:

  • Use the event-specific hashtag as communicated during the event for any related tweets
  • Tweet unless the speaker specifically says otherwise
  • Be mindful of unpublished data
  • Be respectful in tone and content

Please don’t:

  • Share Slack, live stream or poster session links with others
  • Broadcast the conference to unregistered participants
  • Capture, transmit or redistribute data presented at the meeting unless presenter gives explicit consent
  • Use offensive language in your posts
  • Engage in rudeness or personal attacks

Additional information can be found in our Code of Conduct.

Health and well-being

It is important to stay healthy and move around, especially when you are attending an event virtually. We have put together a few coffee break stretches and yoga videos. You can find these under ‘resources’ on the conference platform.

How to ask questions

Please use the Q&A function. It is possible to send a direct message to participants, poster presenters, and speakers within the conference platform.

If you have any other questions, you can go to the Help Desk on the conference platform. Click on ‘more’ on the top menu and click Help Desk. 

Time zone

The programme is planned based on Central European Time (CET) or Central European Summer Time (CEST) unless otherwise stated. As many virtual participants are attending from around the world, we do our best to accommodate as many timezones as possible when creating the programme. Please take your time zone into consideration when planning your attendance. Remember to set your time zone in your account. 

Virtual event platforms

We are using a virtual event platform for this conference. More information about the platform will be shared ahead of the conference.

Zoom: The virtual event platform will use Zoom for live sessions and we recommend you download the Zoom app in advance of the conference to ensure you get full interactivity.

Sponsors

Gold Sponsors

10x Genomics Logo

Silver Sponsor

Dovetail Genomics Logo

Media Partners

EMBO Journal, an EMBO Press journal

Journal of Cell Science, a The Company of Biologists journal

Open Biology, a Royal Society journal

Wiley

Sponsorship Opportunities

We offer a variety of event sponsoring possibilities, with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget. Discounts are available for companies sponsoring multiple events at EMBL Heidelberg. View other conferences, or contact sponsorship@embl.de for further information.

If you are interested in becoming a media partner of this event, please visit our media partnerships webpage.

Date: 17 - 20 May 2021

Location: Virtual


Deadline(s):

Abstract submission: Closed

Registration: 19 Apr 2021


Contact: Tim Nürnberger

Download event poster

Chromatin and Epigenetics poster

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