3 June 2012

Shape-shifting shell

Science, Science & Technology As a retrovirus matures, the two parts of its shell protein (red and blue or yellow and blue) dramatically rearrange themselves, twisting and moving away from each other. (Credit: EMBL/T.Bharat) Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have for the…



12 January 2012

Evolution by ‘copy-paste’

Science, Science & Technology A team of geneticists and computational biologists at the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI), the Wellcome Trust Sanger Institute and Cancer Research UK reveal how an ancient mechanism is involved in gene control and continues to drive genome…



23 June 2009 Lattice maps for immature HIV particles. The 3D computer reconstruction shows the immature Gag lattice of HIV that matures to form the protein shell of the infecious virus. Maps are shown in perspective such that hexamers on the rear surface of the particle appear smaller. The side of the particle toward the viewer lacks ordered Gag. IMAGE: John Briggs/EMBL

New electron microscopy images reveal the assembly of HIV

Science Scientists at the European Molecular Biology Laboratory (EMBL) and the University Clinic Heidelberg, Germany, have produced a three-dimensional reconstruction of HIV (Human Immunodeficiency Virus), which shows the structure of the immature form of the virus at unprecedented detail. Immature HIV is…



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