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The Pan-Cancer project

EMBL co-leads most comprehensive study of genetic causes of cancer…

By Mathias Jäger

Science

Characterising RNA alterations in cancer

The largest and most comprehensive catalogue of cancer-specific RNA alterations reveals new insights into the cancer genome.…

By Vicky Hatch

Science

Cancer mutations occur decades before diagnosis

Researchers at EMBL’s European Bioinformatics Institute (EMBL-EBI) and the Francis Crick Institute have analysed the whole genomes of over 2600 tumours from 38 different cancer types to determine the chronology of genomic changes during cancer development.…

By Vicky Hatch

Science

Studying DNA rearrangement to understand cancer

Using the dataset from the Pan-Cancer project, scientists has developed methods to group, classify, and describe large rearrangements of the genome that are a key driver of cancer.…

By Fabian Oswald

Science

Scientists identify new genetic drivers of cancer

Analysis of whole cancer genomes gives key insights into the role of the non-coding genome in cancer…

By Cella Carr

Science

Chromothripsis in human cancer

Researchers at Harvard Medical School and EMBL-EBI have carried out the largest analysis across cancer types of the newly discovered mutational phenomenon chromothripsis.…

By Vicky Hatch

Science

Finding genetic cancer risks

Using the data from the Pan-Cancer project EMBL scientists describe how our genetic background influences cancer development.…

By Fabian Oswald

Science

Miniature testing of drug pairs on tumour biopsies

Combinations of cancer drugs can be quickly and cheaply tested using a novel microfluidic device…

By Emma Steer

Science

From fireman to arsonist

Like a fireman who becomes an arsonist, a protein that prevents cells becoming cancerous can also cause tumours, scientists at the European Molecular Biology Laboratory (EMBL) in Grenoble, France, have discovered. The finding, published today in Nature Structural and Molecular Biology, stems…

By Guest author(s)

Science

One disease, two mechanisms

While prostate cancer is the most common cancer in elderly Western men it also, but more rarely, strikes patients aged between 35 and 50. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, in collaboration with several other research teams in Germany*, have…

By Guest author(s)

Science

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