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tumour

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21 July 2020 Top row: The evolution of tumour cells (green) within a normal organoid (grey) shown in three panels. Lower row: Surface rendition of tumour cells and labels new cells that arise from a single cell in the same colour.

A tool to improve cancer research

Science EMBL scientists have created a new, realistic 3D testbed that could help achieve the goal of stopping cancers before they start by studying cancer cells as they first form.

2020

science

5 February 2020

Cancer mutations occur decades before diagnosis

Science Researchers at EMBL’s European Bioinformatics Institute (EMBL-EBI) and the Francis Crick Institute have analysed the whole genomes of over 2600 tumours from 38 different cancer types to determine the chronology of genomic changes during cancer development.

2020

science

5 February 2020

Chromothripsis in human cancer

Science Researchers at Harvard Medical School and EMBL-EBI have carried out the largest analysis across cancer types of the newly discovered mutational phenomenon chromothripsis.

2020

science

5 February 2020

Finding genetic cancer risks

Science Using the data from the Pan-Cancer project EMBL scientists describe how our genetic background influences cancer development.

2020

science

11 August 2013

From fireman to arsonist

Science Like a fireman who becomes an arsonist, a protein that prevents cells becoming cancerous can also cause tumours, scientists at the European Molecular Biology Laboratory (EMBL) in Grenoble, France, have discovered. The finding, published today in Nature Structural and Molecular Biology, stems…

2013

science

11 February 2013

One disease, two mechanisms

Science While prostate cancer is the most common cancer in elderly Western men it also, but more rarely, strikes patients aged between 35 and 50. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, in collaboration with several other research teams in Germany*, have…

2013

science

22 April 2012 Abstract image showing DNA code

A matter of priorities

Science Just as banks store away only the most valuable possessions in the most secure safes, cells prioritise which genes they guard most closely, researchers at the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) have found. The study, published online today…

2012

science

12 February 2007

A signal that protects the liver from hepatitis and cancer

Science Liver cancer is one of the deadliest cancers worldwide; every year sees more than 400,000 new cases, and most of the victims die in less than one year. Despite extensive research, the underlying molecular mechanisms of the disease are poorly understood. A new study by researchers from the Mouse…

2007

science

4 September 2005

A new link between stem cells and tumors

Science Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg and the Institute of Biomedical Research of the Parc Científic de Barcelona (IRB-PCB) have now added key evidence to claims that some types of cancer originate with defects in stem cells. The study, reported this week in…

2005

science

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