Combi-seq: a leap forward for personalised cancer therapy
Science Researchers have come up with a way to test the efficacy of hundreds of anticancer drug combinations – simultaneously, rapidly, and accurately.
2022
science
A tool to improve cancer research
Science EMBL scientists have created a new, realistic 3D testbed that could help achieve the goal of stopping cancers before they start by studying cancer cells as they first form.
2020
science
The Pan-Cancer project
Science EMBL co-leads most comprehensive study of genetic causes of cancer
2020
science
Characterising RNA alterations in cancer
Science The largest and most comprehensive catalogue of cancer-specific RNA alterations reveals new insights into the cancer genome.
2020
science
Cancer mutations occur decades before diagnosis
Science Researchers at EMBL’s European Bioinformatics Institute (EMBL-EBI) and the Francis Crick Institute have analysed the whole genomes of over 2600 tumours from 38 different cancer types to determine the chronology of genomic changes during cancer development.
2020
science
Studying DNA rearrangement to understand cancer
Science Using the dataset from the Pan-Cancer project, scientists has developed methods to group, classify, and describe large rearrangements of the genome that are a key driver of cancer.
2020
science
Scientists identify new genetic drivers of cancer
Science Analysis of whole cancer genomes gives key insights into the role of the non-coding genome in cancer
2020
science
Chromothripsis in human cancer
Science Researchers at Harvard Medical School and EMBL-EBI have carried out the largest analysis across cancer types of the newly discovered mutational phenomenon chromothripsis.
2020
science
Finding genetic cancer risks
Science Using the data from the Pan-Cancer project EMBL scientists describe how our genetic background influences cancer development.
2020
science
Miniature testing of drug pairs on tumour biopsies
Science Combinations of cancer drugs can be quickly and cheaply tested using a novel microfluidic device
2018
science
From fireman to arsonist
Science Like a fireman who becomes an arsonist, a protein that prevents cells becoming cancerous can also cause tumours, scientists at the European Molecular Biology Laboratory (EMBL) in Grenoble, France, have discovered. The finding, published today in Nature Structural and Molecular Biology, stems…
2013
science
One disease, two mechanisms
Science While prostate cancer is the most common cancer in elderly Western men it also, but more rarely, strikes patients aged between 35 and 50. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, in collaboration with several other research teams in Germany*, have…
2013
science
A matter of priorities
Science Just as banks store away only the most valuable possessions in the most secure safes, cells prioritise which genes they guard most closely, researchers at the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) have found. The study, published online today…
2012
science
A signal that protects the liver from hepatitis and cancer
Science Liver cancer is one of the deadliest cancers worldwide; every year sees more than 400,000 new cases, and most of the victims die in less than one year. Despite extensive research, the underlying molecular mechanisms of the disease are poorly understood. A new study by researchers from the Mouse…
2007
science
A new link between stem cells and tumors
Science Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg and the Institute of Biomedical Research of the Parc Científic de Barcelona (IRB-PCB) have now added key evidence to claims that some types of cancer originate with defects in stem cells. The study, reported this week in…
2005
science
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