In situ Structural Biology: From Cryo-EM to Integrative Modelling – Virtual

Overview

Conference Overview

There is an increasing awareness that mechanistic structural information on molecular machines is ideally generated within the context of intact cells in order to fully grasp how they function in a complex native environment. Recent technological advances have nurtured the development of such in situ structural biology approaches in several disciplines, including cryo-EM, mass spectrometry, super-resolution microscopy, NMR, computational modelling and others.

This conference will bring together experts and early stage researchers from the separate fields

• to provide a platform for structural biology within the cellular context
• to stimulate discussions about how to meaningfully integrate data from different methods
• to define what types of biological questions can already be addressed using in situ structural biology and which might be approached in the future

Session Topics

• Imaging across scales
• Structural analysis in situ
• Molecular sociology
• Biophysical analysis in cells
• Integrative modelling

Speakers and Organisers

Keynote Speakers

Wolfgang Baumeister

Max Planck Institute of Biochemistry,

Germany

Zaida (Zan) Ann Luthey-Schulten

University of Illinois at Urbana-Champaign,

USA

Speakers

Lia Addadi

Weizmann Institute of Science,

Israel

Tanmay Bharat

University of Oxford

UK

David S. Goodsell

Scripps Research,

USA

Gerhard Hummer

Max Planck Institute of Biophysics,

Germany

Wanda Kukulski

MRC Laboratory of Molecular Biology,

UK

Edward A. Lemke

IMB, JGU and EMBL Heidelberg,earch,

Germany

Paola Picotti

ETH Zürich,

Switzerland

Gaia Pigino

Max Planck Institute of Molecular Cell Biology and Genetics,

Germany

Martin Pilhofer

ETH Zürich,

Switzerland

Juri Rappsilber

TU Berlin,

Germany

Jonas Ries

EMBL Heidelberg,

Germany

Andrej Sali

University of California, San Francisco,

USA

Mikhail Savitski

EMBL Heidelberg,

Germany

Beata Turonova

EMBL Heidelberg,

Germany

Elizabeth Villa

University of California, San Diego,

USA

Giulia Zanetti

Birkbeck, University of London,

UK

Scientific Organisers

Martin Beck

Max Planck Institute of Biophysics,

Germany

Jan Kosinski

EMBL Hamburg,

Germany

Julia Mahamid

EMBL Heidelberg,

Germany

Course Organisers

Tim Nürnberger

EMBL Heidelberg

Germany

Diah Yulianti

EMBL Heidelberg,

Germany

Programme