mutation
Fighting cardiovascular disease with acne drug
Researchers have found the cause of dilated cardiomyopathy – a leading cause of heart failure – and identified a potential treatment for it: a…
Unpicking the complexity of DNA mutations
DNA damage caused by chemical mutagens is not repaired immediately and can create more genetic diversity in…
DNA damage and faulty repair jointly cause mutations
DNA mutations are caused by a combination of DNA damage and repair, shows study by EMBL-EBI and…
The Pan-Cancer project
EMBL co-leads most comprehensive study of genetic causes of…
Potential new drug target for cystic fibrosis
Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg and Regensburg University, both in Germany, and the University of…
The mutation police
Scientists at the EMBL-European Bioinformatics Institute (EMBL-EBI) and the MRC Laboratory of Molecular Biology in the UK have discovered how our…
A matter of priorities
Just as banks store away only the most valuable possessions in the most secure safes, cells prioritise which genes they guard most closely,…
Rigged to explode?
An inherited mutation in a gene known as the guardian of the genome is likely the link between exploding chromosomes and some particularly aggressive…
An unexpected way to cause leukaemia
Leukaemia – cancer of blood or bone marrow – is caused by mutations that allow defective blood cells to accumulate and displace healthy blood. To…
A gene that protects from kidney disease
Researchers from the European Molecular Biology Laboratory (EMBL) and the University of Michigan have discovered a gene that protects us against a…
A first glimpse of the influenza replication machine
In 1918, 50 million people died during a worldwide influenza pandemic caused by mutation of a bird-specific strain of the influenza virus. Recently…
Defusing dangerous mutations
Mutations in genes are the basis of evolution, so we owe our existence to them. Most mutations are harmful, however, because they cause cells to…
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